田豐偉 孟和 孫志宏 杭曉敏 劉斌

摘 要：益生菌是指一類足量攝入后能對宿主健康水平產生有益影響的活微生物，具有優(yōu)良的生理功能，已成為國際食品生物工程領域的研究熱點。益生菌相關產品已成為國內外食品工業(yè)中一個飛速增長的領域，具有廣闊的市場前景和社會價值。益生菌及其相關產業(yè)發(fā)展的兩大核心是專利菌種和應用關鍵技術，在這兩方面我們受制于國外技術與產品。該研究針對我國益生菌產業(yè)發(fā)展中存在的亟待解決的關鍵性技術問題，通過益生菌篩選模型的構建與研究以及益生菌產業(yè)化關鍵技術的研究，開發(fā)具有特定功能性質的新型益生菌菌株，并對其功能進行基因定位；在產業(yè)化應用方面，著力研究益生菌的發(fā)酵培養(yǎng)、活性保持等關鍵技術，為益生菌的產業(yè)化應用提供關鍵技術支持。

關鍵詞：益生菌 基因組測序 菌粉 食品生物 益生菌菌株

Abstract：Probiotics refer to a class of live microorganisms that have beneficial impact on the health level of the host， which have good physiological function and become a research hotspot in the field of international food biotechnology. Probiotic products have become a rapidly growing field in the food industry both in china and abroad， which have a broad market prospect and social values. Proprietary species and application of key technologies are two core of probiotics and related industry development， we are subjected to foreign technology and products in both areas. This project for probiotics industry in China to be solved in the development of the key technical problems， through the construction and research of probiotic bacteria screening model and probiotics industrialization key technology research and development with specific functional properties of new probiotic strain， and gene location for its function； In industrial applications， focusing on the research of probiotic fermented culture， active， the key techniques such as the key technology for industrialization of probiotics and application support.

Key Words：Probiotic；Interaction；Genome Sequencing；Bacterial Powder

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