孫學(xué)榮
[摘要] 目的 研究修正性鼻內(nèi)鏡手術(shù)治療復(fù)發(fā)性慢性鼻-鼻竇炎的臨床效果。 方法 該次方便選取2017年2月—2019年10月收治的70例復(fù)發(fā)性慢性鼻-鼻竇炎患者展開(kāi)研究,按照隨機(jī)數(shù)字表法分為兩組,對(duì)照組35例實(shí)施常規(guī)保守治療,觀察組35例采用修正性鼻內(nèi)鏡手術(shù)治療。將兩組的臨床癥狀評(píng)分、鼻腔氣道阻力、嗅覺(jué)功能評(píng)分、臨床效果、并發(fā)癥發(fā)生率進(jìn)行比對(duì)。結(jié)果 觀察組患者治療后的臨床癥狀評(píng)分(5.98±1.34)分、鼻腔氣道阻力(1.19±0.16)kPa/(s·L)均低于對(duì)照組,治療后的嗅覺(jué)功能評(píng)分(4.61±0.75)分高于對(duì)照組,差異有統(tǒng)計(jì)學(xué)意義(t=11.679、21.526、7.416,P<0.05);觀察組患者的臨床總有效率(91.43%)高于對(duì)照組(65.71%),并發(fā)癥發(fā)生率(5.71%)低于對(duì)照組(75.71%),差異有統(tǒng)計(jì)學(xué)意義(χ2=6.873、5.285,P=0.009、0.022)。結(jié)論 對(duì)復(fù)發(fā)性慢性鼻-鼻竇炎患者采用修正性鼻內(nèi)鏡手術(shù)治療安全有效,有助于臨床癥狀、嗅覺(jué)功能的改善,具有較高的臨床應(yīng)用價(jià)值。
[關(guān)鍵詞] 復(fù)發(fā)性慢性鼻-鼻竇炎;修正性鼻內(nèi)鏡手術(shù);并發(fā)癥
[中圖分類(lèi)號(hào)] R765.9 ? ? ? ? ?[文獻(xiàn)標(biāo)識(shí)碼] A ? ? ? ? ?[文章編號(hào)] 1674-0742(2020)11(a)-0050-03
Clinical Review Value of Corrective Endoscopic Sinus Surgery for the Treatment of Recurrent Chronic Rhinosinusitis
SUN Xue-rong
Department of Otolaryngology, Pizhou Hospital of Traditional Chinese Medicine, Pizhou, Jiangsu Province, 221300 China
[Abstract] Objective To study the clinical effect of modified endoscopic sinus surgery in the treatment of recurrent chronic rhinosinusitis. Methods This study conveniently selected 70 patients with recurrent chronic rhinosinusitis who were admitted from February 2017 to October 2019. They were divided into two groups according to the random number table method. The control group 35 received conventional conservative treatment, and the observation group of 35 cases were treated with modified endoscopic sinus surgery. The clinical symptom score, nasal airway resistance, olfactory function score, clinical effect, and complication rate of the two groups were compared. Results The clinical symptom score (5.98±1.34)points and nasal airway resistance (1.19±0.16) kPa/(s·L) of the observation group after treatment were lower than those of the control group, and the olfactory function score(4.61±0.75)points after treatment was higher than that of the control group, the difference was statistically significant(t=11.679, 21.526, 7.416, P<0.05); the total clinical effective rate (91.43)% of the observation group was higher than that of the control group(65.71%), and the complication rate (5.71)% lower than the control group(25.71%), the difference was statistically significant(χ2=6.873, 5.285, P=0.009, 0.022). Conclusion Corrective endoscopic sinus surgery is safe and effective for patients with recurrent chronic rhinosinusitis. It is helpful to improve clinical symptoms and olfactory function, and has high clinical application value.
[Key words] Recurrent chronic rhinosinusitis; Revision endoscopic sinus surgery; Complications
觀察組患者的并發(fā)癥發(fā)生率為5.71%,與對(duì)照組數(shù)據(jù)相比較,差異有統(tǒng)計(jì)學(xué)意義(P<0.05)。見(jiàn)表4。
3 ?討論
慢性鼻-鼻竇炎的病因主要為急性鼻竇炎治療不當(dāng)、鼻腔內(nèi)阻塞性疾病、外傷、感染等,以膿涕、鼻塞、嗅覺(jué)障礙、頭痛等為主要臨床癥狀[3-4],會(huì)對(duì)患者的生活質(zhì)量產(chǎn)生影響,促使呼吸道感染癥狀加重。復(fù)發(fā)性慢性鼻-鼻竇炎的病程長(zhǎng)且遷延不愈,采用常規(guī)保守治療后仍易復(fù)發(fā),效果不太理想。
修正性鼻內(nèi)鏡手術(shù)是指對(duì)復(fù)發(fā)性慢性鼻-鼻竇炎患者進(jìn)行再次、多次手術(shù)。修正性鼻內(nèi)鏡手術(shù)能夠?qū)⒒颊弑乔粌?nèi)的息肉切除,將竇口鼻道復(fù)合體堵塞、引流問(wèn)題解決,促使患者鼻竇、鼻腔內(nèi)部保持暢通[5-6],有助于患者鼻竇通氣功能、引流功能的恢復(fù)[7];另外修正性鼻內(nèi)鏡手術(shù)屬于微創(chuàng)手術(shù),通過(guò)鼻內(nèi)鏡進(jìn)行手術(shù)操作,其分辨率較高,可顯示鼻部?jī)?nèi)情況,并通過(guò)變換視覺(jué)角度可進(jìn)行更精準(zhǔn)的操作,能夠減少對(duì)鼻中隔、中鼻甲以及鼻黏膜的損傷[8],將鼻竇解剖組織有效保留,可促進(jìn)并發(fā)癥發(fā)生率的降低[9-10],有助于患者術(shù)后康復(fù)速度的加快;通過(guò)切除息肉,可防止術(shù)后炎癥持續(xù)發(fā)展,降低復(fù)發(fā)率;且術(shù)前、術(shù)后的抗感染、抗炎處理、鼻腔沖洗等措施能夠有效鞏固手術(shù)效果[11],有助于黏膜水腫癥狀的減輕和纖毛功能的恢復(fù),能夠延緩息肉生長(zhǎng)速度以及復(fù)發(fā),促進(jìn)患者預(yù)后效果的改善。
該文研究數(shù)據(jù)顯示,觀察組患者治療后的臨床癥狀評(píng)分明顯下降,鼻腔氣道阻力下降,嗅覺(jué)功能評(píng)分升高,且臨床總有效率(91.43%)更高,并發(fā)癥發(fā)生率(5.71%)更低,較好地說(shuō)明了修正性鼻內(nèi)鏡手術(shù)的效果比常規(guī)保守治療更加顯著,這是因?yàn)樵撔g(shù)式能直接切除病變,在短時(shí)間內(nèi)改善臨床癥狀,并能夠降低復(fù)發(fā)情情況的發(fā)生,取得較好的預(yù)后效果。侯樂(lè)[12]的研究數(shù)據(jù)顯示,觀察組患者的臨床總有效率、并發(fā)癥發(fā)生率分別為95.5%、4.5%,均優(yōu)于對(duì)照組,證明了修正性鼻內(nèi)鏡手術(shù)具有較高的臨床應(yīng)用價(jià)值,且所得數(shù)據(jù)與該文相差不大,側(cè)面證實(shí)了該次研究結(jié)論真實(shí)可靠。
綜上所述,修正性鼻內(nèi)鏡手術(shù)應(yīng)用于復(fù)發(fā)性慢性鼻-鼻竇炎患者中的臨床價(jià)值高,可有效減輕臨床癥狀,安全有效。
[參考文獻(xiàn)]
[1] ?韓琳,唐靜.克拉霉素應(yīng)用于復(fù)發(fā)性慢性鼻-鼻竇炎患者修正性鼻內(nèi)鏡手術(shù)后的臨床效果[J].臨床醫(yī)學(xué)研究與實(shí)踐,2019,4(32):106-108.
[2] ?李二樂(lè),陳鋒剛.鼻內(nèi)鏡修正性手術(shù)聯(lián)合中鼻甲切除治療難治性鼻-鼻竇炎的臨床效果[J].臨床醫(yī)學(xué)研究與實(shí)踐,2019,4(28):87-89.
[3] ?劉喜亮.修正性鼻內(nèi)鏡手術(shù)治療復(fù)發(fā)性鼻竇炎-鼻息肉的臨床效果[J].中外醫(yī)學(xué)研究,2019,17(26):139-140.
[4] ?楊朋.復(fù)發(fā)性鼻竇炎應(yīng)用修正性鼻內(nèi)鏡手術(shù)治療的臨床分析[J].航空航天醫(yī)學(xué)雜志,2019,30(8):961-963.
[5] ?Motohiko Suzuki,Yoshihisa Nakamura,Shinya Ozaki,et al.Repair of Orbital Floor Fracture With Modified Transnasal Endoscopic Approach Through Anterior Space to Nasolacrimal Duct[J].Journal of Craniofacial Surgery,2017,28(4):1.
[6] ?鄭明祥,湯偉,洪錦科.鼻內(nèi)鏡修正手術(shù)治療80例復(fù)發(fā)性鼻竇炎鼻息肉的臨床效果[J].江蘇醫(yī)藥,2019,45(4):426-428.
[7] ?茅金金.修正性鼻內(nèi)鏡手術(shù)治療復(fù)發(fā)性鼻竇炎鼻息肉的分析[J].當(dāng)代醫(yī)學(xué),2019,25(6):150-151.
[8] ?李珊,李大立.修正性鼻內(nèi)鏡手術(shù)治療復(fù)發(fā)性慢性鼻-鼻竇炎合并內(nèi)翻性乳頭狀瘤的臨床效果觀察[J].中華腫瘤防治雜志,2018,25(S1):21-22.
[9] ?洪海填,蔡河清.修正性鼻內(nèi)鏡手術(shù)治療復(fù)發(fā)性鼻竇炎鼻息肉的臨床效果[J].中外醫(yī)學(xué)研究,2018,16(17):56-58.
[10] ?陸雪,黃美響,肖楚志,等.修正性鼻內(nèi)鏡手術(shù)治療復(fù)發(fā)性慢性鼻-鼻竇炎的臨床分析[J].中國(guó)耳鼻咽喉顱底外科雜志,2017,23(3):271-274.
[11] ?陸小虎,李星玉,王平,等.修正性鼻內(nèi)鏡手術(shù)聯(lián)合克拉霉素治療復(fù)發(fā)性慢性鼻-鼻竇炎療效研究[J].檢驗(yàn)醫(yī)學(xué)與臨床,2016,13(13):1778-1780.
[12] ?侯樂(lè).修正性鼻內(nèi)鏡手術(shù)治療復(fù)發(fā)性慢性鼻-鼻竇炎患者的效果[J].中國(guó)民康醫(yī)學(xué),2018,30(15):71-72.
(收稿日期:2020-08-07)