·臨床醫(yī)學(xué)圖像·
腦膜黑色素瘤
圖1 光學(xué)顯微鏡觀察所見(jiàn) HE染色 1a 腫瘤細(xì)胞呈巢狀或片狀排列,胞核呈空泡狀,核仁明顯,核分裂象易見(jiàn) ×400 1b腫瘤組織侵犯大腦皮質(zhì) ×100Figure 1 Optical microscopy findings HE staining The tumor cells were arranged in nest or sheet,with large vesicular nuclei,prominent nucleoli and brisk mitotic activity(Panel 1a). ×400 Tumor cells invaded the cerebral cortex(Panel 1b). ×100
腦膜黑色素瘤是一種源于軟腦膜黑色素細(xì)胞的惡性腫瘤,呈孤立性占位效應(yīng)、浸潤(rùn)性生長(zhǎng)。原發(fā)性腦膜黑色素瘤組織學(xué)形態(tài)類似其他部位黑色素瘤,間變性梭形或上皮樣腫瘤細(xì)胞呈疏松巢狀或片狀結(jié)構(gòu),胞質(zhì)內(nèi)富含數(shù)目不等的黑色素,部分腫瘤細(xì)胞為含奇異核的大細(xì)胞,核分裂象多見(jiàn),異型性明顯,核仁較大(圖1a);其余腫瘤細(xì)胞密度較高,異型性不明顯,常見(jiàn)侵犯周圍腦組織(圖1b)和凝固性壞死。
(天津市環(huán)湖醫(yī)院病理科閻曉玲供稿)
Meningeal melanoma
YAN Xiao?ling
Department of Pathology,Tianjin Huanhu Hospital,Tianjin 300350,China(Email:ll934065@126.com)
10.3969/j.issn.1672?6731.2017.05.016