Estimates of Funding for Various Research, Condition, and Disease Categories (RCDC) displays the annual support level for various research, condition, and disease categories based on grants, contracts, and other funding mechanisms used across the National Institutes of Health (NIH).

At the request of Congress, the NIH embarked on a process to provide better consistency and transparency in the reporting of its funded research. This new process,implemented in 2008 through the RCDC system, uses sophisticated text data mining (categorizing and clustering using words and multiword phrases) in conjunction with NIH-wide definitions used to match projects to categories. The definitions are a list of terms and concepts selected by NIH scientific experts to define a research category. The research category levels represent the NIH’s best estimates based on the category definitions.

The NIH does not expressly budget by category. The annual estimates reflect amounts that change as a result of science, actual research projects funded, and the NIH budget. The research categories are not mutually exclusive. Individual research projects can be included in multiple categories so amounts depicted within each column of this table do not add up to 100 percent of NIH-funded research.

The Research Portfolio Online Reporting Tools (RePORT)Website provides a central point of access to reports,data, and analyses of NIH research. In addition to carrying out its scientific mission, NIH exemplifies and promotes the highest level of public accountability. To that end, the RePORT provides access to reports, data,and analyses of NIH research activities, including information on NIH expenditures and the results of NIH-supported research.

NIH funding for disease categories related to neurodegenerative disease (excluding Alzheimer’s disease and Pakinson’s disease), Alzheimer’s disease and Pakinson’s disease in the RePORT are shown in Tables 1-3.

Table 1 NIH funding for neurodegenerative disease in 2010 (Selected, with total cost over $500 000, excluding Alzheimer’s disease and Pakinson’s disease)

5RC1AR058738-02 DELINEATING FACTORS TO CONTROL DIFFERENTIATION OF SKIN DERIVED PRECURSOR CELLS 5RC1AG035878-02 DIET AND EXERCISE (DE)PROGRAM FOR ALZHEIMER PREVENTION 2R56NS036630-10 GENETIC EPIDEMIOLOGY OF PARKINSON'S DISEASE 2 SCHULTZ, PETER G SCRIPPS RESEARCH INSTITUTE 2 COLE, GREGORY M UNIVERSITY OF CALIFORNIA LOS ANGELES 10 MARDER, KAREN S COLUMBIA UNIVERSITY HEALTH SCIENCES OD 500 000 OD 500 000 NINDS 500 000 1S10RR028110-01 HIGH SENSITIVITY MOBILE PET FOR BRAIN IMAGING AND PROTON THERAPY MONITORING 1 EL FAKHRI,GEORGES MASSACHUSETTS GENERAL HOSPITAL NCRR 500 000 5RC1DA028790-02 MECHANISM-BASED SMALL MOLECULE EPIGENETIC MODULATORS: TARGETING SPECIFIC HDACS 5RC1AG035681-02 MUTATIONAL CLONING IN FAMILIAL DEMENTIA AND ALZHEIMERS DISEASE 2 CHEN, LIN UNIVERSITY OF SOUTHERN CALIFORNIA 2 RASKIND, WENDY H UNIVERSITY OF WASHINGTON OD 500 000 OD 500 000 2R56NS032666-11A1 TOWARD THE MOLECULAR MECHANISM OF EARLY-ONSET EPILEPSY 11 LEPPERT, MARK F UNIVERSITY OF UTAH NINDS 500 000 1S10RR027754-01 UNMC SIG SUPPORTING NEXT-GENERATION DNA SEQUENCING TECHNOLOGY 1 EUDY, JAMES UNIVERSITY OF NEBRASKA MEDICAL CENTER NCRR 500 000 5U01AG031294-03 HARNESSING GABA AND NO MIMETIC ACTIVITY FOR ALZHEIMER'S THERAPY 5R01AG013743-14 SPATIALLY ORIENTED DATABASE FOR DIGITAL BRAIN IMAGES 3 THATCHER,GREGORY R J 14 HERSKOVITS,EDWARD H UNIVERSITY OF ILLINOIS AT CHICAGO UNIVERSITY OF PENNSYLVANIA NIA 502 307 NIA 503 707 5R01AG034613-02 HIGH-RESOLUTION STRUCTURAL AND FUNCTIONAL BRAIN IMAGING OF THE MEDIAL TEMPORAL LO 2 STARK, CRAIG E UNIVERSITY OF CALIFORNIA IRVINE NIA 503 947 5R01ES017462-02 ENDOTOXIN EXPOSURE AND RISK OF PARKINSONISM 2 CHECKOWAY,HARVEY UNIVERSITY OF WASHINGTON NIEHS 504 982 5R44HD053211-03 A "LIP READING" CLICK DEVICE FOR DISABLED COMPUTER USERS 5R01NS020253-24 AGE RELATED SEIZURE SUPPRESSION 3 SCHAEFER, PHILIP R VORTANT TECHNOLOGIES, LLC 24 MOSHE, SOLOMON L ALBERT EINSTEIN COL OF MED YESHIVA UNIV NICHD 505 410 NINDS 505 592 1R01NS066340-01A1 AUTOMATED ASSESSMENT OF STRUCTURAL CHANGES &FUNCTIONAL RECOVERY POST SPINAL INJU 1 VEMURI, BABA C UNIVERSITY OF FLORIDA NINDS 506 525 5R01AG019653-09 APOLIPOPROTEIN E, ATTENTION,AND ALZHEIMER'S DISEASE 9 PARASURAMAN,RAJA GEORGE MASON UNIVERSITY NIA 506 699 5R01NS060856-02 RNAI-BASED THERAPY OF ALS 2 RANA, TARIQ M SANFORD-BURNHAM MEDICAL RESEARCH INSTIT NINDS 507 034 1R01NS070834-01 EARLY DETECTION OF CEREBRAL AMYLOID ANGIOPATHY 1 GREENBERG,STEVEN M MASSACHUSETTS GENERAL HOSPITAL NINDS 507 128 1ZIADK060101-04 TARGETED DISRUPTION THE ENZYMES OF O-GLCNAC CYCLING:ANIMAL MODELS OF DISEASE 5R01MH080240-02 AMYLOID, WHITE MATTER HYPERINTENSITIES & OUTCOMES OF LATE-LIFE DEPRESSION 4 HANOVER, JOHN A NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES 2 BUTTERS, MERYL A UNIVERSITY OF PITTSBURGH AT PITTSBURGH NIDDK 507 288 NIMH 507 714 5U01NS064049-02 LOW-FREQUENCY SINE-WAVE NEUROSTIMULATION THERAPY FOR EPILEPSY 5R01NS035129-13 HUMAN EPILEPSY GENETICS -NEURONAL MIGRATION DISORDERS 2 GOODMAN,JEFFREY H 13 WALSH,CHRISTOPHER A INSTITUTE FOR BASIC RES IN DEV DISABIL CHILDREN'S HOSPITAL BOSTON NINDS 509 416 NINDS 509 603 5R01NS014624-32 NEUROPHYSIOLOGY OF PAIN ADAPTATION AND HYPERALGESIA 32 LA MOTTE, ROBERT H YALE UNIVERSITY NINDS 509 742 5R01EY018589-03 CRYSTALLINE ANTIPROLIFERATIVE DRUGS FOR INTRAOCULAR DISEASES 3 FREEMAN, WILLIAM R UNIVERSITY OF CALIFORNIA SAN DIEGO NEI 510 230 1ZIAES102285-04 THYROID HORMONE SIGNALING 4 ARMSTRONG,DAVID NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES NIEHS 512 837 5R01AG025259-05 MULTI-ETHNIC GENOME-WIDE ALZHEIMER ASSOCIATION STUDY 5 FARRER, LINDSAY A BOSTON UNIVERSITY MEDICAL CAMPUS NIA 513 537 2R44EY018990-02 TOOLS TO OPTIMIZE PATIENT PRESENTATION SPEED AFTER ONSET OF EXUDATIVE MACULAR DEG 2 ROSER, MARK C RESULTS GROUP NEI 513 708 5R01NS055143-04 TH AND GTPCHI GENE THERAPY FOR PARKINSON'S DISEASE 4 KORDOWER,JEFFREY H RUSH UNIVERSITY MEDICAL CENTER NINDS 513 992

5R01AI068577-04 VACCINATION STRATEGIES AFTER ELIMINATION OF POLIOMYELITIS 5R01NS048425-06 HAND USE AND NEURONAL PLASTICITY AFTER DORSAL RHIZOTOMY 4 MALDONADO,YVONNE A 6 DARIAN-SMITH,CORINNA STANFORD UNIVERSITY NIAID 514 922 STANFORD UNIVERSITY NINDS 515 105 5R01DC008552-04 LANGUAGE IN PRIMARY PROGRESSIVE APHASIA 1R01AG034157-01A2 METHODOLOGY ISSUES IN A TAILORED LIGHT TREATMENT FOR PERSONS WITH DEMENTIA 4 MESULAM,MAREK-MARSEL M 1 FIGUEIRO,MARIANA NORTHWESTERN UNIVERSITY RENSSELAER POLYTECHNIC INSTITUTE NIDCD 515 547 NIA 517 629 5R01NS055371-05 DISRUPTED TRANSPORT OF NGF-TRKA SIGNALING IN MOUSE MODELS OF DOWN SYNDROME 5 MOBLEY, WILLIAM C UNIVERSITY OF CALIFORNIA SAN DIEGO NINDS 518 723 5R44AG026402-04 COMPUTERIZED EARLY DEMENTIA ASSESSMENT SYSTEM 5R01ES014049-03 NEUROLOGIC AND REPRODUCTIVE EFFECTS OF HEXANE ON WORKERS 4 O'HALLORAN,JAMES P 3 HAMMOND, S KATHARINE NEUROCOMP SYSTEMS,INC.UNIVERSITY OF CALIFORNIA BERKELEY NIA 519 014 NIEHS 519 192 5R01ES008846-10 ROLE OF ASTROCYTE INJURY IN NEUROPROTECTION 2R01EY015537-05A1 PURINES AND THE HEALTH OF RETINAL GANGLION CELLS 5R01EY012910-12 NOVEL PHOTORECEPTOR CILIA PROTEINS AND RETINAL DEGENERATIONS 10 PHILBERT, MARTIN UNIVERSITY OF MICHIGAN AT ANN ARBOR 5 MITCHELL, CLAIRE H UNIVERSITY OF PENNSYLVANIA 12 PIERCE, ERIC A UNIVERSITY OF PENNSYLVANIA NIEHS 519 206 NEI 524 425 NEI 524 862 5R01AG032132-16 CONTROL OF AMPA RECEPTOR TRAFFICKING BY BETA AMYLOID 16 MALINOW,ROBERTO UNIVERSITY OF CALIFORNIA SAN DIEGO NIA 525 158 5R44NS055421-03 WIRELESS MULTI-MODAL BRAIN MONITORING 5R01AG018917-08 A MULTIDISCIPLINARY ANALYSIS OF GELSOLIN AMYLOID DISEASE 3 LANNING, BRUCE ITN ENERGY SYSTEMS,INC.8 KELLY, JEFFERY W SCRIPPS RESEARCH INSTITUTE NINDS 526 897 NIA 526 986 5R01EY011298-13 EVALUATION OF COMPLEX INHERITANCE OF RETINAL DEGENERATION IN BARDET-BIEDL SYNDROM 13 SHEFFIELD, VAL C UNIVERSITY OF IOWA NEI 526 991 1U01AG033183-01A2 EFFICACIOUS AND SAFE ANTIBODY CATALYZED AMYLOID BETA CLEARANCE 5R01DA021779-02 GENDER EFFECTS ON AMPHETAMINE-INDUCED DOPAMINE RELEASE AND SUBJECTIVE RESPONSES 1 PAUL, SUDHIR UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON 2 MCCAUL, MARY E JOHNS HOPKINS UNIVERSITY NIA 528 773 NIDA 530 118 1ZIADA000539-04 DESCENDING MODULATION OF NERVE INJURY AND INJURY-EVOKED PAIN 4 SHIPPENBERG,TONI NATIONAL INSTITUTE ON DRUG ABUSE NIDA 530 120 1R01ES019296-01 INFLAMMATION AS A MEDIATOR OF DYNAMIC DNA MUTATIONS 1 DELANEY, SARAH BROWN UNIVERSITY NIEHS 531 295 1R01AG033613-01A1 LIPOIC ACID AND OMEGA-3 FATTY ACIDS IN ALZHEIMER'S DISEASE 3U01NS043128-09S1 NEUROPROTECTION STUDIES IN PD: A COORDINATING CENTER 5R01HD036071-12 GENOTYPE-PHENOTYPE RELATIONSHIPS IN FRAGILE X FAMILIES 1R01AG036755-01A1 A LARGE RANDOMIZED TRIAL OF VITAMIN D, OMEGA-3 FATTY ACIDS AND COGNITIVE DECLINE 1 SHINTO, LYNNE H OREGON HEALTH AND SCIENCE UNIVERSITY 9 KIEBURTZ, KARL D UNIVERSITY OF ROCHESTER 12 HAGERMAN, RANDI J UNIVERSITY OF CALIFORNIA DAVIS 1 KANG, JAE H BRIGHAM AND WOMEN'S HOSPITAL NIA 532 428 NINDS 533 001 NICHD 535 019 NIA 535 208 2R44DC008477-02 SUSTAINED RELEASE INNER EAR DELIVERY OF CORTICOSTEROID 2 SLATTERY, WILLIAM H O-RAY PHARMA, INC. NIDCD 535 685 5R01NS055916-03 ATTENTION AND EXECUTIVE FUNCTIONING IN AGING AND PARKISONISM 5R01GM056888-13 RAD50: DNA DAMAGE & THE SUPPRESSION OF MALIGNANCY 3 SCHNEIDER, JAY S THOMAS JEFFERSON UNIVERSITY 13 PETRINI, JOHN HJ SLOAN-KETTERING INSTITUTE FOR CANCER RES NINDS 536 204 NIGMS 537 902 5R01MH078821-17 MOLECULAR GENETIC APPROACHES TO LEARNING AND MEMORY 17 TONEGAWA,SUSUMU MASSACHUSETTS INSTITUTE OF TECHNOLOGY NIMH 538 354 1ZIANS003106-02 ROLES OF CDK5 IN NEURODEVELOPMENT AND NEURODEGENERATION 2 GINIGER, EDWARD NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE NINDS 538 425 5R01NS012674-32 EXPERIMENTAL CREUTZFELDT JACOB DISEASE 32 MANUELIDIS,LAURA YALE UNIVERSITY NINDS 539 613 1R01NS069605-01 A GENOMIC APPROACH TO EPILEPSY 1 MEFFORD,HEATHER C UNIVERSITY OF WASHINGTON NINDS 540 000 2R01NS037466-11 SEARCH FOR GENES INFLUENCING CHILDHOOD ABSENCE EPILEPSY 11 DURNER, MARTINA MOUNT SINAI SCHOOL OF MEDICINE NINDS 540 180

5R01AG005213-21 EFFECTS OF AGE ON THE COGNITIVE ERPD/CARDIAC WAVE EFFECT 1R01AG035361-01A1 NOVEL GABA-A MODULATORS AS COGNITIVE ENHANCERS 5R01EY014005-08 AGE-INDUCED PHENOTYPE OF THE RETINAL PIGMENT EPITHELIUM 21 FRIEDMAN, DAVID COLUMBIA UNIVERSITY HEALTH SCIENCES 1 ROWLETT, JAMES K HARVARD UNIVERSITY(MEDICAL SCHOOL)8 HANDA, JAMES T JOHNS HOPKINS UNIVERSITY NIA 540 318 NIA 542 446 NEI 545 274 1R01AG035379-01A1 APOE EFFECTS ON NEURON SIGNALING AND FUNCTION VIA APOER2 1 REBECK, G.WILLIAM GEORGETOWN UNIVERSITY NIA 545 296 1R01ES019188-01 POPULATION-BASED STUDY OF ENVIRONMENTAL RISK FACTORS FOR ALS 1 WEISSKOPF, MARC G HARVARD UNIVERSITY(SCH OF PUBLIC HLTH)NIEHS 545 438 5R01NS058529-02 NONRECURRENT REARRANGEMENTS, GENOME ARCHITECTURE AND NEURODEGENERATIVE DISEASE.2 LUPSKI, JAMES RICHARD BAYLOR COLLEGE OF MEDICINE NINDS 547 274 5R01AG034556-02 NEURAL PROCESSES UNDERLYING COGNITIVE AGING 2 BUCKNER, RANDY L MASSACHUSETTS GENERAL HOSPITAL NIA 547 348 5R01EY019126-03 ADMIXTURE MAPPING OF GLAUCOMA GENES IN AFRICAN AMERICANS 3 HAUSER, MICHAEL A DUKE UNIVERSITY NEI 548 440 1R01AG033581-01A2 CONVERSATIONAL ENGAGEMENT AS A MEANS TO DELAY ALZHEIMER'S DISEASE ONSET 1 DODGE, HIROKO HAYAMA OREGON HEALTH AND SCIENCE UNIVERSITY NIA 548 846 2R01NS055251-05 N-TYPE CALCIUM CHANNELS IN NOCICEPTIVE NEURONS 5 LIPSCOMBE, DIANE BROWN UNIVERSITY NINDS 549 609 1R01MH092673-01 GFAP AS A NOVEL HIV/NEUROAIDS BIOMARKER 2R01NS038194-11 SIGNALING MECHANISMS IN NEURONAL DEGENERATION 5R01NS062069-02 PATHOBIOLOGY OF RETINAL VASCULOPATHY WITH CEREBAL LEUKODYSTROPHY (RVCL)1 HE, JOHNNY J INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS 11 ARONIN, NEIL UNIV OF MASSACHUSETTS MED SCH WORCESTER 2 JEN, JOANNA C UNIVERSITY OF CALIFORNIA LOS ANGELES NIMH 549 636 NINDS 550 885 NINDS 552 119 5R01AG026096-05 CIND: RISK FACTORS FOR CONVERSION TO DEMENTIA 1R01AG033673-01A1 AEROBIC FITNESS IN SLOWING THE PROGRESSION OF ALZHEIMER'S DISEASE 5 UNVERZAGT,FREDERICK W.1 BURNS, JEFFREY MURRAY INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS UNIVERSITY OF KANSAS MEDICAL CENTER NIA 552 490 NIA 553 397 2R01AG021927-06A1 FUNCTIONAL CHANGE IN MILD COGNITIVE IMPAIRMENT 6 MARSON, DANIEL C UNIVERSITY OF ALABAMA AT BIRMINGHAM NIA 554 173 5R01HD054569-04 QUALITY OF LIFE FOR SCI CLINICAL TRIALS: DEVELOPMENT OF THE SCI-QOL 4 TULSKY, DAVID SCOTT KESSLER FOUNDATION,INC.NICHD 554 430 5R01NS057560-02 NONINVASIVE STUDY OF CEREBRAL ATP METABOLISM,BIOENERGETICS AND BRAIN FUNCTION 4R37AG010880-18 GLUCOSE REGULATION AND MEMORY IN ALZHEIMER'S DISEASE 5P30AT005895-02 CORE CENTER FOR MULTIMODAL EVAULATION OF ACUPUNCTURE MECHANISMS 5R01AG029672-04 IMPROVING COGNITIVE OUTCOME PRECISION & RESPONSIVENESS WITH MODERN PSYCHOMETRICS 2 CHEN, WEI UNIVERSITY OF MINNESOTA TWIN CITIES 18 CRAFT, SUZANNE UNIVERSITY OF WASHINGTON 2 ROSEN, BRUCE R MASSACHUSETTS GENERAL HOSPITAL 4 CRANE, PAUL K UNIVERSITY OF WASHINGTON NINDS 554 946 NIA 556 491 NCCAM 556 805 NIA 557 232 1ZIADK060109-04 MEMBRANE TRAFFICKING AND DYSFUNCTION IN GLYCOLIPID STORAGE DISEASES 5R01NS039958-10 NEUROPROTECTION BY MITOCHONDRIA-TARGETED ANTIOXIDANTS 4 BLANCHETTE-MACK IE, E. JOAN 10 KALYANARAMAN,BALARAMAN NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES MEDICAL COLLEGE OF WISCONSIN NIDDK 557 321 NINDS 557 341 5R01AG033193-02 COLLABORATIVE GWAS OF DEMENTIA, AD AND RELATED MRI AND COGNITIVE ENDOPHENOTYPES 2 SESHADRI, SUDHA BOSTON UNIVERSITY MEDICAL CAMPUS NIA 558 610 5U44NS057966-05 AUTOMATED SEIZURE DETECTION FOLLOWING NERVE AGENT EXPOSURE 5 SHERMAN, DAVID LEE INFINITE BIOMEDICAL TECHNOLOGIES, LLC OD 558 738 5R01HD065160-02 PREDICTING COGNITIVE DECLINE IN ADULTS WITH DOWN SYNDROME 2 LOTT, IRA T UNIVERSITY OF CALIFORNIA IRVINE NICHD 558 918 5R01EY015435-06 ROLE OF RPE-DERIVED VEGF IN CHOROID DEVELOPMENT AND STABILITY 6 D'AMORE, PATRICIA ANN SCHEPENS EYE RESEARCH INSTITUTE NEI 559 600

1ZIANS002976-12 SPASTICITY AND SPINAL MECHANISMS OF HUMAN MOTOR CONTROL 5R01HL088615-03 MECHANISMS OF ARRHYTHMIA SUSCEPTIBILITY IN SPINAL CORD INJURED RATS 5R01AR036820-25 COLLAGEN GENE STRUCTURE AND EXPRESSION 1R01MH092225-01 CLINICAL TRIAL OF CNS PENETRATING ART TO PREVENT NEUROAIDS IN CHINA 5R01AI049724-10 ECOLOGY OF ENCEPHALITIS VIRUSES IN THE USA 12 FLOETER, MARY KAY 3 DICARLO,STEPHEN E 25 OLSEN, BJORN REINO 1 LETENDRE,SCOTT L 10 UNNASCH,THOMAS R NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE WAYNE STATE UNIVERSITY HARVARD UNIVERSITY(MEDICAL SCHOOL)UNIVERSITY OF CALIFORNIA SAN DIEGO UNIVERSITY OF SOUTH FLORIDA NINDS 560 689 NHLBI 563 272 NIAMS 563 918 NIMH 566 532 NIAID 566 592 5R01NS031348-18 GENETIC DETERMINANTS OF EPILEPSY IN MURINE SYSTEMS 18 FRANKEL, WAYNE N JACKSON LABORATORY NINDS 566 950 5R01MH078748-04 NEUROAIDS IN INDIA 4 MARCOTTE,THOMAS D UNIVERSITY OF CALIFORNIA SAN DIEGO NIMH 568 839 5R01EY018335-04 RDS MUTATIONS: GENE THERAPY FOR ADRP, MACULAR DEGENERATION AND PATTERN DYSTROPHY 4 LEWIN, ALFRED S UNIVERSITY OF FLORIDA NEI 571 186 5R01EY009620-19 EXPRESSION AND FUNCTION OF CONE PIGMENT GENES 19 NEITZ, JAY UNIVERSITY OF WASHINGTON NEI 571 470 1ZIAAG000957-08 ASSESSMENT OF CANDIDATE LOCI IN NEUROLOGICAL DISEASES 5R01AG019604-08 EXPLAINING DISPARITIES IN COGNITIVE FUNCTION IN SENIORS 8 SINGLETON,ANDREW 8 SCHWARTZ,BRIAN S NATIONAL INSTITUTE ON AGING JOHNS HOPKINS UNIVERSITY NIA 573 485 NIA 575 248 1ZIAMH002914-03 TREATMENT OF MEDICAL CONDITIONS AMONG INDIVIDUALS WITH AUTISM SPECTRUM DISORDERS 3 SWEDO, SUSAN NATIONAL INSTITUTE OF MENTAL HEALTH NIMH 578 006 2R44DA026220-02A1 OPERANT BEHAVIORAL INSTRUMENT FOR MEASURING TRIGEMINAL NEUROPATHIC PAIN IN RODENT 2 MILLS, RICHARD H STOELTING COMPANY NIDA 578 871 1ZIABC011214-02 POST-TRANSCRIPTIONAL REGULATION OF INTERLEUKIN-7 RECEPTOR EXPRESSION 5R44AG032784-03 DEVELOPMENT OF E64D FOR ALZHEIMER'S DISEASE 1ZIAAG000313-10 APOPTOSIS IN NEURODEGENERATIVE DISORDERS 2 PARK, JUNG-HYUN DIVISION OF BASIC SCIENCES - NCI 3 HOOK, GREGORY R AMERICAN LIFE SCIENCE PHARMACEUTICALS 10 MATTSON, MARK NATIONAL INSTITUTE ON AGING NCI 579 177 NIA 581 324 NIA 582 406 5R01HL087827-04 AN ANIMAL MODEL OF DIABETIC AUTONOMIC NEUROPATHY:STUDY OF MECHANISM AND THERAPY 4 GALPER, JONAS BERNARD TUFTS MEDICAL CENTER NHLBI 583 678 5R01NS060722-02 STRUCTURAL MRI MARKER(S) OF PARKINSON'S DISEASE'S PROGRESSION 1ZIAHG200335-05 THE INFLUENCE OF FAMILIAL SOCIAL CONTEXT ON RISK DISSEMINATION AND COPING 2 HUANG, XUEMEI PENNSYLVANIA STATE UNIV HERSHEY MED CTR 5 KOEHLY, LAURA NATIONAL HUMAN GENOME RESEARCH INSTITUTE NINDS 584 352 NHGRI 584 894 1ZIANS003055-03 COMPREHENSIVE MULTIMODAL ANALYSIS OF PATIENTS WITH NEUROIMMUNOLOGICAL DISEASES 5R01MH083579-03 DISSECTING THE ROLE OF HIV-1 TAT AND THE CHEMOKINE AXIS IN SUBTYPE-SPECIFICITY OF 3 BIELEKOVA,BIBIANA 3 PRASAD,VINAYAKA R NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE ALBERT EINSTEIN COL OF MED YESHIVA UNIV NINDS 585 550 NIMH 587 768 5R01EY012543-11 CRX AND ITS REGULATORY NETWORK IN RETINAL DEGENERATIONS 11 CHEN, SHIMING WASHINGTON UNIVERSITY NEI 588 158 5R01HD057564-03 PERINATAL CHOLINE THERAPY IN A MOUSE MODEL OF DOWN SYNDROME & ALZHEIMER'S DISEASE 3 STRUPP,BARBARA J CORNELL UNIVERSITY ITHACA NICHD 588 346 3P30NS045776-07S1 INTERDEPARTMENTAL NEUROSCIENCE CENTER 1ZIADK060100-15 STRUCTURE AND FUNCTION OF DYNAMIN, A 100KD GTPASE INVOLVED IN ENDOCYTOSIS 7 BHIDE, PRADEEP G MASSACHUSETTS GENERAL HOSPITAL 15 HINSHAW, JENNY E NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES NINDS 590 000 NIDDK 590 949 9R42GM093388-02A2 MITOCHONDRIAL DYSFUNCTION IN HAART: POINT OF CARE TESTS 2 MARUSICH,MICHAEL F MITOSCIENCES, INC NIGMS 591 470 2R01NS036326-12A2 MECHANISM OF FAMILIAL DYSAUTONOMIA 12 SLAUGENHAUPT,SUSAN A MASSACHUSETTS GENERAL HOSPITAL NINDS 591 844

1R01AG034946-01A1 ALZHEIMER'S DISEASE MULTIPLE INTERVENTION TRIAL - ADMIT 1 CALLAHAN,CHRISTOPHER M INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS NIA 592 129 5R01AG028076-02 CEREBROMICROVASCULAR DISEASE IN ELDERLY WITH DIABETES 2 NOVAK, VERA BETH ISRAEL DEACONESS MEDICAL CENTER NIA 592 598 5R37MH049428-18 GENETIC REGULATION OF TELENCEPHALON DEVELOPMENT 18 RUBENSTEIN,JOHN L. R UNIVERSITY OF CALIFORNIA SAN FRANCISCO NIMH 592 684 5R01EY004542-28 DEVELOPMENT AND MAINTENANCE OF LENS TRANSPARENCY 28 CLARK, JOHN IRWIN UNIVERSITY OF WASHINGTON NEI 592 720 1R01HL096750-01A1 RECOVERY OF RESPIRATORY FUNCTION AFTER SPINAL CORD INJURY 1 SIECK, GARY C MAYO CLINIC NHLBI 592 820 5R01MH054846-14 GERIATRIC DEPRESSION: RISK FACTORS FOR ADVERSE OUTCOMES 14 STEFFENS,DAVID C DUKE UNIVERSITY NIMH 595 553 2R01AG021028-06A2 HETEROGENEITY OF MILD COGNITIVE IMPAIRMENT (MCI)6 DECARLI, CHARLES UNIVERSITY OF CALIFORNIA DAVIS NIA 595 777 2R01EB006136-05 COMPUTER-ASSISTED FUNCTIONAL NEUROSURGERY 5 DAWANT,BENOIT M VANDERBILT UNIVERSITY NIBIB 596 568 5R01EY002120-32 PATHOGENESIS OF GLAUCOMATOUS OPTIC NERVE DAMAGE 32 QUIGLEY, HARRY ALAN JOHNS HOPKINS UNIVERSITY NEI 596 589 1R01ES019319-01 MECHANISMS OF ENVIRONMENTAL AND NUCLEAR AND MITOCHONDRIAL MUTAGENESIS 1 BIELAS, JASON H. FRED HUTCHINSON CANCER RESEARCH CENTER NIEHS 597 220 5R01EY011996-11 RETINAL DISEASE: MOLECULAR BASIS AND PATHOPHYSIOLOGY 9R44GM093642-02 NOVEL SYSTEMS FOR MAMMALIAN EXPRESSION, INTEGRATION, AND KNOCKOUT OF PREVIOUSLY "11 NISHINA, PATSY M JACKSON LABORATORY NEI 599 943 2 GODISKA, RONALD LUCIGEN CORPORATION NIGMS 600 001 2R01GM039561-22 PHYSIOLOGICAL FUNCTIONS OF G-ALPHA-I/O AND CONTROL BY REGULATORS OF G PROTEIN SIG 22 NEUBIG, RICHARD R UNIVERSITY OF MICHIGAN AT ANN ARBOR NIGMS 600 839 5R01EY017362-04 GENETIC EPIDEMIOLOGY OF AGE-RELATED MACULAR DEGENERATION 3U01AG016976-12S1 NATIONAL ALZHEIMER'S COORDINATING CENTER (NACC)4 SCHAUMBERG,DEBRA A 12 KUKULL, WALTER ANTHONY BRIGHAM AND WOMEN'S HOSPITAL UNIVERSITY OF WASHINGTON NEI 601 411 NINDS 602 368 5R01EY007065-24 CELLULAR BIOLOGY OF THE TRABECULAR MESHWORK 24 FAUTSCH,MICHAEL P MAYO CLINIC NEI 602 693 5R01NS050537-07 ROLE OF FIBRIN IN ALZHEIMER'S DISEASE 7 STRICKLAND,SIDNEY ROCKEFELLER UNIVERSITY NINDS 603 457 2R01AG022374-06A2 BIOMARKERS IN EARLY ALZHEIMER'S DISEASE (AD).5R01NS045734-07 VASCULAR RESPONSES AS THERAPEUTIC TARGETS AFTER SCI 6 DE LEON, MONY J NEW YORK UNIVERSITY SCHOOL OF MEDICINE 7 HAGG, THEO UNIVERSITY OF LOUISVILLE NIA 604 652 NINDS 605 517 5R01EB003151-33 SOLID STATE NMR STUDIES OF PEPTIDES AND PROTEINS 5R01NS064040-02 NEURAL SUBSTRATES OF SWITCHING IN PARKINSON'S DISEASE 5R01EY005951-24 OXIDATIVE DAMAGE AND CONE CELL DEATH IN RP 33 GRIFFIN, ROBERT GUY 2 DISBROW,ELIZABETH A 24 CAMPOCHIARO,PETER A MASSACHUSETTS INSTITUTE OF TECHNOLOGY UNIVERSITY OF CALIFORNIA DAVIS JOHNS HOPKINS UNIVERSITY NIBIB 607 508 NINDS 608 390 NEI 610 627 5R01NS061965-03 DTI AS A TOOL TO IDENTIFY INFANTS WITH KRABBE DISEASE IN NEED OF URGENT TREATMENT 3 ESCOLAR, MARIA L UNIVERSITY OF NORTH CAROLINA CHAPEL HILL NINDS 611 067 5R01AG030114-02 THERAPEUTIC EFFECTS OF CATARACT REMOVAL IN ALZHEIMER'S DISEASE 2 GILMORE, GROVER CLEVELAND CASE WESTERN RESERVE UNIVERSITY NIA 612 414 5R01NS047130-03 TAI CHI AND PARKINSON'S DISEASE 3 LI, FUZHONG OREGON RESEARCH INSTITUTE NINDS 614 131 5R42AG023443-05 ANTI-AGING MITOCHONDRIAL PROTEIN THERAPY FOR ALZHEIMER’S DISEASE AND SARCOPENIA 5 BENNETT, JAMES PEPPER GENCIA CORPORATION NIA 614 734 5R01DC001150-19 EFFICACY OF VOICE TREATMENT FOR PARKINSON'S DISEASE 19 RAMIG, LORRAINE O UNIVERSITY OF COLORADO AT BOULDER NIDCD 616 814 1R01EY021024-01A2 EPIGENETIC AGING OF THE OXIDATIVE STRESS RESPONSE IN THE MOUSE RPE 5R01NS040554-09 QUANTITATIVE GENETIC STUDY OF SEIZURES 1 HJELMELAND,LEONARD MARTIN 9 FERRARO,THOMAS N UNIVERSITY OF CALIFORNIA DAVIS UNIVERSITY OF PENNSYLVANIA NEI 617 539 NINDS 618 478

5U01MH076179-05 CONTROLLED TRIAL OF DBS FOR OCD 1ZIABC010761-05 STUDIES OF PROTEINS WITH IMPORTANT ROLES IN IMMUNOLOGY ANDOR CANCER BIOLOGY 2R01EY001919-33 CELLULAR MECHANISMS OF INHERITED RETINAL DEGENERATION 5 GREENBERG,BENJAMIN D 5 LUBKOWSKI,JACEK T 33 LAVAIL,MATTHEW M BUTLER HOSPITAL(PROVIDENCE, RI)DIVISION OF BASIC SCIENCES - NCI UNIVERSITY OF CALIFORNIA SAN FRANCISCO NIMH 618 588 NCI 619 065 NEI 619 976 5R01NS018741-26 NEURAL BASIS OF ENDOGENOUS POTENTIALS IN HUMANS 26 HALGREN, ERIC UNIVERSITY OF CALIFORNIA SAN DIEGO NINDS 622 600 5R01AG030155-04 THE COST OF DEMENTIA 4 HURD, MICHAEL D RAND CORPORATION NIA 622 814 5R01MH064109-08 BEHAVIORAL ROLE OF HYPOCRETIN 8 SIEGEL, JEROME M UNIVERSITY OF CALIFORNIA LOS ANGELES NIMH 622 861 5U01MH083507-03 TEXAS REPOSITORY FOR AIDS NEUROPATHOGENESIS RESEARCH 3 GELMAN,BENJAMIN B UNIVERSITY OF TEXAS MEDICAL BR GALVESTON NIMH 622 947 5R01GM090311-02 NOVEL MITOCHONDRIALLY ENCODED PEPTIDES AND THEIR ROLE IN HEALTH AND DISEASE 2 COHEN, PINCHAS UNIVERSITY OF CALIFORNIA LOS ANGELES OD 626 685 2R01EY007716-19A2 APPLICATION OF PSYCHOPHYSICAL MODELS TO VISUAL DISORDERS 19 SWANSON, WILLIAM HOWARD INDIANA UNIVERSITY BLOOMINGTON NEI 626 865 5R01EY008247-21 BIOLOGY OF TRABECULAR RESPONSE TO LASER TRABECULOPLASTY 21 ACOTT, TED S OREGON HEALTH AND SCIENCE UNIVERSITY NEI 627 661 5R01EY018405-04 EXPANDING QUALITY CARE FOR GLAUCOMA THROUGH A PROVIDER-PATIENT PARTNERSHIP 4 LEE, PAUL P DUKE UNIVERSITY NEI 627 720 5R01AG034087-02 INFLAMMATION, LONG-TERM DIABETES CHARACTERISTICS,AND COGNITIVE DECLINE 2 SCHNAIDER BEERI,MICHAL MOUNT SINAI SCHOOL OF MEDICINE NIA 628 130 5U01AI078205-02 MUCOSAL VECTOR WITH TLR3 AGONIST FOR PROTECTION AGAINST VEE 2 TUCKER, SEAN N VAXART, INC. NIAID 631 471 5R01NR009543-04 CLINICAL TRIAL TO ENHANCE CAREGIVER PHYSICAL ACTIVITY 5R01EY015224-08 COMPLEMENT ACTIVATION IN GLAUCOMA 4 FARRAN, CAROL J RUSH UNIVERSITY MEDICAL CENTER 8 DANIAS, JOHN SUNY DOWNSTATE MEDICAL CENTER NINR 633 466 NEI 634 045 5R44EY018778-03 ANTI-HTRA1 THERAPY FOR AMD 3 MUELLER, ALAN L NAVIGEN, INC. NEI 634 302 5U01AG029213-03 ALZHELMER'S DISEASE DRUG DEVELOPMENT PROGRAM 3 SMITH, AMOS B UNIVERSITY OF PENNSYLVANIA NIA 634 310 5R01AG016324-07 BRAIN IMAGING & COGNITION IN SUBJECTS AT RISK FOR ALZHEIMER'S DISEASE 2R01HD037283-11A2 HUMAN NEUROBEHAVIORAL PHENOTYPES ASSOCIATES WITH THE EXTENDED PWS/AS DOMAIN 7 BASSETT, SUSAN SPEAR 11 BEAUDET,ARTHUR L JOHNS HOPKINS UNIVERSITY BAYLOR COLLEGE OF MEDICINE NIA 634 682 NICHD 634 739 5R01EY019473-02 NOVEL CLINICAL AND OCULAR IMAGING OUTCOMES WITH LONG-TERM FOLLOW-UP IN MS 2 BALCER, LAURA UNIVERSITY OF PENNSYLVANIA NEI 636 704 1S10RR029663-01 A MULTIPHOTON MICROSCOPE FOR TRANSLATIONAL AND BASIC BIOMEDICAL RESEARCH 5R01NS062384-02 AGE OF ONSET AND HUNTINGTONS DISEASE 1 MAXFIELD,FREDERICK R 2 MCMURRAY,CYNTHIA THERESE WEILL MEDICAL COLLEGE OF CORNELL UNIV UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB NCRR 638 318 NINDS 642 465 5R01AG028144-04 PATHWAYS FROM STRESS TO METABOLIC SYNDROME AND HEALTH DECLINE IN AGED CAREGIVERS 4 FREDMAN, LISA BOSTON UNIVERSITY MEDICAL CAMPUS NIA 644 239 1ZICEY000478-02 NATIONAL OPHTHALMIC DISEASE GENOTYPING AND PHENOTYPING NETWORK - EYEGENE 2 TUMMINIA, SANTA NATIONAL EYE INSTITUTE NEI 644 910 5R01EY008208-20 DIAGNOSTIC INNOVATIONS IN GLAUCOMA STUDY: VISUAL FUNCTION 20 MEDEIROS, FELIPE UNIVERSITY OF CALIFORNIA SAN DIEGO NEI 645 518 1ZIANS003037-04 STUDIES OF HEREDITARY NEUROLOGICAL DISEASE:CLINICAL TRIALS 4 FISCHBECK,KENNETH NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE NINDS 649 000 1U01HL096814-01 ARIC NEUROCOGNITIVE STUDY(ARIC-NCS)1 HEISS, GERARDO UNIVERSITY OF NORTH CAROLINA CHAPEL HILL NHLBI 650 072 5R01NS067128-02 EFFECTS OF PARKINSON'S DISEASE ON PERCEPTION,COGNITION, AND GAIT 2 CRONIN-GOLOMB,ALICE M.BOSTON UNIVERSITY NINDS 651 032 1R01NS071463-01 ENVIRONMENTAL AND GENETIC RISK FACTORS FOR PEDIATRIC MS 1 WAUBANT,EMMANUELLE LAURENCE UNIVERSITY OF CALIFORNIA SAN FRANCISCO NINDS 653 354

5R01EB007163-05 WEARABLE-SENSOR SYSTEM FOR MONITORING MOTOR FUNCTION 5 DE LUCA, CARLO J BOSTON UNIVERSITY NIBIB 654 993 5R01GM042699-21 BIOCHEMISTRY OF PRE-MRNA SPLICING 21 KRAINER, ADRIAN R COLD SPRING HARBOR LABORATORY NIGMS 656 937 2R01EY013435-09 GENETIC SUSCEPTIBILITY TO AGE-RELATED MACULAR DEGENERATION 9 ALLIKMETS,RANDO L COLUMBIA UNIVERSITY HEALTH SCIENCES NEI 656 943 5R01HL045636-18 CEREBRAL FUNCTION AFTER HYPOTHERMIC CIRCULATORY ARREST 5R01AG034570-02 NEURAL AND BIOCHEMICAL MECHANISMS OF COGNITIVE AGING 18 GRIEPP, RANDALL MOUNT SINAI SCHOOL OF MEDICINE 2 JAGUST, WILLIAM J. UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB NHLBI 657 250 NIA 659 774 5R01EB002095-08 AUTOMATED MR IMAGE ANALYSIS IN MS: IDENTIFICATION OF A SURROGATE 8 NARAYANA,PONNADA A UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON NIBIB 664 344 5R01EY011309-14 ETIOLOGIC STUDIES OF AGE-RELATED MACULAR DEGENERATION 14 SEDDON, JOHANNA M TUFTS MEDICAL CENTER NEI 668 428 1R01AR059270-01 ADIPOSITY AND BONE LOSS IN SPINAL CORD INJURY 1 MORSE, LESLIE R SPAULDING REHABILITATION HOSPITAL NIAMS 669 423 5R01DC009977-02 SENSELAB: INTEGRATION OF MULTIDISCIPLINARY SENSORY DATA 2 SHEPHERD,GORDON MURRAY YALE UNIVERSITY NIDCD 669 843 1R01NS066929-01A1 PILOT TRIAL OF BUMETANIDE FOR NEONATAL SEIZURES 5RC2AG036419-02 BRIDGING COGNITIVE AGING IN RODENTS TO MAN USING FMRI IN AMNESTIC MCI 1 SOUL, JANET SUSAN 2 GALLAGHER,MICHELA CHILDREN'S HOSPITAL BOSTON JOHNS HOPKINS UNIVERSITY NINDS 675 178 NIA 676 643 1ZIAAI000746-13 HETEROTRIMERIC G PROTEIN SIGNALING IN ALLERGIC INFLAMMATION 13 DRUEY, KIRK M NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES NIAID 678 558 5U01NS058158-05 PROSTANOID MODULATORS THAT REDUCE BRAIN INJURY AND INFLAMMATION AFTER SEIZURES 5 DINGLEDINE,RAYMOND J EMORY UNIVERSITY OD 681 405 5R01NS029029-18 QUANTITATIVE MR IMAGING AND PROTON SPECTROSCOPY IN MS 18 GROSSMAN,ROBERT I.NEW YORK UNIVERSITY SCHOOL OF MEDICINE NINDS 681 966 1R01AG033288-01A1 ESTROGEN RECEPTOR-BETA PHYTOSERMS FOR MANAGEMENT OF MENOPAUSE AND AGE-ASSOCIATED 1 SCHNEIDER, LON S UNIVERSITY OF SOUTHERN CALIFORNIA NIA 686 664 5R01EY011610-14 IOP-RELATED FORCE AND FAILURE IN THE OPTIC NERVE HEAD 14 BURGOYNE,CLAUDE F EMANUEL HOSPITAL AND HEALTH CENTER NEI 687 399 1U01NS073476-01 ACCELERATING DRUG AND DEVICE EVALUATION THROUGH INNOVATIVE CLINICAL TRIAL DESIGN 1ZIABC010440-09 PROTEIN STRUCTURE, STABILITY,AND AMYLOID FORMATION 1 BARSAN, WILLIAM G UNIVERSITY OF MICHIGAN AT ANN ARBOR 9 NUSSINOV, RUTH DIVISION OF BASIC SCIENCES - NCI OD 688 948 NCI 689 125 5R01NS041509-09 MECHANISMS OF DEEP BRAIN STIMULATION 9 PERLMUTTER, JOEL SYNES WASHINGTON UNIVERSITY NINDS 691 229 1R01AG037497-01 CHARACTERIZING THE EVOLUTION OF AMYLOID DEPOSITION IN NORMAL ELDERLY 1 JOHNSON, KEITH A. MASSACHUSETTS GENERAL HOSPITAL NIA 694 513 5R01AG033032-02 APATHY IN ALZHEIMER'S DISEASE METHYLPHENIDATE TRIAL 1R01HD064850-01 COOPERATIVE LEAD DEVELOPMENT PROGRAM FOR TREATMENT OF SPINAL MUSCULAR ATROPHY 2 MINTZER,JACOBO E 1 ANDROPHY,ELLIOT J MEDICAL UNIVERSITY OF SOUTH CAROLINA INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS NIA 709 569 NICHD 710 591 5R01NS063897-02 VIRAL EVOLUTION IN PEROPHERAL MACROPHAGES AND BRAIN DURING PROGRESSION TO AIDS 2 SALEMI, MARCO UNIVERSITY OF FLORIDA NINDS 711 142 7R01EY014458-07 SIBLING STUDY OF AGE-RELATED MACULAR DEGENERATION 7 DEANGELIS,MARGARET M UNIVERSITY OF UTAH NEI 711 564 1ZIAAG000966-03 NEUROIMAGING, BEHAVIORAL NEUROLOGY AND DEVELOPMENT OF 3T MRI PROJECTS 1ZIAAA000083-17 THE ROLE OF DNA DAMAGE IN HUMAN DISEASE:NEURODEGENERATION AND CANCER 1R01MH086881-01A1 GERIATRIC DEPRESSION: PET STUDIES OF PATHOPHYSIOLOGY AND TREATMENT RESPONSE 3 EGAN, JOSEPHINE NATIONAL INSTITUTE ON AGING 17 BROOKS, PHILIP J NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM 1 SMITH, GWENN S JOHNS HOPKINS UNIVERSITY NIA 711 883 NIAAA 714 119 NIMH 716 137

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5R01EY014743-08 OPHTHALMIC IMAGING USING ADAPTIVE OPTICS AND OCT 5R01AG012975-13 EPIDEMIOLOGY OF FUNCTIONAL STATUS IN ELDERLY HISPANICS 5U10EY006594-23 EPIDEMIOLOGY OF AGE-RELATED MACULAR DEGENERATION AND OTHER RETINAL DISEASES 8 WERNER, JOHN S UNIVERSITY OF CALIFORNIA DAVIS 13 HAAN, MARY N. UNIVERSITY OF CALIFORNIA SAN FRANCISCO 23 KLEIN, RONALD UNIVERSITY OF WISCONSIN MADISON NEI 1 060 235 NIA 1 072 817 NEI 1 082 979 2R44CA112852-03 ULTRASOUND ABLATION ON BONE CANCER UNDER CT FLUOROSCOPY 2R01NS049477-06A1 A HAPLOTYPE MAP FOR MULTIPLE SCLEROSIS 1ZIAAI000637-19 DEVELOPMENT OF NEW APPROACHES TO VACCINES AGAINST TBEV AND WEST NILE VIRUS 3 BURDETTE,EVERETTE C 6 HAUSER, STEPHEN L 19 PLETNEV,ALEXANDER ACOUSTIC MEDSYSTEMS,INC.UNIVERSITY OF CALIFORNIA SAN FRANCISCO NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES NCI 1 083 824 NINDS 1 089 455 NIAID 1 098 362 1ZIAES080048-20 CELLULAR MECHANISMS OF XENOBIOTIC TRANSPORT 1ZIADK059701-37 REACTIONS AND IMMUNOCHEMISTRY OF CARBOHYDRATES 4U01NS050095-06 PARKINSON'S DISEASE DATA ORGANIZING CENTER 20 MILLER, DAVID NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES 37 KOVAC, PAVOL NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES 6 KURLAN, ROGER M UNIVERSITY OF ROCHESTER NIEHS 1 120 467 NIDDK 1 125 125 NINDS 1 137 270 5R01EB000473-09 BIOIMAGING AND INTERVENTION IN LOCALIZATION-RELATED EPILEPSY 9 DUNCAN, JAMES S YALE UNIVERSITY NIBIB 1 140 105 7R01ES010751-10 MOLECULAR EPIDEMIOLOGY OF PARKINSON'S DISEASE 10 MARAGANORE,DEMETRIUS MICHAEL NORTHSHORE UNIV HEALTHSYSTEM RES INST NIEHS 1 146 714 1ZIABC010822-04 MOLECULAR DETERMINANTS OF CHROMOSOME TRANSMISSION AND CELL CYCLE REGULATION 1U24NS063930-01A1 THE INTERNATIONAL EPILEPSY ELECTROPHYSIOLOGY DATABASE 4 BASRAI, MUNIRA DIVISION OF BASIC SCIENCES - NCI 1 LITT, BRIAN UNIVERSITY OF PENNSYLVANIA NCI 1 148 445 NINDS 1 152 456 1ZIANS002139-36 PHARMACOLOGY AND PHYSIOLOGY OF THE SUBSTANTIA NIGRA AND BASAL GANGLIA 36 WALTERS, JUDITH RICHMOND NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE NINDS 1 153 296 1ZIAEY000272-20 INHERITED OCULAR DISEASES 20 HEJTMANCIK,JAMES F NATIONAL EYE INSTITUTE NEI 1 170 614 5R01AG027435-05 EVOLUTION OF MEMORY-RELATED FMRI ACTIVATION OVER THE COURSE OF MCI AND AD 1ZIAAR041156-04 ROLE OF MAST CELLS IN IMMUNITY AND AUTOIMMUNITY 5 SPERLING, REISA A. BRIGHAM AND WOMEN'S HOSPITAL 4 RIVERA, JUAN NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES NIA 1 170 742 NIAMS 1 174 336 5R01NS032830-16 GENETIC EPIDEMIOLOGY OF MULTIPLE SCLEROSIS 16 HAINES,JONATHAN L VANDERBILT UNIVERSITY NINDS 1 177 223 5R01AG027944-03 GENOMIC CONVERGENCE IN ALZHEIMER DISEASE 5R01EY016093-04 MID-LEVEL VISION SYSTEMS FOR LOW VISION 3 PERICAK-VANCE,MARGARET A 4 GRZYWACZ,NORBERTO M UNIVERSITY OF MIAMI SCHOOL OF MEDICINE UNIVERSITY OF SOUTHERN CALIFORNIA NIA 1 181 897 NEI 1 196 495 5R01AG024059-05 INTELLIGENT SYSTEMS FOR DETECTION OF AGING CHANGES 5 KAYE, JEFFREY A OREGON HEALTH AND SCIENCE UNIVERSITY NIA 1 213 784 1U01HL096917-01 ARIC NEUROCOGNITIVE STUDY 1 MOSLEY,THOMAS H UNIVERSITY OF MISSISSIPPI MEDICAL CENTER NHLBI 1 215 287 5R01AG030048-03 A PHASE 2 TRIAL OF AAV-NGF GENE DELIVERY IN ALZHEIMER'S DISEASE 1ZIAMH002762-14 MECHANISTIC STUDIES ON STRESS, INFLAMMATION AND NEUROPROTECTION 3 AISEN, PAUL S. UNIVERSITY OF CALIFORNIA SAN DIEGO 14 SAAVEDRA, JUAN M NATIONAL INSTITUTE OF MENTAL HEALTH NIA 1 216 259 NIMH 1 216 977 5R01AG031348-03 CITALOPRAM TREATMENT FOR AGITATION IN ALZHEIMER DEMENTIA 5U01AG033931-04 DEVELOPMENT OF CDK5 INHIBITORS 1ZIABC010959-03 RELATIONSHIP BETWEEN DNA DAMAGE DETECTION AND SIGNALING 3 LYKETSOS,CONSTANTINE G 4 KOSIK, KENNETH STEPHEN 3 NUSSENZWEIG,ANDRE JOHNS HOPKINS UNIVERSITY UNIVERSITY OF CALIFORNIA SANTA BARBARA DIVISION OF BASIC SCIENCES - NCI NIA 1 222 040 NIA 1 229 542 NCI 1 240 102

1ZIANS003122-01 MECHANISMS OF MOLECULAR MACHINES THAT REGULATE THE NEURONAL CYTOSKELETON 1 ROLL-MECAK,ANTONINA NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE NINDS 1 240 813 5R01NS041811-09 AN IMPLANTABLE DEVICE TO PREDICT AND PREVENT SEIZURES 9 DICHTER, MARC A UNIVERSITY OF PENNSYLVANIA NINDS 1 249 881 1RC4AG038804-01 COMPARATIVE EFFECTIVENESS OF DEMENTIA CARE STRATEGIES IN UNDERSERVED COMMUNITIES 5R01EY018608-02 HIGH RESOLUTION OPTOELECTRONIC RETINAL PROSTHESIS 1 VICKREY,BARBARA G 2 PALANKER,DANIEL V.RAND CORPORATION OD 1 249 939 STANFORD UNIVERSITY NEI 1 251 569 5R01HD057977-02 PROPHYLACTIC PHENOBARBITAL AFTER RESOLUTION OF NEONATAL SEIZURES 2 GUILLET, RONNIE UNIVERSITY OF ROCHESTER NICHD 1 260 994 2R01MH018501-41 NEUROCHEMICAL ACTIONS OF PSYCHOTROPIC DRUGS 41 SNYDER,SOLOMON H JOHNS HOPKINS UNIVERSITY NIMH 1 272 120 5P01NS058793-03 BIOMARKERS FOR HUNTINGTON'S DISEASE: ACCELERATING THE DEVELOPMENT OF THERAPIES 3 HERSCH, STEVEN M MASSACHUSETTS GENERAL HOSPITAL NINDS 1 279 832 5R01AG031581-12 PET, APOE & THE PRECLINICAL COURSE OF ALZHEIMER'S DISEASE 12 REIMAN, ERIC MICHAEL BANNER ALZHEIMER'S INSTITUTE NIA 1 296 640 1ZIAEY000418-07 AGE-RELATED MACULAR DEGENERATION: GENETIC VARIATIONS AND ANIMAL MODEL 7 CHAN, CHI-CHAO NATIONAL EYE INSTITUTE NEI 1 298 601 5R01AG019241-08 PREVENTION OF ALZHEIMER'S DISEAE BY VITAMIN E AND SELENIUM 8 SCHMITT,FREDERICK UNIVERSITY OF KENTUCKY NIA 1 308 085 1ZICMH002903-04 PROCUREMENT AND CHARACTERIZATION OF POSTMORTEM BRAIN TISSUE 5R01EY009859-16 GENETICS OF AGE-RELATED MACULOPATHY 4 KLEINMAN, JOEL NATIONAL INSTITUTE OF MENTAL HEALTH 16 GORIN, MICHAEL B UNIVERSITY OF CALIFORNIA LOS ANGELES NIMH 1 340 978 NEI 1 342 126 1ZIAEY000447-04 ANGIOGENIC/NEUROPROTECTIVE MOLECULES IN EYE DISEASES 4 LI, XURI NATIONAL EYE INSTITUTE NEI 1 342 304 5R01EB006385-04 DYNAMIC INVERSE SOLUTIONS FOR MULTIMODAL IMAGING 1ZIAHD000910-31 HERIDITARY NEURODEGENERATIVE STORAGE DISORDERS 5R01AG021055-08 CLINICAL AND PATHOLOGICAL STUDIES IN THE OLDEST OLD 4 BOAS, DAVID A MASSACHUSETTS GENERAL HOSPITAL 31 MUKHERJEE, ANIL B EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT 8 KAWAS, CLAUDIA H UNIVERSITY OF CALIFORNIA IRVINE NIBIB 1 367 617 NICHD 1 381 836 NIA 1 382 130 1U01NS066912-01A1 THERAUPEUTIC CANDIDATES FOR HUNTINGTON'S DISEASE: FROM LEAD TO IND 1 KAZANTSEV,ALEKSEY GREGORY MASSACHUSETTS GENERAL HOSPITAL NINDS 1 383 123 1ZIAEY000307-16 LIPID TRANSPORT, OXIDATION AND TOXICITY IN THE RETINA 16 RODRIGUEZ,IGNACIO R NATIONAL EYE INSTITUTE NEI 1 404 736 1S10RR029193-01 AN IN VIVO/IN VITRO 2-PHOTON UNCAGING/IMAGING MICROSCOPE 1 CONSTANTINE-PAT ON, MARTHA MASSACHUSETTS INSTITUTE OF TECHNOLOGY NCRR 1 415 803 5U01MH083501-03 THE MANHATTAN HIV BRAIN BANK 3 MORGELLO, SUSAN MOUNT SINAI SCHOOL OF MEDICINE NIMH 1 424 223 5R01AG021136-07 PROGRESSION OF DEMENTIA: A POPULATION STUDY 7 TSCHANZ, JOANN T UTAH STATE UNIVERSITY NIA 1 438 268 1ZIANS003051-03 CENTRAL NERVOUS SYSTEM DRUG DELIVERY TECHNIQUES 1RC3EY020749-01 AUTOMATIC EYE DISEASE SCREENING SYSTEM 3 LONSER, RUSSELL NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE 1 SOLIZ, PETER SOLIZ VISIONQUEST BIOMEDICAL, LLC NINDS 1 441 207 NEI 1 442 431 1ZIAMH002039-28 PHARMACOLOGY OF STIMULUS MEMORY AND HABIT FORMATION 28 MISHKIN,MORTIMER NATIONAL INSTITUTE OF MENTAL HEALTH NIMH 1 446 562 5U01AG006786-25 ALZHEIMERS DISEASE PATIENT REGISTRY 25 PETERSEN,RONALD C MAYO CLINIC NIA 1 455 869 5R01DC009899-02 RESTORING COMMUNICATION WITH AN INTRACORTICAL NEURAL INTERFACE SYSTEM 2 HOCHBERG,LEIGH R MASSACHUSETTS GENERAL HOSPITAL NIDCD 1 456 859 5R01AG022381-08 THE VETSA LONGITUDINAL MRI TWIN STUDY OF AGING 8 KREMEN, WILLIAM S UNIVERSITY OF CALIFORNIA SAN DIEGO NIA 1 466 956 5R01AG018384-08 THE VETSA LONGITUDINAL TWIN STUDY OF COGNITION AND AGING 8 LYONS, MICHAEL J. BOSTON UNIVERSITY NIA 1 487 213 1ZIAMH002386-24 CHEMICAL CODING OF NEUROTRANSMISSION 24 EIDEN, LEE E. NATIONAL INSTITUTE OF MENTAL HEALTH NIMH 1 493 463 1U01NS069517-01 MULTI-FUNCTIONAL NEUROPROSTHETIC SYSTEMS FOR RESTORATION OF MOTOR FUNCTION 1 PECKHAM, PAUL HUNTER CASE WESTERN RESERVE UNIVERSITY NINDS 1 497 544

2R01AG023651-06A1 MILD COGNITIVE IMPAIRMENT: A PROSPECTIVE COMMUNITY STUDY 6 GANGULI, MARY UNIVERSITY OF PITTSBURGH AT PITTSBURGH NIA 1 501 562 5R01AG028786-04 GENETIC EPIDEMIOLOGY OF ALZHEIMER'S DISEASE IN AFRICAN AMERICANS 4 MANLY, JENNIFER JAIE COLUMBIA UNIVERSITY HEALTH SCIENCES NIA 1 514 612 3U01AG022376-05A2 S1 THE LIFE STUDY 5 PAHOR, MARCO UNIVERSITY OF FLORIDA NHLBI 1 524 000 1ZIANS003031-04 PATHOPHYSIOLOGY OF BASAL GANGLIA DISORDERS 1ZIAAI000937-07 BIOLOGY OF PRION PROTEIN AND THE TSE DISEASES 1ZICMH002901-04 TRANSGENIC ANIMAL MODELS FOR NEUROSCIENCE RESEARCH 4 HALLETT, MARK NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE 7 CHESEBRO, BRUCE NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES 4 PICKEL, JAMES NATIONAL INSTITUTE OF MENTAL HEALTH NINDS 1 578 236 NIAID 1 581 907 NIMH 1 588 780 5RC2NS069476-02 DELIVERY OF THERAPEUTIC GENES IN MOTOR NEURON DISEASE 2 BURGHES, ARTHUR H. M.OHIO STATE UNIVERSITY NINDS 1 674 836 1ZIADK024950-04 BIOLOGICAL ROLES AND STRUCTURES OF YEAST PRIONS 7R01EY013516-08 ADVANCED IMAGING FOR GLAUCOMA 1ZIANS003119-01 MULTIMODAL MRI IN MULTIPLE SCLEROSIS 1ZIADK029023-20 STRUCTURE AND DYNAMICS OF MACROMOLECULES IN SOLUTION BY NMR 4 WICKNER, REED B NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES 8 HUANG, DAVID OREGON HEALTH AND SCIENCE UNIVERSITY 1 REICH, DANIEL NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE 20 CLORE, G. MARIUS NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES NIDDK 1 683 737 NEI 1 693 606 NINDS 1 715 503 NIDDK 1 719 977 1ZIAES065078-17 MOLECULAR CHARACTERIZATION OF THE MITOCHONDRIAL DNA POLYMERASE 17 COPELAND,WILLIAM NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES NIEHS 1 720 290 1ZIANS003034-04 BIOMARKERS OF PARKINSON DISEASE AND RELATED DISORDERS 4 GOLDSTEIN, DAVID NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE NINDS 1 781 723 3U01AG024904-05S7 ALZHEIMER'S DISEASE NEUROIMAGING INITIATIVE 1R24EY021126-01 PHARMACOLOGICAL TREATMENT OF RETINAL DISEASES 5RC2NS069450-02 A NOVEL MONKEY MODEL FOR PARKINSON'S DRUG DISCOVERY 1ZIANS002992-09 MOLECULAR PATHOGENESIS OF HEREDITARY SPASTIC PARAPLEGIAS 5 WEINER,MICHAEL W 1 PALCZEWSKI,KRZYSZTOF NMI 2 FEDEROFF,HOWARD J 9 BLACKSTONE,CRAIG NORTHERN CALIFORNIA INSTITUTE RES & EDUC CASE WESTERN RESERVE UNIVERSITY GEORGETOWN UNIVERSITY NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE NIA 1 900 000 NEI 1 931 032 NINDS 1 949 249 NINDS 1 954 622 1R01AG037212-01 EPIDEMIOLOGY OF BIOMARKERS OF RISK AND PROGRESSION IN LOAD 1 MAYEUX, RICHARD COLUMBIA UNIVERSITY HEALTH SCIENCES NIA 1 978 440 5R01NS052619-05 COORDINATION AND STATISTICS FOR COQ10 IN HD [2CARE]5 MCDERMOTT,MICHAEL P UNIVERSITY OF ROCHESTER NINDS 1 996 155 1ZIANR000014-05 MOLECULAR-GENETIC MECHS UNDERLYING EFFECTS OF ANTI-INFLAMMATORY/ANALGESIC DRUGS 5 WANG, XIAO-MIN NATIONAL INSTITUTE OF NURSING RESEARCH NINR 2 076 127 2U10EY017823-05 COORDINATING CENTER FOR THE COMPARISON OF AMD TREATMENTS TRIAL 1ZIAES090082-14 ROLES OF BRAIN NEUROIMMUNE SYSTEM IN NEURODEGENERATION 1RC2EY020678-01 GENOME-WIDE TARGETED GENE RESEQUENCING IN GLAUCOMA 5 MAGUIRE,MAUREEN G 14 HONG,JAU-SHYONG SHYONG 1 GAASTERLAND,THERESA UNIVERSITY OF PENNSYLVANIA NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES UNIVERSITY OF CALIFORNIA SAN DIEGO NEI 2 128 918 NIEHS 2 152 477 NEI 2 213 935 5U10EY017337-02 CHINESE AMERICAN EYE STUDY 2 VARMA, ROHIT UNIVERSITY OF SOUTHERN CALIFORNIA NEI 2 262 150 1DP2OD007483-01 DEVELOPMENT OF A CELL REPLACEMENT THERAPY TO TREAT RETINAL DEGENERATIVE BLINDNESS 1 TUCKER, BUDD ALBERT UNIVERSITY OF IOWA NEI 2 262 500 1DP2OD007472-01 BIO-IONIC NEURAL INTERFACES 1 THEOGARAJAN,LUKE SATISH KUMAR UNIVERSITY OF CALIFORNIA SANTA BARBARA OD 2 272 500 1RC3AG037357-01 CAMCI: ADVANCING THE USE OF COMPUTERIZED SCREENING IN HEALTHCARE 1 ESCHMAN, AMY PSYCHOLOGY SOFTWARE TOOLS, INC OD 2 305 646

1S10RR029249-01 DYNAMIC NUCLEAR POLARIZATION SOLID STATE NMR SPECTROMETER FOR BIOMOLECULAR STUDIE 1 MCDERMOTT,ANN E NEW YORK STRUCTURAL BIOLOGY CENTER NCRR 2 309 300 1DP2OD007265-01 IN VIVO CONTROL AND FUNCTIONAL VISUALIZATION OF STEM CELL-DRIVEN CNS REGENERATION 1 LEE, JIN HYUNG UNIVERSITY OF CALIFORNIA LOS ANGELES OD 2 310 000 1DP2OD007338-01 CLINICALLY TRANSLATABLE NANOTECHNOLOGY: HEMOSTASIS AND NEUROPROTECTION 1 LAVIK, ERIN CASE WESTERN RESERVE UNIVERSITY OD 2 355 000 1DP2OD007394-01 NANOTECHNOLOGY-BASED THERANOSTIC TECHNOLOGY FOR BONE TISSUE ENGINEERING 1 SITHARAMAN,BALAJI STATE UNIVERSITY NEW YORK STONY BROOK OD 2 355 000 1ZIAHG200336-05 "GENETIC AND CLINICAL STUDIES OF GAUCHER DISEASE AND OTHER LYSOSOMAL DISORDERS"5 SIDRANSKY, ELLEN NATIONAL HUMAN GENOME RESEARCH INSTITUTE NHGRI 2 548 636 1S10RR028893-01 ULTRA-HIGH RESOLUTION MASS SPECTROMETER FOR BIOMEDICAL RESEARCH 1 LOO, JOSEPH A UNIVERSITY OF CALIFORNIA LOS ANGELES NCRR 2 709 858 1RC3EY020792-01 NOVEL ADENO-ASSOCIATED VIRAL THERAPY FOR X-LINKED RETINITIS PIGMENTOSA 1 KOZARSKY, KAREN REGENX, LLC NEI 2 822 695 5R01EY012893-10 RESEARCH/DEVELOPMENT OF ARTIFICIAL RENTINAS FOR THE BLIND 10 GREENBERG,ROBERT JAY SECOND SIGHT MEDICAL PRODUCTS, INC.NEI 2 901 071 1RC3NS070658-01 PUTTING EEG IN THE EMERGENCY DEPARTMENT 1 OMURTAG, AHMET BIO-SIGNAL GROUP CORPORATION NINDS 2 949 240 5R24EY017404-05 DEVELOPMENT OF COMPLEMENT MODULATING THERAPEUTICS FOR AMD 5 HAGEMAN,GREGORY S UNIVERSITY OF UTAH NEI 2 986 452 1RC3AI089207-01 DEVELOPMENT OF A NOVEL BI-SPECIFIC ANTIBODY BASED THERAPEUTIC THAT SIMULTANEOUSLY 1 MOORE, PAUL ANDREW MACROGENICS, INC. NIAID 2 999 972 1RC3NS070629-01 AXONAL GROWTH THERAPY FOR NEUROLOGICAL RECOVERY FROM SPINAL CORD INJURY AND STROK 1 MCBRINN, SYLVIA AXERION THERAPEUTICS, INC.NINDS 3 000 000 1RC3EY020769-01 COMMERCIALIZATION OF ISONEP,A HUMANIZED MONOCLONAL ANTIBODY AGAINST THE BIOACTIV 1 SABBADINI, ROGER ALLEN LPATH THERAPEUTICS,INC.NEI 3 000 000 2U01NS045911-06A2 IMPACT OF INITIAL THERAPY AND RESPONSE ON LONG TERM OUTCOME IN CHILDREN WITH CAE 6 GLAUSER, TRACY A CHILDREN'S HOSPITAL MEDICAL CENTER CINCI NINDS 3 246 560 5R24EY017540-04 ADULT STEM CELLS FOR THERAPY OF VISUAL DISORDERS 4 FRIEDLANDER,MARTIN SCRIPPS RESEARCH INSTITUTE NEI 3 538 648 2PN2EY016525-07 CENTER FOR PROTEIN FOLDING MACHINERY 7 CHIU, WAH BAYLOR COLLEGE OF MEDICINE OD 3 865 000 5U01AG032984-02 ALZHEIMER'S DISEASE GENETICS CONSORTIUM 2 SCHELLENBERG,GERARD DAVID UNIVERSITY OF PENNSYLVANIA NIA 4 098 922 1RC4NS073008-01 IBIC: INTEGRATED BRAIN IMAGING CENTER FOR THE UNIVERSITY OF WASHINGTON 1 GRABOWSKI,THOMAS J UNIVERSITY OF WASHINGTON OD 4 784 830 5U01NS053998-04 THE EPILEPSY PHENOME/GENOME PROJECT (EPGP)4 LOWENSTEIN,DANIEL UNIVERSITY OF CALIFORNIA SAN FRANCISCO NINDS 5 050 178 2U01NS049640-06 CLINICAL TRIAL OF CEFTRIAXONE IN SUBJECTS WITH ALS 6 CUDKOWICZ,MERIT E MASSACHUSETTS GENERAL HOSPITAL NINDS 6 809 454 5U01AG029824-02 ASPIRIN IN REDUCING EVENTS IN THE ELDERLY 2 GRIMM, RICHARD HUGO MINNEAPOLIS MEDICAL RESEARCH FDN, INC.NIA 9 375 981

Table 2 NIH funding for Alzheimer’s disease in 2010 (Selected, with total cost over $500 000)

5R01AG034613-02 HIGH-RESOLUTION STRUCTURAL AND FUNCTIONAL BRAIN IMAGING OF THE MEDIAL TEMPORAL LO 2 STARK, CRAIG E 5R01AG019653-09 APOLIPOPROTEIN E,ATTENTION, AND ALZHEIMER'S DISEASE 9 PARASURAMAN,RAJA 1ZIADK060101-04 TARGETED DISRUPTION THE ENZYMES OF O-GLCNAC CYCLING: ANIMAL MODELS OF DISEASE 4 HANOVER, JOHN A 5R01MH080240-02 AMYLOID, WHITE MATTER HYPERINTENSITIES &OUTCOMES OF LATE-LIFE DEPRESSION 2 BUTTERS, MERYL A 1ZIAES102285-04 THYROID HORMONE SIGNALING 4 ARMSTRONG, DAVID 5R01AG025259-05 MULTI-ETHNIC GENOME-WIDE ALZHEIMER ASSOCIATION STUDY 5 FARRER, LINDSAY A 5R01NS033689-16 NEUROTROPHIC FACTOR DEPRIVATION AND NEURONAL CELL DEATH 16 GREENE, LLOYD A 1R01AG034157-01A2 METHODOLOGY ISSUES IN A TAILORED LIGHT TREATMENT FOR PERSONS WITH DEMENTIA 1 FIGUEIRO, MARIANA 5R01NS055371-05 DISRUPTED TRANSPORT OF NGF-TRKA SIGNALING IN MOUSE MODELS OF DOWN SYNDROME 5 MOBLEY, WILLIAM C 5R44AG026402-04 COMPUTERIZED EARLY DEMENTIA ASSESSMENT SYSTEM 4 O'HALLORAN,JAMES P 271201000007I-0-271 00001-1?INVESTIGATIONAL NEW DRUG TOXICOLOGY FOR DRUGS TO TREAT AD & OTHER AGING-RELATED Unavailable 5R01AG032132-16 CONTROL OF AMPA RECEPTOR TRAFFICKING BY BETA AMYLOID 16 MALINOW,ROBERTO 1U01AG033183-01A2 EFFICACIOUS AND SAFE ANTIBODY CATALYZED AMYLOID BETA CLEARANCE 1 PAUL, SUDHIR 4R37AG024102-06 MIDLIFE COGNITIVE CHANGE AND RISK OF COGNITIVE DECLINE 6 WILLIS, SHERRY L 1R01AG033613-01A1 LIPOIC ACID AND OMEGA-3 FATTY ACIDS IN ALZHEIMER'S DISEASE 1 SHINTO, LYNNE H 1R01AG036755-01A1 A LARGE RANDOMIZED TRIAL OF VITAMIN D, OMEGA-3 FATTY ACIDS AND COGNITIVE DECLINE 1 KANG, JAE H 5R01MH078821-17 MOLECULAR GENETIC APPROACHES TO LEARNING AND MEMORY 17 TONEGAWA,SUSUMU 1ZIANS003106-02 ROLES OF CDK5 IN NEURODEVELOPMENT AND NEURODEGENERATION 2 GINIGER, EDWARD 5R01AG032349-03 TOLL-LIKE RECEPTOR SIGNALING IN ALZHEIMER'S DISEASE 3 EL-KHOURY,JOSEPH 5R01AG005213-21 EFFECTS OF AGE ON THE COGNITIVE ERPD/CARDIAC WAVE EFFECT 21 FRIEDMAN, DAVID 5R01AG032276-02 SINGLE MOLECULE APPROACH TO NEURODEGENERATION IN ALZHEIMER'S DISEASE 2 GAFNI, ARI 1R01AG035361-01A1 NOVEL GABA-A MODULATORS AS COGNITIVE ENHANCERS 1 ROWLETT, JAMES K 5R01AG034556-02 NEURAL PROCESSES UNDERLYING COGNITIVE AGING 2 BUCKNER, RANDY L 1R01AG033581-01A2 CONVERSATIONAL ENGAGEMENT AS A MEANS TO DELAY ALZHEIMER'S DISEASE ONSET 1 DODGE, HIROKO HAYAMA UNIVERSITY OF CALIFORNIA IRVINE NIA 503 947 NIA 506 699 NIDDK 507 288 NIMH 507 714 NIEHS 512 837 NIA 513 537 NINDS 516 891 NIA 517 629 NINDS 518 723 NIA 519 014 NIA 521 234 NIA 525 158 NIA 528 773 NIA 530 857 NIA 532 428 NIA 535 208 NIMH 538 354 NINDS 538 425 NIA 539 021 NIA 540 318 NIA 541 682 NIA 542 446 NIA 547 348 NIA 548 846 GEORGE MASON UNIVERSITY NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES UNIVERSITY OF PITTSBURGH AT PITTSBURGH NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES BOSTON UNIVERSITY MEDICAL CAMPUS COLUMBIA UNIVERSITY HEALTH SCIENCES RENSSELAER POLYTECHNIC INSTITUTE UNIVERSITY OF CALIFORNIA SAN DIEGO NEUROCOMP SYSTEMS,INC. UNIVERSITY OF CALIFORNIA SAN DIEGO UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON UNIVERSITY OF WASHINGTON OREGON HEALTH AND SCIENCE UNIVERSITY BRIGHAM AND WOMEN'S HOSPITAL MASSACHUSETTS INSTITUTE OF TECHNOLOGY NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE MASSACHUSETTS GENERAL HOSPITAL COLUMBIA UNIVERSITY HEALTH SCIENCES UNIVERSITY OF MICHIGAN AT ANN ARBOR HARVARD UNIVERSITY(MEDICAL SCHOOL)MASSACHUSETTS GENERAL HOSPITAL OREGON HEALTH AND SCIENCE UNIVERSITY

5R01AG026096-05 CIND: RISK FACTORS FOR CONVERSION TO DEMENTIA 5 UNVERZAGT,FREDERICK W 2R01AG021927-06A1 FUNCTIONAL CHANGE IN MILD COGNITIVE IMPAIRMENT 6 MARSON, DANIEL C 5R01AG029672-04 IMPROVING COGNITIVE OUTCOME PRECISION &RESPONSIVENESS WITH MODERN PSYCHOMETRICS 4 CRANE, PAUL K 2R01AG026484-06A1 VASCULAR DYSFUNCTION IN CEREBRAL AMYLOID ANGIOPATHY 6 GREENBERG,STEVEN M 5U01AG031106-03 NOVEL HSP90 INHIBITORS TO REDUCE MISFOLDED PROTEINS IN ALZHEIMER'S DISEASE 3 MICHAELIS, MARY L.5R01HD065160-02 PREDICTING COGNITIVE DECLINE IN ADULTS WITH DOWN SYNDROME 2 LOTT, IRA T 1R01HL102457-01 ARTERIAL AGING, BRAIN PERFUSION & EXERCISE:IMPACT ON BRAIN STRUCTURE& FUNCTION.1 ZHANG, RONG 5R01AG019604-08 EXPLAINING DISPARITIES IN COGNITIVE FUNCTION IN SENIORS 8 SCHWARTZ,BRIAN S 5P30AG036449-02 FACULTY RECRUITMENT FOR PROGRAMS IN THE BIOLOGY OF AGE-RELATED COGNITIVE CHANGE 2 HYMAN, BRADLEY T 5R01AG027424-02 HIPPOCAMPAL MICROSTRUCTURE AND FUNCTION IN APP TG MICE 2 WYRWICZ, ALICE M 1ZIAHG200335-05 THE INFLUENCE OF FAMILIAL SOCIAL CONTEXT ON RISK DISSEMINATION AND COPING 5 KOEHLY, LAURA 5R01AG006656-20 CHAT, ACHE, AND CHOLINERGIC NEURONS IN AGING AND AD 20 YOUNKIN, STEVEN G 5R01AG024180-05 MCI, INSULIN AND CHOLESTEROL IN A COMMUNITY SAMPLE 5 CRAFT, SUZANNE 5R01HD057564-03 PERINATAL CHOLINE THERAPY IN A MOUSE MODEL OF DOWN SYNDROME & ALZHEIMER'S DISEASE 3 STRUPP, BARBARA J 5R01AG027472-05 THE MIND ICU STUDY 5 ELY, E WESLEY 5R01AG028076-02 CEREBROMICROVASCULAR DISEASE IN ELDERLY WITH DIABETES 2 NOVAK, VERA 2R01AG021028-06A2 HETEROGENEITY OF MILD COGNITIVE IMPAIRMENT (MCI)6 DECARLI, CHARLES 5R01AG010220-15 ENGLISH AND SPANISH ASSESSMENT OF COGNITION IN ELDERLY 15 MUNGAS, DAN M 2R01HG002213-10 RISK EVALUATION AND EDUCATION FOR ALZHEIMER'S DISEASE (REVEAL IV)10 GREEN, ROBERT C 5R01NS050537-07 ROLE OF FIBRIN IN ALZHEIMER'S DISEASE 7 STRICKLAND,SIDNEY 4R37AG011230-16 NEURAL CORRELATES AND MODIFIERS OF COGNITIVE AGING 16 RAZ, NAFTALI 5R01AG030114-02 THERAPEUTIC EFFECTS OF CATARACT REMOVAL IN ALZHEIMER'S DISEASE 2 GILMORE, GROVER CLEVELAND 1R01ES019282-01 NEUROTOXICITY OF ORGANOPHOSPHORUS PESTICIDES IN DEVELOPING GUINEA PIGS 1 ALBUQUERQUE,EDSON X 5R42AG023443-05 ANTI-AGING MITOCHONDRIAL PROTEIN THERAPY FOR ALZHEIMER?S DISEASE AND SARCOPENIA 5 BENNETT, JAMES PEPPER 1R01AG035025-01A1 PREVENTING COGNITIVE DECLINE IN AFRICAN AMERICANS WITH MILD COGNITIVE IMPAIRMENT.1 ROVNER, BARRY W 5R01AG030155-04 THE COST OF DEMENTIA 4 HURD, MICHAEL D INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS NIA 552 490 NIA 554 173 NIA 557 232 NIA 557 292 NIA 558 423 NICHD 558 918 NHLBI 568 704 NIA 575 248 NIA 575 250 NIA 577 672 NHGRI 584 894 NIA 585 182 NIA 585 463 NICHD 588 346 NIA 591 365 NIA 592 598 NIA 595 777 NIA 598 988 NHGRI 601 513 NINDS 603 457 NIA 607 994 NIA 612 414 NIEHS 614 700 NIA 614 734 NIA 620 120 NIA 622 814 UNIVERSITY OF ALABAMA AT BIRMINGHAM UNIVERSITY OF WASHINGTON MASSACHUSETTS GENERAL HOSPITAL UNIVERSITY OF KANSAS LAWRENCE UNIVERSITY OF CALIFORNIA IRVINE UNIVERSITY OF TEXAS SW MED CTR/DALLAS JOHNS HOPKINS UNIVERSITY MASSACHUSETTS GENERAL HOSPITAL NORTHSHORE UNIV HEALTHSYSTEM RES INST NATIONAL HUMAN GENOME RESEARCH INSTITUTE MAYO CLINIC JACKSONVILLE SEATTLE INST FOR BIOMEDICAL/CLINICAL RES CORNELL UNIVERSITY ITHACABETH ISRAEL DEACONESS MEDICAL CENTER UNIVERSITY OF CALIFORNIA DAVIS UNIVERSITY OF CALIFORNIA DAVIS BOSTON UNIVERSITY MEDICAL CAMPUS ROCKEFELLER UNIVERSITY WAYNE STATE UNIVERSITY CASE WESTERN RESERVE UNIVERSITY UNIVERSITY OF MARYLAND BALTIMORE GENCIA CORPORATION THOMAS JEFFERSON UNIVERSITY

5R01GM090311-02 NOVEL MITOCHONDRIALLY ENCODED PEPTIDES AND THEIR ROLE IN HEALTH AND DISEASE 5R01AG034087-02 INFLAMMATION, LONG-TERM DIABETES CHARACTERISTICS,AND COGNITIVE DECLINE 5U01AG029213-03 ALZHELMER'S DISEASE DRUG DEVELOPMENT PROGRAM 5R01AG016324-07 BRAIN IMAGING & COGNITION IN SUBJECTS AT RISK FOR ALZHEIMER'S DISEASE 1S10RR029663-01 A MULTIPHOTON MICROSCOPE FOR TRANSLATIONAL AND BASIC BIOMEDICAL RESEARCH 5R01AG028144-04 PATHWAYS FROM STRESS TO METABOLIC SYNDROME AND HEALTH DECLINE IN AGED CAREGIVERS 5R01AG034570-02 NEURAL AND BIOCHEMICAL MECHANISMS OF COGNITIVE AGING 5R01AG031222-02 MODELING ALZHEIMER DISEASE COSTS AND TRANSITIONS 5R01DC009977-02 SENSELAB: INTEGRATION OF MULTIDISCIPLINARY SENSORY DATA 5RC2AG036419-02 BRIDGING COGNITIVE AGING IN RODENTS TO MAN USING FMRI IN AMNESTIC MCI 2R01AG012101-16A2 MRI PROGRESSION MARKERS OF COGNITIVE DECLINE IN THE ELDERLY 5RC2AG036614-02 NEURODEGENERATION AND SYNAPTIC TRANSMISSION IN AGING 1R01AG033288-01A1 ESTROGEN RECEPTOR-BETA PHYTOSERMS FOR MANAGEMENT OF MENOPAUSE AND AGE-ASSOCIATED 1ZIABC010440-09 PROTEIN STRUCTURE,STABILITY, AND AMYLOID FORMATION 1R01AG037497-01 CHARACTERIZING THE EVOLUTION OF AMYLOID DEPOSITION IN NORMAL ELDERLY 1U01HL096902-01 ARIC NEUROCOGNITIVE STUDY(ARIC-NCS)5R01AG033032-02 APATHY IN ALZHEIMER'S DISEASE METHYLPHENIDATE TRIAL 1ZIAAG000966-03 NEUROIMAGING, BEHAVIORAL NEUROLOGY AND DEVELOPMENT OF 3T MRI PROJECTS 1R01MH086881-01A1 GERIATRIC DEPRESSION: PET STUDIES OF PATHOPHYSIOLOGY AND TREATMENT RESPONSE 5R01AG027161-04 WISCONSIN REGISTRY FOR ALZHEIMER PREVENTION:BIOMARKERS OF PRECLINICAL AD 5R37GM042056-22 STRUCTURAL IDENTIFICATION OF PROSTAGLANDIN CONJUGATES 1ZIAAG000312-10 CELLULAR AND MOLECULAR PATHOGENESIS OF ALZHEIMER 2R01AG022018-06A1 RISK FACTORS FOR COGNITIVE DECLINE IN AFRICAN-AMERICANS 1U01AG032969-01A1 SMALL MOLECULE HSP90 INHIBITORS IN AD TREATMENT 2 COHEN, PINCHAS 2 SCHNAIDER BEERI,MICHAL 3 SMITH, AMOS B 7 BASSETT, SUSAN SPEAR 1 MAXFIELD,FREDERICK R 4 FREDMAN, LISA 2 JAGUST, WILLIAM J 2 CALLAHAN,CHRISTOPHER M 2 SHEPHERD,GORDON MURRAY 2 GALLAGHER,MICHELA 16 DE LEON, MONY J 2 SHEN, JIE 1 SCHNEIDER, LON S 9 NUSSINOV, RUTH 1 JOHNSON, KEITH A 1 ALONSO, ALVARO 2 MINTZER,JACOBO E.3 EGAN, JOSEPHINE 1 SMITH, GWENN S 4 SAGER, MARK 22 ROBERTS, L JACKSON 10 MATTSON, MARK 6 BARNES, LISA L 1 CHIOSIS, GABRIELA UNIVERSITY OF CALIFORNIA LOS ANGELES OD 626 685 NIA 628 130 NIA 634 310 NIA 634 682 NCRR 638 318 NIA 644 239 NIA 659 774 NIA 666 786 NIDCD 669 843 NIA 676 643 NIA 678 660 NIA 680 100 NIA 686 664 NCI 689 125 NIA 694 513 NHLBI 696 076 NIA 709 569 NIA 711 883 NIMH 716 137 NIA 721 917 NIGMS 726 997 NIA 734 338 NIA 737 372 NIA 738 284 MOUNT SINAI SCHOOL OF MEDICINE UNIVERSITY OF PENNSYLVANIA JOHNS HOPKINS UNIVERSITY WEILL MEDICAL COLLEGE OF CORNELL UNIV BOSTON UNIVERSITY MEDICAL CAMPUS UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS YALE UNIVERSITY JOHNS HOPKINS UNIVERSITY NEW YORK UNIVERSITY SCHOOL OF MEDICINE BRIGHAM AND WOMEN'S HOSPITAL UNIVERSITY OF SOUTHERN CALIFORNIA DIVISION OF BASIC SCIENCES - NCI MASSACHUSETTS GENERAL HOSPITAL UNIVERSITY OF MINNESOTA TWIN CITIES MEDICAL UNIVERSITY OF SOUTH CAROLINA NATIONAL INSTITUTE ON AGING JOHNS HOPKINS UNIVERSITY UNIVERSITY OF WISCONSIN MADISON VANDERBILT UNIVERSITY NATIONAL INSTITUTE ON AGING RUSH UNIVERSITY MEDICAL CENTER SLOAN-KETTERING INSTITUTE FOR CANCER RES

5R01AG015116-12 CONCEPTUAL PROCESSING IN ALZHEIMER'S DISEASE 1U01NS065102-01A1 DEVELOPMENT AND TESTING OF HSP90 INHIBITORS 5R01AG030653-02 SEARCH FOR THE ALZHEIMER'S GENE ON CHROMOSOME 10 1ZIAAG000311-10 DESIGN AND DEVELOPMENT OF EXPERIMENTAL THERAPEUTICS 1ZIANS002725-24 PROTEIN PHOSPHORYLATION AND REGULATION OF CYTOSKELETON IN NEURONAL SYSTEMS 5R01AG031553-03 EPIDEMIOLOGIC STUDY OF BRAIN VITAMIN E, DIET &AGE-RELATED NEUROLOGIC DISEASES 1ZIAAR041157-04 STRUCTURAL BIOLOGY OF AMYLOID AND AMYLOID-LIKE PROTEINS 1DP1OD006850-01 HYPOTHALAMIC AGRP NEURONS ARE DETERMINANTS OF HEALTHY LIFESPAN AND HIGHER BRAIN F 5R01CA129769-02 OLDER BREAST CANCER PATIENTS: RISK FOR COGNITIVE DECLINE 5U01AG032225-04 P75 SMALL MOLECULE LIGANDS FOR ALZHEIMER'S THERAPY 5R01AG034155-02 STUDY ON THALIDOMIDE AS BACE1 INHIBITOR IN ALZHIEMER'S DISEASE 5R01AG017761-14 QUESTIONABLE DEMENTIA:COURSE AND PREDICTORS OF OUTCOME 5R01AG007370-20 PREDICTORS OF SEVERITY IN ALZHEIMER'S DISEASE 3P50AG025711-05S1 FLORIDA ALZHEIMER'S DISEASE RESEARCH 5R01AG031110-02 NATURAL HISTORY OF AMYLOID DEPOSITION IN ADULTS WITH DOWN SYNDROME 5RC2AG036502-02 IMAGING NEUROINFLAMMATION IN ALZHEIMER'S DISEASE (AD)WITH [11C]ARACHIDONIC ACI 3P50AG008671-20S1 MICHIGAN ALZHEIMER'S DISEASE RESEARCH CENTER 5U01HG004610-04 DEVELOPMENT AND USE OF NETWORK INFRASTRUCTURE FOR HIGH-THROUGHPUT GWA STUDIES 3P30AG012300-16S1 NEUROBIOLOGY OF ALZHEIMER'S DISEASE AND AGING 2R44AG029777-02A1 HIGH THROUGHPUT TAU OLIGOMER ASSAY FOR DRUG SCREENING FOR ALZHEIMER'S DISEASE 5R01AG009956-19 INDIANAPOLIS-IBADAN DEMENTIA PROJECT 1RC4AG038825-01 ASSESSING EARLY ALZHEIMER AND AT-RISK GROUPS WITH PATIENT REPORTED OUTCOMES 5R44AG029670-04 LEPTIN AS A THERAPY FOR ALZHEIMER'S DISEASE 5U24AG021886-09 NATIONAL CELL REPOSITORY FOR ALZHEIMER'S DISEASE 5R01AG031517-02 EFFECTS OF STANDARDIZED AEROBIC EXERCISE-TRAINING ON NEUROCOGNITIVE AND NEURODEGE 5U01AG017155-10 EPIDEMIOLOGY OF AGING AND DEMENTIA-AUTOPSY RESEARCH 12 GROSSMAN,MURRAY 1 PETRUCELLI,LEONARD 2 KAMBOH, M. ILYAS 10 GREIG, NIGEL H 24 PANT, HARISH C 3 MORRIS, MARTHA CLARE 4 STEVEN, ALASDAIR 1 HORVATH, TAMAS L 2 MANDELBLATT,JEANNE 4 LONGO, FRANK M 2 SABBAGH,MARWAN N 14 DEVANAND,DAVANGERE P 20 STERN, YAAKOV 5 POTTER,HUNTINGTON 2 HANDEN,BENJAMIN L 2 VALLABHAJOSULA,SHANKAR 20 GILMAN, SID 4 LARSON, ERIC B 16 ROSEN, ROGER NEWMAN 2 MOE, JAMES G 19 HALL, KATHLEEN S 1 SMYTH, KATHLEEN ANNE 4 TEZAPSIDIS,NIKOLAOS 9 FOROUD,TATIANA M 2 OBISESAN,THOMAS O 10 WHITE, LON RAY UNIVERSITY OF PENNSYLVANIA NIA 742 965 NINDS 746 857 NIA 748 287 NIA 784 982 NINDS 800 720 NIA 803 711 NIAMS 803 844 OD 827 500 NCI 833 064 NIA 835 642 NIA 839 712 NIA 851 817 NIA 857 341 NIA 875 000 NIA 879 621 NIA 886 509 NIA 888 692 NHGRI 889 184 NIA 895 000 NIA 917 397 NIA 933 797 OD 942 573 NIA 944 180 NIA 945 143 NIA 962 241 NIA 991 717 MAYO CLINIC JACKSONVILLE UNIVERSITY OF PITTSBURGH AT PITTSBURGH NATIONAL INSTITUTE ON AGING NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE RUSH UNIVERSITY MEDICAL CENTER NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES YALE UNIVERSITY GEORGETOWN UNIVERSITY STANFORD UNIVERSITY SUN HEALTH RESEARCH INSTITUTE COLUMBIA UNIVERSITY HEALTH SCIENCES COLUMBIA UNIVERSITY HEALTH SCIENCES UNIVERSITY OF SOUTH FLORIDA UNIVERSITY OF PITTSBURGH AT PITTSBURGH WEILL MEDICAL COLLEGE OF CORNELL UNIV UNIVERSITY OF MICHIGAN AT ANN ARBOR GROUP HEALTH COOPERATIVE UNIVERSITY OF TEXAS SW MED CTR/DALLAS OLIGOMERIX, INC INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS CASE WESTERN RESERVE UNIVERSITY NEUROTEZ, INC.INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS HOWARD UNIVERSITY KUAKINI MEDICAL CENTER

5R44AG025641-05 MONOCLONAL ANTIBODIES FOR ALZHEIMER'S IMMUNOTHERAPY 5 HIATT, ANDREW 1RC3RR030793-01 EXPANDING F-18 PRODUCTION FOR PET/CT 1 WIELAND, BRUCE WENDELL 5R01AG011378-18 IDENTIFYING MECHANISMS OF DEMENTIA: ROLE FOR MRI IN THE ERA OF MOLECULAR IMAGING 18 JACK, CLIFFORD ROBERT 5R01AG012975-13 EPIDEMIOLOGY OF FUNCTIONAL STATUS IN ELDERLY HISPANICS 13 HAAN, MARY N 5R01AG019085-09 GENETIC STUDIES OF DEMENTIA IN THE AMISH 9 HAINES,JONATHAN L 5R01AG027944-03 GENOMIC CONVERGENCE IN ALZHEIMER DISEASE 3 PERICAK-VANCE,MARGARET A 5R01AG024059-05 INTELLIGENT SYSTEMS FOR DETECTION OF AGING CHANGES 5 KAYE, JEFFREY A 1U01HL096917-01 ARIC NEUROCOGNITIVE STUDY 1 MOSLEY, THOMAS H 5R01AG030048-03 A PHASE 2 TRIAL OF AAV-NGF GENE DELIVERY IN ALZHEIMER'S DISEASE 3 AISEN, PAUL S 1ZIAMH002762-14 MECHANISTIC STUDIES ON STRESS, INFLAMMATION AND NEUROPROTECTION 14 SAAVEDRA, JUAN M 5R01AG031348-03 CITALOPRAM TREATMENT FOR AGITATION IN ALZHEIMER DEMENTIA 3 LYKETSOS,CONSTANTINE G 5R01AG031892-02 WHITE MATTER DAMAGE IN AGE-RELATED COGNITIVE DECLINE 2 MONTINE,THOMAS J 1RC4AG038804-01 COMPARATIVE EFFECTIVENESS OF DEMENTIA CARE STRATEGIES IN UNDERSERVED COMMUNITIES 1 VICKREY,BARBARA G 5R01AG019241-08 PREVENTION OF ALZHEIMER'S DISEAE BY VITAMIN E AND SELENIUM 8 SCHMITT,FREDERICK 5R01AG018386-08 THE VETSA LONGITUDINAL TWIN STUDY OF COGNITION AND AGING 8 KREMEN, WILLIAM S 2R01AG008122-21 EPIDEMIOLOGY OF DEMENTIA IN THE FRAMINGHAM STUDY 21 WOLF, PHILIP A 5R01AG021136-07 PROGRESSION OF DEMENTIA: A POPULATION STUDY 7 TSCHANZ, JOANN T 1ZIAMH002039-28 PHARMACOLOGY OF STIMULUS MEMORY AND HABIT FORMATION 28 MISHKIN, MORTIMER 5U01AG006786-25 ALZHEIMERS DISEASE PATIENT REGISTRY 25 PETERSEN,RONALD C 1ZIAMH002386-24 CHEMICAL CODING OF NEUROTRANSMISSION 24 EIDEN, LEE E.5R01AG028786-04 GENETIC EPIDEMIOLOGY OF ALZHEIMER'S DISEASE IN AFRICAN AMERICANS 4 MANLY, JENNIFER JAIE 3U01AG022376-05A2 S1 THE LIFE STUDY 5 PAHOR, MARCO 1ZIADK029023-20 STRUCTURE AND DYNAMICS OF MACROMOLECULES IN SOLUTION BY NMR 20 CLORE, G. MARIUS 2P50AG005146-27 JOHNS HOPKINS ALZHEIMER'S DISEASE RESEARCH CENTER 27 ALBERT, MARILYN B 1R01AG037212-01 EPIDEMIOLOGY OF BIOMARKERS OF RISK AND PROGRESSION IN LOAD 1 MAYEUX, RICHARD 1RC3AG037357-01 CAMCI: ADVANCING THE USE OF COMPUTERIZED SCREENING IN HEALTHCARE 1 ESCHMAN, AMY 1ZIAHD001607-19 PROTEIN TRAFFICKING IN THE ENDOSOMAL-LYSOSOMAL SYSTEM 19 BONIFACINO, JUAN MAPP BIOPHARMACEUTICAL,INC.NIA 1 023 870 NCRR 1 034 435 NIA 1 034 999 NIA 1 072 817 NIA 1 152 003 NIA 1 181 897 NIA 1 213 784 NHLBI 1 215 287 NIA 1 216 259 NIMH 1 216 977 NIA 1 222 040 NIA 1 249 219 OD 1 249 939 NIA 1 308 085 NIA 1 326 454 NIA 1 371 239 NIA 1 438 268 NIMH 1 446 562 NIA 1 455 869 NIMH 1 493 463 NIA 1 514 612 NHLBI 1 524 000 NIDDK 1 719 977 NIA 1 900 191 NIA 1 978 440 OD 2 305 646 NICHD 2 316 879 BRUCE TECHNOLOGIES,INC.MAYO CLINIC UNIVERSITY OF CALIFORNIA SAN FRANCISCO VANDERBILT UNIVERSITY UNIVERSITY OF MIAMI SCHOOL OF MEDICINE OREGON HEALTH AND SCIENCE UNIVERSITY UNIVERSITY OF MISSISSIPPI MEDICAL CENTER UNIVERSITY OF CALIFORNIA SAN DIEGO NATIONAL INSTITUTE OF MENTAL HEALTH JOHNS HOPKINS UNIVERSITY UNIVERSITY OF WASHINGTON RAND CORPORATION UNIVERSITY OF KENTUCKY UNIVERSITY OF CALIFORNIA SAN DIEGO BOSTON UNIVERSITY MEDICAL CAMPUS UTAH STATE UNIVERSITY NATIONAL INSTITUTE OF MENTAL HEALTH MAYO CLINIC NATIONAL INSTITUTE OF MENTAL HEALTH COLUMBIA UNIVERSITY HEALTH SCIENCES UNIVERSITY OF FLORIDA NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES JOHNS HOPKINS UNIVERSITY COLUMBIA UNIVERSITY HEALTH SCIENCES PSYCHOLOGY SOFTWARE TOOLS, INC.EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT

2P50AG005681-27 ALZHEIMERS DISEASE RESEARCH CENTER 1S10RR029233-01 THE GE PETTRACE CYCLOTRON: A SCIENTIFIC RESOURCE FOR THE STATE OF ARIZONA 5U01AG016976-12 NATIONAL ALZHEIMER'S COORDINATING CENTER(NACC)5U01AG029824-02 ASPIRIN IN REDUCING EVENTS IN THE ELDERLY 27 MORRIS, JOHN 1 REIMAN, ERIC MICHAEL 12 KUKULL, WALTER ANTHONY 2 GRIMM, RICHARD HUGO WASHINGTON UNIVERSITY NIA 2 570 270 NCRR 2 652 275 NIA 3 327 380 NIA 9 375 981 BANNER ALZHEIMER'S INSTITUTE UNIVERSITY OF WASHINGTON MINNEAPOLIS MEDICAL RESEARCH FDN, INC.

Table 3 NIH funding for Parkinson's disease in 2010 (Selected, with total cost over $500 000)

4U01NS050095-06 PARKINSON'S DISEASE DATA ORGANIZING CENTER 7R01ES010751-10 MOLECULAR EPIDEMIOLOGY OF PARKINSON'S DISEASE 6 KURLAN, ROGER M UNIVERSITY OF ROCHESTER 10 MARAGANORE,DEMETRIUS MICHAEL NORTHSHORE UNIV HEALTHSYSTEM RES INST NINDS 1 137 270 NIEHS 1 146 714 1ZIANS002139-36 PHARMACOLOGY AND PHYSIOLOGY OF THE SUBSTANTIA NIGRA AND BASAL GANGLIA Y2AG9075-26-0-1 ASSESSMENT OF PRIMATE AGING: EFFECTS OF CALORIC MODIFICATION 36 WALTERS, JUDITH RICHMOND NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE NINDS 1 153 296 Unavailable NIA 1 290 716 5R01AG017917-08 EPIDEMIOLOGIC STUDY OF NEURAL RESERVE AND NEUROBIOLOGY OF AGING 1ZIANS002859-19 PROGRAMMED CELL DEATH IN THE NERVOUS SYSTEM 1ZIAES090082-14 ROLES OF BRAIN NEUROIMMUNE SYSTEM IN NEURODEGENERATION 1ZIAES090089-14 MODULATION OF NEURONAL CHANNELS AND RECEPTORS IN THE BRAIN 5U01NS043128-09 NEUROPROTECTION STUDIES IN PD: A COORDINATING CENTER 1ZIAHG200336-05 "GENETIC AND CLINICAL STUDIES OF GAUCHER DISEASE AND OTHER LYSOSOMAL DISORDERS"8 BENNETT, DAVID ALAN RUSH UNIVERSITY MEDICAL CENTER 19 YOULE, RICHARD J NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE 14 HONG, JAU-SHYONG SHYONG NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES 14 YAKEL, JERREL L NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES 9 KIEBURTZ, KARL D UNIVERSITY OF ROCHESTER 5 SIDRANSKY, ELLEN NATIONAL HUMAN GENOME RESEARCH INSTITUTE NIA 1 663 638 NINDS 2 028 292 NIEHS 2 152 477 NIEHS 2 238 386 NINDS 2 533 926 NHGRI 2 548 636

Sources:

1. National Institutes of Health. About NIH. http://www.nih.gov/. Accessed 5 August 2011.

2. Research Portfolio Online Reporting Tools. Estimates of Funding for Various Research, Condition, and Disease Categories.

http://www.report.nih.gov/rcdc/categories/default.aspx. Accessed 5 August 2011.

3. Research Portfolio Online Reporting Tools. Search results.

http://projectreporter.nih.gov/reporterapi.cfm?k=ja98734nqlonc983qlnq8dq83y&i=%252E7WH%252FDXZZTI%2526GM%255D%253DX%2520%255C%2520%2520%250A&IC_codes=All&fy=2010&DC_codes=793. Accessed 5 August 2011.