LETTERS TO THE EDITOR

Ultrasound measurement of the corpus callosum and neural development

Sir, the recent report on “ultrasound measurement of the corpus callosum and neural development” is very interesting[1]. Liu et al. reported that “corpus callosum growth in premature infants is associated with neurobehavioral development during the early extrauterine stage[1].” In fact, the use of 3D ultrasound seems to be useful to determine corpus callosum abnormality[2]. However, the genetic counseling based on its result remains controversial[2]. Santo et al. found that normal outcome could be observed in about 65–75% of cases with detected abnormalities of corpus callosum[3]. The diagnostic sensitivity of the ultrasound is also the topic to be considered[4]. Inaccuracy of ultrasound can be commonly seen and this leads to the requirement of additional MRI investigation[5].

[1] Liu F, Cao S, Liu J, Du Z, Guo Z, Ren C. Ultrasound measurement of the corpus callosum and neural development of premature infants. Neural Regen Res 2013;8:2432-2440.

[2] De Catte L, De Keersmaeker B, Claus F. Prenatal neurologic anomalies: sonographic diagnosis and treatment. Paediatr Drugs. 2012;14:143-155.

[3] Santo S, D’Antonio F, Homfray T, Rich P, Pilu G, Bhide A, Thilaganathan B, Papageorghiou AT. Counseling in fetal medicine: agenesis of the corpus callosum. Ultrasound Obstet Gynecol. 2012;40:513-521.

[4] Karl K, Kainer F, Heling KS, Chaoui R. Fetal neurosonography: extended examination of the CNS in the fetus. Ultraschall Med. 2011;32:342-361.

[5] Wald M, Lawrenz K, Deutinger J, Weninger M. Veri fi cation of anomalies of the central nervous system detected by prenatal ultrasound. Ultraschall Med. 2004;25:214-217.

Professor Viroj Wiwanitkit, M.D., Hainan Medical University, China.

Accepted: 2014-01-04

Wiwanitkit V. Ultrasound measurement of the corpus callosum and neural developmeng. Neural Regen Res. 2014;9(3):336.

Viroj Wiwanitkit, M.D., Hainan Medical University, China, wviroj@yahoo.com.

10.4103/1673-5374.128233 http://www.nrronline.org/