吳育羅+黃冠軍

[摘要] 惡性黑色素瘤是一種惡性程度極高且發(fā)病率持續(xù)增長的腫瘤，對術(shù)后輔助放、化療不敏感，預(yù)后較差。研究發(fā)現(xiàn)，惡性黑色素瘤為免疫原性較高的腫瘤，因此，腫瘤生物治療得到廣泛應(yīng)用，細胞免疫治療已成為惡性黑色素瘤個體化綜合治療的重要組成部分及研究熱點。本文就惡性黑色素瘤的細胞免疫治療研究進展作一綜述。

[關(guān)鍵詞] 惡性黑色素瘤；細胞免疫治療；研究進展

[中圖分類號] R730.5 [文獻標(biāo)識碼] A [文章編號] 1674-4721（2014）09（c）-0194-03

Research progress on cell immunotherapy of malignant melanoma

WU Yu-luo HUANG Guan-jun

Cancer Prevention and Control Center，Affiliated Zhanjiang Cental People′s Hospital of Guangdong Medical College，Zhanjiang 524037，China

[Abstract] Malignant melanoma is among the most lethal of the cutaneous neoplasms，and the incidence of it has been rising over the past few decades Malignant melanoma is not sensitive to chemotherapy and radiation therapy，and has a poor prognosis.Studies found that malignant melanoma shows a high immunogenicity，therefore，tumor biologic therapy is widely applicated.Cell immunotherapy has become an important part of individualizedly systematic treatment and research hot spot.In this paper，research progress on cell immunotherapy of malignant melanoma was reviewed.

[Key words] Malignant melanoma；Cell immunotherapy；Research progress

惡性黑色素瘤的細胞免疫治療研究進展

吳育羅 黃冠軍

廣東醫(yī)學(xué)院附屬湛江中心人民醫(yī)院腫瘤防治中心，廣東湛江 524037

[摘要] 惡性黑色素瘤是一種惡性程度極高且發(fā)病率持續(xù)增長的腫瘤，對術(shù)后輔助放、化療不敏感，預(yù)后較差。研究發(fā)現(xiàn)，惡性黑色素瘤為免疫原性較高的腫瘤，因此，腫瘤生物治療得到廣泛應(yīng)用，細胞免疫治療已成為惡性黑色素瘤個體化綜合治療的重要組成部分及研究熱點。本文就惡性黑色素瘤的細胞免疫治療研究進展作一綜述。

[關(guān)鍵詞] 惡性黑色素瘤；細胞免疫治療；研究進展

[中圖分類號] R730.5 [文獻標(biāo)識碼] A [文章編號] 1674-4721（2014）09（c）-0194-03

Research progress on cell immunotherapy of malignant melanoma

WU Yu-luo HUANG Guan-jun

Cancer Prevention and Control Center，Affiliated Zhanjiang Cental People′s Hospital of Guangdong Medical College，Zhanjiang 524037，China

[Abstract] Malignant melanoma is among the most lethal of the cutaneous neoplasms，and the incidence of it has been rising over the past few decades Malignant melanoma is not sensitive to chemotherapy and radiation therapy，and has a poor prognosis.Studies found that malignant melanoma shows a high immunogenicity，therefore，tumor biologic therapy is widely applicated.Cell immunotherapy has become an important part of individualizedly systematic treatment and research hot spot.In this paper，research progress on cell immunotherapy of malignant melanoma was reviewed.

[Key words] Malignant melanoma；Cell immunotherapy；Research progressendprint