吳偉琳
【摘要】 目的 評(píng)價(jià)糖尿病視網(wǎng)膜病變采用激光光凝術(shù)治療的臨床效果。方法 94例糖尿病視網(wǎng)膜病變患者, 隨機(jī)分為實(shí)驗(yàn)組和對(duì)照組, 每組47例。對(duì)照組患者采用內(nèi)科基礎(chǔ)治療, 實(shí)驗(yàn)組患者在對(duì)照組的治療基礎(chǔ)上聯(lián)合激光光凝術(shù)治療。比較兩組患者臨床療效以及治療前后臨床指標(biāo)[空腹血糖(FBG)、餐后2 h血糖(2 h PG)、紅細(xì)胞壓積、糖化血紅蛋白(HbA1c)、全血粘度]水平。結(jié)果 實(shí)驗(yàn)組患者治療總有效率89.36%高于對(duì)照組的61.70%, 差異具有統(tǒng)計(jì)學(xué)意義(P<0.05)。治療后, 兩組患者FBG、2 h PG、紅細(xì)胞壓積、HbA1c、全血粘度水平均優(yōu)于本組治療前, 差異具有統(tǒng)計(jì)學(xué)意義(P<0.05);但兩組比較, 差異無統(tǒng)計(jì)學(xué)意義(P>0.05)。結(jié)論 激光光凝術(shù)在糖尿病視網(wǎng)膜病變患者中具有良好的應(yīng)用效果, 能夠有效改善患者的視力水平, 值得推廣。
【關(guān)鍵詞】 糖尿病視網(wǎng)膜病變;激光光凝術(shù);臨床療效
DOI:10.14163/j.cnki.11-5547/r.2020.15.012
Clinical effect of laser photocoagulation on diabetic retinopathy? ?WU Wei-lin. Dalian Fifth Peoples Hospital, Dalian 116001, China
【Abstract】 Objective? ?To evaluate the clinical effect of laser photocoagulation on diabetic retinopathy. Methods? ?A total of 94 diabetic retinopathy patients were randomly divided into experimental group and control group, with 47 cases in each group. The control group received by basic medical therapy, and the experimental group received laser photocoagulation on the basis of the control group. The clinical effect, and clinical indexes [fasting blood glucose (FBG), 2 h postprandial glucose (2 h PG), hematocrit, glycosylated hemoglobin (HbA1c), whole blood viscosity] before and after treatment were compared between the two groups. Results? ?The total effective rate of treatment 89.36% of the experimental group was higher than that of the control group 61.70%, and the difference was statistically significant (P<0.05). After treatment, FBG, 2 h PG, hematocrit, HbA1c, whole blood viscosity of the two groups were better than those before treatment, and the? difference was statistically significant (P<0.05). But there was no statistically significant between the two groups (P>0.05). Conclusion? ?Laser photocoagulation has a good application effect in diabetic retinopathy patients, which can effectively improve the vision level of patients. It is worth promoting.
【Key words】 Diabetic retinopathy; Laser photocoagulation; Clinical effect
臨床治療糖尿病視網(wǎng)膜病變的常用方法有藥物、冷凝、激光、玻璃體切割術(shù)等手段, 藥物主要是為了控制血糖, 但不能從根本上改善視力水平[1], 激光光凝術(shù)是目前針對(duì)糖尿病視網(wǎng)膜病變患者應(yīng)用最為廣泛的一種技術(shù)[2, 3]。本院在對(duì)患者進(jìn)行常規(guī)用藥的基礎(chǔ)上聯(lián)合激光光凝術(shù)治療, 取得了良好的臨床效果, 現(xiàn)報(bào)告如下。
1 資料與方法
1. 1 一般資料 選取2018年5月~2019年8月本院收治的94例糖尿病視網(wǎng)膜病變患者, 所有患者均符合《實(shí)用眼科學(xué)》中提到的相關(guān)診斷標(biāo)準(zhǔn)[2], 單眼發(fā)病, 自愿簽署知情同意書, 眼底檢查發(fā)現(xiàn)患者伴有出血、黃斑水腫、硬性滲出等表現(xiàn)。排除妊娠哺乳期女性、合并其他眼科疾病、對(duì)研究藥物過敏、肝腎功能異常、最近3個(gè)月內(nèi)接受過相關(guān)治療的患者。將所有患者隨機(jī)分為實(shí)驗(yàn)組和對(duì)照組, 每組47例。實(shí)驗(yàn)組男27例, 女20例;年齡45~78歲, 平均年齡(60.72±5.77)歲;左眼發(fā)病18例, 右眼發(fā)病29例;糖尿病病程3~27年, 平均糖尿病病程(16.28±4.43)年;合并癥:27例高血