朱青娟

[摘要] 目的 探究宮腔鏡子宮內(nèi)膜微創(chuàng)術(shù)對(duì)患者生殖內(nèi)分泌及子宮內(nèi)膜容受性的影響。 方法 方便選取2016年1月—2018年12月在該院接受宮腔鏡子宮內(nèi)膜微創(chuàng)術(shù)治療的82例患者作為研究對(duì)象，對(duì)其術(shù)前術(shù)后的生殖內(nèi)分泌和子宮內(nèi)膜容受性進(jìn)行觀察分析。結(jié)果 觀察患者術(shù)前術(shù)后的生殖內(nèi)分泌相關(guān)指標(biāo)發(fā)現(xiàn)，術(shù)后的P（孕酮）（4.91±0.16）μg/L高于術(shù)前（4.30±0.24）μg/L，差異有統(tǒng)計(jì)學(xué)意義（t=5.980，P=0.000），術(shù)后E2（雌二醇）（230.98±17.03）ng/L高于術(shù)前（197.03±18.95）ng/L，差異有統(tǒng)計(jì)學(xué)意義（t=3.770，P=0.000），術(shù)后FSH（促卵泡激素）（9.12±0.33）IU/L高于術(shù)前（7.03±0.43）IU/L，差異有統(tǒng)計(jì)學(xué)意義（t=10.910，P=0.000），術(shù)后LH（血清促黃體生成素）（21.87±0.90）IU/L高于術(shù)前（17.99±0.87）IU/L，差異有統(tǒng)計(jì)學(xué)意義（t=8.770，P=0.000）。觀察患者術(shù)前術(shù)后子宮內(nèi)膜容受性相關(guān)指標(biāo)發(fā)現(xiàn)，術(shù)后的子宮內(nèi)膜厚度（13.01±0.76）mm較厚于術(shù)前（8.71±0.89）mm，差異有統(tǒng)計(jì)學(xué)意義（t=10.390，P=0.000），術(shù)后的PI（搏動(dòng)指數(shù)）（0.81±0.04）低于術(shù)前（0.90±0.05），差異有統(tǒng)計(jì)學(xué)意義（t=4.420，P=0.000），術(shù)后RI（內(nèi)膜動(dòng)脈阻力指數(shù)）（2.21±0.13）低于術(shù)前（3.10±0.16），差異有統(tǒng)計(jì)學(xué)意義（t=12.210，P=0.000）。 結(jié)論 通過探究宮腔鏡子宮內(nèi)膜微創(chuàng)術(shù)對(duì)患者生殖內(nèi)分泌及子宮內(nèi)膜容受性的影響發(fā)現(xiàn)良好，可有效的對(duì)患者的生殖內(nèi)分泌水平和子宮內(nèi)膜容受性進(jìn)行提升和改善，臨床應(yīng)用價(jià)值較高。

[關(guān)鍵詞] 宮腔鏡子宮內(nèi)膜微創(chuàng)術(shù);生殖內(nèi)分泌;子宮內(nèi)膜容受性

[Abstarct] Objective To explore the effect of hysteroscopic endometrial minimally invasive surgery on reproductive endocrine and endometrial receptivity. Methods Convenient select from January 2016 to December 2018， 82 patients who underwent hysteroscopic endometrial minimally invasive surgery in the hospital were enrolled as study subjects. The reproductive endocrine and endometrial receptivity before and after operation were observed and analyzed. Results? Observing the reproductive endocrine-related indicators of patients before and after operation， it was found that the postoperative P （progesterone）（4.91±0.16）μg/Lwas higher than that before surgery （4.30±0.24 ）μg/L，the difference was statistically significant （t=5.980， P=0.000）， postoperative E2 （estradiol） （230.98±17.03）ng/L is higher than preoperative （197.03±18.95）ng/L，the difference was statistically significant （t=3.770， P=0.000）， and FSH （follicle-stimulating hormone） （9.12±0.33） IU/Lwas higher than before surgery（7.03±0.43）IU/L，the difference was statistically significant（t=10.910， P=0.000）， postoperative LH （serum luteinizing hormone） （21.87±0.90） IU/Lwas higher than before surgery （17.99±0.87） IU/L，the difference was statistically significant（t=8.770，P=0.000）. Observing the related indexes of endometrial receptivity before and after the operation， the thickness of the endometrium after operation （13.01±0.76） mmwas thicker than that before operation （8.71±0.89） mm，the difference was statistically significant（t=10.390， P=0.000）， Postoperative PI （pulsation index） （0.81±0.04） was lower than preoperative （0.90±0.05），the difference was statistically significant（t=4.420， P=0.000）， postoperative RI （endometrial arterial resistance index） （2.21±0.13） was lower than before（3.10±0.16），the difference was statistically significant（t=12.210， P=0.000）. Conclusion By exploring the effect of endometrial minimally invasive hysteroscopy on the reproductive endocrine and endometrial receptivity of patients， we found that it is good， and can effectively improve the reproductive endocrine level and endometrial receptivity of patients. It has high clinical value.