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The role of acupoint embedding combined with clomiphene in the treatment of polycystic ovary syndrome

2018-01-25 04:50:13
TMR Non-Drug Therapy 2018年4期

Polycystic ovary syndrome(PCOS)is a comprehensive syndrome with clinical features of low menstruation or amenorrhea,obesity,crinosity,and infertility as a result of endocrine disturbance and metabolic disorder[1].Its pathomechanism is extremely complex,e.g.,heredity,internal secretion,immunity,and metabolism.Furthermore,it is considered as the important dangerous factors of many serious diseases such as type 2 diabetes,cardiovascular diseases,hypertension syndrome of pregnancy and endometrial carcinoma,which make it go beyond the range of gynecology and raise the attention worldwide.

The etiology of PCOS remains poorly understood.At present,there is no therapeutic cure method and its management remains unsatisfactory because it mainly relies on the management of symptoms[2].Among which clomiphene is known as the first-line medicine in the medical treatment of PCOS.Unfortunately,about 20%of the patients are unresponsive to clomiphene and it usually leads to the occurrence of side effects,e.g.,ovarian enlargement,headache and blurred vision[3].

According to its clinical features,traditional Chinese medicine distributes it to the scope of“l(fā)ow menstruation”,“amenorrhea”or“infertility”.In the theory of Chinese medicine,kidney deficiency is the root and phlegm-damp is the surface.Strengthening kidney and removing phlegm-damp is considered as the fundamental method of treatment PCOS[4].In the field of traditional Chinese medicine,acupuncture therapy occupies an irreplaceable position.The earliest monograph of acupuncture in China is inZhenjiujiayijing(215-282 A.D.Jin Dynasty).However,through long-term clinical research,doctors have found that the effect of simple acupuncture on chronic diseases is difficult to sustain.Therefore it is necessary to"retain needles"to enhance and consolidate their curative effects[5-8].Acupoint embedding can further stimulate acupuncture points through the catgut suture for a long time,to reduce the number of outpatients as well as save the patient's time and cost.

To read more about the role of acupoint embedding combined with clomiphene in the treatment of PCOS,see this article please:effects of acupoint embedding combined with clomiphene in patients with polycystic ovary syndrome:a randomized controlled trial.Link:https://www.tmrjournals.com/ndt/EN/abstract/abstract367.shtml

1. Lizneva D,Suturina L,Walker W,et al.Criteria,prevalence,and phenotypes of polycystic ovary syndrome.Fertile Steril 2016,106:6-15.

2. Walters KA,Gilchrist RB,Ledger WL,et al.New perspectives on the pathogenesis of PCOS:neuroendocrine origins.Trends Endocrinol Metab 2018.[Epub ahead of print]

3. Legro RS,Brzyski RG,Diamond MP,et al.Letrozole versus clomiphene for infertility in the polycystic ovary syndrome.N Engl J Med 2014:371:119-129.

4. Zhang YL,Pan W,Wang YJ.The research progress in the study of etiology and pathogenesis of polycystic ovary syndrome.J Basic Chin Med 2016,22:1004-1006.

5. Wu JM,Zhuo YY,Zhong YL,et al.The acupuncture method of transfer the Ren and Du meridian combined with acupoint embedding therapy to treat with polycystic ovary syndrome infertility.Jilin J Tradit Chin Med 2014,34:526-529.

6. Dong J,Wang C.Clinical observation on the treatment of polycystic ovary syndrome by acupoint embedding.CJGMCM 2016,31:381-382.

7. Gong XH.The treatment of phlegm-dampened polycystic ovary syndrome by acupoint embedding method.ChinArchives Tradit Chin Med 2012,30:2001-2002.

8. Feng SJ,Yang J.Clinical progress in the treatment of polycystic ovary syndrome by acupoint embedding.World Latest Med Information 2018,18:102-105.

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