Ed Hurt,et al.

Ribosome production is vital for every cell,and failure causes human diseases.It is driven by～200 assembly factors functioning along an ordered pathway from the nucleolus to the cytoplasm.Structural snapshots of biogenesis intermediates from the earliest 90S pre-ribosomes to mature 40S subunits unravel the mechanisms of small ribosome synthesis.To view this SnapShot,open or download the PDF.