.臨床醫(yī)學(xué)圖像.

細(xì)胞性神經(jīng)鞘瘤

圖1 光學(xué)顯微鏡觀(guān)察所見(jiàn) HE染色 1a 細(xì)胞性神經(jīng)鞘瘤有包膜,Antoni A區(qū)明顯增多,腫瘤細(xì)胞密度較高 X100 1b 核分裂象易見(jiàn) X200Figure 1 Optical microscopy findings HE staining Cellular schwannoma is encapsulated and comsists mostly of Antoni A tissue,with increased cellularity(Panel 1a). X100 Mitoses are regularly seen(Panel 1b). X200

細(xì)胞性神經(jīng)鞘瘤是神經(jīng)鞘瘤的一種亞型,好發(fā)于女性.腫瘤主要或僅由Antoni A型區(qū)組成,未見(jiàn)Verocay小體,有包膜,血管壁透明樣變明顯.組織學(xué)形態(tài)可見(jiàn)腫瘤組織主要由緊密束狀、席紋狀或非特殊排列的梭形細(xì)胞組成(圖1a),漩渦狀結(jié)構(gòu)顯著但不常見(jiàn),包膜內(nèi)或包膜下可見(jiàn)淋巴細(xì)胞聚集和數(shù)量不等的富含脂質(zhì)組織細(xì)胞;梭形細(xì)胞胞質(zhì)呈嗜酸性,胞核呈梭形或卵圓形、染色質(zhì)深染,輕度多形性,核分裂象易見(jiàn)(圖1b).免疫表型和超微結(jié)構(gòu)與分化良好的神經(jīng)鞘瘤無(wú)差異.

(天津市環(huán)湖醫(yī)院病理科閻曉玲供稿)

Cellular schwannoma

YAN Xiao?ling
Department of Pathology,Tianjin Huanhu Hospital,Tianjin 300350,China(Email:ll934065@126.com)

10.3969/j.issn.1672?6731.2017.07.014