李金星,郭慶環(huán),張林昌
(天津市第五中心醫(yī)院 放射科,天津300451)
CT、MRI在眼眶海綿狀血管瘤與眼眶神經(jīng)鞘瘤影像學(xué)鑒別診斷中的研究
李金星,郭慶環(huán),張林昌*
(天津市第五中心醫(yī)院 放射科,天津300451)
目的對(duì)CT、MRI在眼眶海綿狀血管瘤與眼眶神經(jīng)鞘瘤的影像學(xué)鑒別診斷中的應(yīng)用價(jià)值進(jìn)行研究。方法選取我院2015年3月至2016年3月收治的經(jīng)CT診斷為眼眶海綿狀血管瘤患者38例和眼眶神經(jīng)鞘瘤患者45例,經(jīng)MRI診斷為眼眶海綿狀血管瘤患者41例和眼眶神經(jīng)鞘瘤患者39例。對(duì)所有患者進(jìn)行腫瘤鑒別診斷,主要分為定性診斷符合和定位診斷符合,定性診斷符合是影像學(xué)診斷與病理診斷結(jié)果一致;定位診斷符合是影像學(xué)診斷與手術(shù)定位結(jié)果一致。分別計(jì)算CT、MRI的定性、定位診斷符合率。結(jié)果CT診斷的38例眼眶海綿狀血管瘤患者定性診斷正確的31例,定性診斷符合率為81.58%;定位診斷正確33例,定位診斷符合率為86.84%。CT診斷的45例眼眶神經(jīng)鞘瘤患者定性診斷正確的39例,定性診斷符合率為86.67%;定位診斷正確37例,定位診斷符合率82.22%。MRI診斷的41例眼眶海綿狀血管瘤患者定性診斷正確的38例,定性診斷符合率為92.68%;定位診斷正確39例,定位診斷符合率為95.12%。MRI診斷的39例眼眶神經(jīng)鞘瘤患者定性診斷正確的36例,定性診斷符合率為92.31%;定位診斷正確的37例,定位診斷符合率為94.87%。CT、MRI診斷眼眶海綿狀血管瘤的定性符合率和定位符合率差異均無統(tǒng)計(jì)學(xué)意義(Pgt;0.05),CT、MRI診斷眼眶神經(jīng)鞘瘤的定性符合率和定位符合率差異也均無統(tǒng)計(jì)學(xué)意義(Pgt;0.05)。結(jié)論CT、MRI在眼眶海綿狀血管瘤和眼眶神經(jīng)鞘瘤的影像學(xué)鑒別診斷中均具有非常重要的作用,二者的定性、定位診斷符合率均很高,具有很高的應(yīng)用價(jià)值。
CT;MRI;眼眶海綿狀血管瘤;眼眶神經(jīng)鞘瘤;影像學(xué)鑒別診斷
(ChinJLabDiagn,2017,21:1890)
眼眶海綿狀血管瘤與眼眶神經(jīng)鞘瘤都是臨床上常見的一種眼眶腫瘤,其中眼眶海綿狀血管瘤的臨床表現(xiàn)多為引起緩慢地、漸進(jìn)性單側(cè)眼球突出,眼眶海綿狀血管瘤患者的早期癥狀很難被發(fā)現(xiàn),患者也難以察覺,因此對(duì)患者的健康造成較大的威脅[1,2]。本文主要探討CT和MRI在眼眶海綿狀血管瘤和眼眶神經(jīng)鞘瘤的影像學(xué)鑒別診斷中的應(yīng)用價(jià)值和效果,具體報(bào)道如下。
1.1一般資料
選取我院2015年3月至2016年3月收治的經(jīng)CT診斷為眼眶海綿狀血管瘤患者38例(男20例,女18例)和眼眶神經(jīng)鞘瘤患者45例(男24例,女21例),經(jīng)MRI診斷為眼眶海綿狀血管瘤患者41例(男21例,女20例)和眼眶神經(jīng)鞘瘤患者39例(男19例,女20例)。CT診斷的患者中最低年齡18歲,最高年齡72歲,平均年齡(39.1±2.5)歲;MRI診斷的患者中最低年齡21歲,最高年齡73歲,平均年齡(41.2±2.3)歲。所有患者影像學(xué)診斷后均行手術(shù)并做病理學(xué)診斷。CT和MRI診斷的兩組患者在年齡、性別等一般資料方面無顯著性差異,具有可比性。
1.2方法
磁共振成像掃描采用Siemens Magnetom Skyra3.0T超導(dǎo)核磁共振儀,圓形極化相控陣顱腦表面線圈,掃描參數(shù):T1W(TR169ms,TR2.5ms)、T2W(TR3500ms,TE69ms),F(xiàn)OV340 mm×340 mm,層間距0.4 mm,層厚4 mm,激勵(lì)2次。所有患者均進(jìn)行增強(qiáng)掃描,造影劑為軋噴酸葡胺(廣州康臣藥業(yè)公司),靜脈給藥,注射后立即掃描。CT掃描根據(jù)患者的具體情況選擇合適的層面,部分行增強(qiáng)掃描,采用東芝TCT-80 A CT掃描儀,掃描參數(shù):層厚5 mm,層間距5 mm,矩陣512×512。增強(qiáng)對(duì)比劑采用泛影葡胺,靜脈給藥50-100 ml[3]。
1.3觀察指標(biāo)[4]
在患者的手術(shù)過程中觀察病灶的位置,將影像學(xué)診斷結(jié)果與之比較,判斷是否正確。對(duì)患者的病灶組織進(jìn)行病理學(xué)檢驗(yàn),將影像學(xué)診斷結(jié)果與病理結(jié)果比較,判斷是否正確。
1.4統(tǒng)計(jì)學(xué)方法
對(duì)所得數(shù)據(jù)資料全部采用SPSS18.0統(tǒng)計(jì)軟件進(jìn)行統(tǒng)計(jì)分析,計(jì)數(shù)資料采用卡方檢驗(yàn),計(jì)量資料采用t檢驗(yàn)。當(dāng)Plt;0.05時(shí),差異有統(tǒng)計(jì)學(xué)意義。
2.1CT、MRI診斷眼眶海綿狀血管瘤的定位、定性診斷符合率比較CT診斷的38例眼眶海綿狀血管瘤患者定性診斷正確的31例,定性診斷符合率為81.58%;定位診斷正確33例,定位診斷符合率為86.84%。MRI診斷的41例眼眶海綿狀血管瘤患者定性診斷正確的38例,定性診斷符合率為92.68%;定位診斷正確39例,定位診斷符合率為95.12%,見表1,圖1,圖2。差異均無統(tǒng)計(jì)學(xué)意義(Pgt;0.05)。
表1 CT、MRI診斷眼眶海綿狀血管瘤的定位、定性診斷符合率比較
2.2CT、MRI診斷眼眶神經(jīng)鞘瘤的定位、定性診斷符合率比較CT診斷的45例眼眶神經(jīng)鞘瘤患者定性診斷正確的39例,定性診斷符合率為86.67%;定位診斷正確37例,定位診斷符合率82.22%。MRI診斷的39例眼眶神經(jīng)鞘瘤患者定性診斷正確的36例,定性診斷符合率為92.31%;定位診斷正確的37例,定位診斷符合率為94.87%。見表2。
表2 CT、MRI診斷眼眶神經(jīng)鞘瘤的定位、定性診斷符合率比較
眼眶海綿狀血管瘤和眼眶神經(jīng)鞘瘤都是臨床上常見的一種眼眶腫瘤,其中眼眶神經(jīng)鞘瘤在眼眶腫瘤中的發(fā)病率較高,對(duì)患者的身體健康帶來嚴(yán)重的影響,嚴(yán)重的甚至?xí){到患者的生命[5,6]。眼眶神經(jīng)鞘瘤在眼眶腫瘤中的發(fā)病率高達(dá)20%左右,相關(guān)報(bào)道顯示,神經(jīng)源腫瘤分類中,神經(jīng)鞘瘤占比位居第一位[7]。CT的掃描平面分為矢狀、水平和冠狀三個(gè)方向,臨床掃描時(shí)可根據(jù)患者的具體情況選擇其他位置層面進(jìn)行掃描[8]。磁共振成像將某些特定的原子核放置在磁場(chǎng)內(nèi),由射頻脈沖對(duì)其激勵(lì),讓原子核吸收后釋放出脈沖信號(hào),從而形成體層像[9,10]。由于兩種疾病的早期癥狀都不是很明顯,患者自身難以察覺得到,普通的檢查手段誤診率也較高,故而CT和MRI這兩種較為先進(jìn)的影像學(xué)檢查手段在這兩種疾病的鑒別診斷中發(fā)揮著巨大的作用[11,12]。
圖1眼眶海綿狀血管瘤CT診斷圖2眼眶海綿狀血管瘤MRI診斷
本研究顯示T診斷的38例眼眶海綿狀血管瘤患者定性診斷正確的31例,定性診斷符合率為81.58%;定位診斷正確33例,定位診斷符合率為86.84%。CT診斷的45例眼眶神經(jīng)鞘瘤患者定性診斷正確的39例,定性診斷符合率為86.67%;定位診斷正確37例,定位診斷符合率82.22%。MRI診斷的41例眼眶海綿狀血管瘤患者定性診斷正確的38例,定性診斷符合率為92.68%;定位診斷正確39例,定位診斷符合率為95.12%。MRI診斷的39例眼眶神經(jīng)鞘瘤患者定性診斷正確的36例,定性診斷符合率為92.31%;定位診斷正確的37例,定位診斷符合率為94.87%。CT、MRI診斷眼眶海綿狀血管瘤的定性符合率和定位符合率差異均無統(tǒng)計(jì)學(xué)意義(Pgt;0.05),CT、MRI診斷眼眶神經(jīng)鞘瘤的定性符合率和定位符合率差異也均無統(tǒng)計(jì)學(xué)意義(Pgt;0.05)。通過本文的研究結(jié)果可以看出,CT和MRI在診斷眼眶海綿狀血管瘤和眼眶神經(jīng)鞘瘤中的定性診斷符合率和定位診斷符合率均無顯著的差異,且二者的診斷符合率均較高,說明其在眼眶海綿狀血管瘤和眼眶神經(jīng)鞘瘤的鑒別診斷中應(yīng)用價(jià)值高[13]。
相關(guān)臨床報(bào)道認(rèn)為[14,15],雖然CT和MRI在診斷眼眶海綿狀血管瘤和神經(jīng)鞘瘤的符合率無顯著差異,但在掃描特點(diǎn)上來看,MRI和CT的增強(qiáng)掃描特點(diǎn)基本一致,作出的定性診斷結(jié)果基本一致,而在神經(jīng)鞘瘤的診斷上,MRI優(yōu)于CT,因?yàn)镸RI可以更加清晰的顯示腫瘤的位置、邊界以及形狀。
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CTandMRIstudyondifferentialdiagnosisoforbitalcavernoushemangiomaandorbitalschwannomaimage
LIJin-xing,GUOQing-huan,ZHANGLin-chang*.
(TheFifthCentralHospitalofTianjin,Tcanjin300451,China)
ObjectiveTo study the CT and MRI value in the differential diagnosis of orbital cavernous hemangioma and orbital schwannoma image.Methodsin our hospital from March 2015 to March 2016 were diagnosed by CT in 45 cases and 38 cases of orbital schwannoma in patients with orbital cavernous hemangioma,39 cases diagnosed by MRI and 41 cases of orbital schwannoma in patients with orbital cavernous hemangioma.All the patients underwent the differential diagnosis of tumors,mainly divided into qualitative diagnostic and positioning diagnosis and qualitative diagnosis is consistent with the imaging diagnosis and pathological diagnosis; localization diagnosis is the imaging diagnosis and surgical positioning results.Calculation of CT,MRI qualitative,positioning diagnostic compliance rate.ResultsCT diagnosis of 38 cases of orbital cavernous hemangioma in patients with qualitative diagnosis of 31 cases,the rate of qualitative diagnosis was 81.58%;33 cases were diagnosed correctly,the positioning accuracy of the diagnosis was 86.84%.CT diagnosis of 45 cases of orbital schwannoma were qualitatively correct diagnosis in 39 cases,diagnosis coincidence rate was 86.67%; 37 cases were diagnosed correctly positioning,positioning diagnosis rate 82.22%.MRI diagnosis of 41 cases of orbital cavernous hemangioma of the qualitative diagnosis of 38 cases,the rate of qualitative diagnosis was 92.68%; 39 cases were diagnosed correctly,the positioning accuracy of the diagnosis was 95.12%.MRI diagnosis of 39 cases of orbital schwannoma were qualitatively correct diagnosis in 36 cases,diagnosis coincidence rate was 92.31%; 37 cases of correct diagnosis,diagnosis coincidence rate is 94.87%.CT MRI,the qualitative diagnosis of orbital cavernous hemangioma coincidence rate and coincidence rate of localization was no statistically significant difference (Pgt;0.05),CT MRI,the qualitative diagnosis of orbital neurilemoma coincidence rate and localization coincidence rate differences were not statistically significant(Pgt;0.05).ConclusionCT and MRI in orbital cavernous hemangioma and orbital neurilemoma were imaging plays a very important role in the differential diagnosis,the coincidence rate is very high,the two qualitative diagnosis,and has high application value.
CT;MRI;cavernous hemangioma;orbital schwannoma;differential diagnosis imaging
*通訊作者
1007-4287(2017)11-1890-04
R739.8
A
張林昌,男,51歲,主任醫(yī)師,研究方向,眼科疾病。
2016-11-17)