miRNA-124 in immune system and immune disorders
2017-01-16 03:42ZhenQINPengyuanWANGDingfengSUXiaLIU
中國藥理學(xué)與毒理學(xué)雜志 2017年10期
Zhen QIN,Peng-yuan WANG,Ding-feng SU,Xia LIU
(Department of Pharmacology,Second Military Medical University,Shanghai 200433,China）
T2-19
miRNA-124 in immune system and immune disorders
Zhen QIN,Peng-yuan WANG,Ding-feng SU,Xia LIU
(Department of Pharmacology,Second Military Medical University,Shanghai 200433,China）
In recent years,miR-124 has emerged as a critical modulator of immunity and inflammation.Here,we summarize studies on the function and mechanism of miR-124 in the immune system and immunity-related diseases.They indicated that miR-124 exerts a crucial role in the development of immune system,regulation of immune responses,and inflammatory disorders.It is evident that miR-124 may serve as an informative diagnostic biomarker and therapeutic target in the future.
miRNA-124;biomarker;target;immunity;immune disorders
The project supported by National Natural Science Foundation of China(grant number 81273606,81473259 to XL,81603116 to YS);and National Science and Technology Major Project(grant number 2014ZX09J14103-08C to XL)
Xia LIU,Tel:13764083416,E-mail:lxflying@aliyun.com;Ding-Feng SU,E-mail:dfsu@smmu.edu.cn
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