2018年第28卷1～12期

第1期

研究報(bào)告

不同方法制備大鼠宮內(nèi)發(fā)育遲緩模型的比較 高琳琳，王軍，李子英，等(1)

腺嘌呤誘導(dǎo)慢性腎臟病大鼠模型的骨與礦物質(zhì)代謝異常 孟彥，張豪，賀寧，等(8)

組胺對(duì)抑郁癥大鼠運(yùn)動(dòng)欲望與空間記憶能力的影響 何葉成，姚娟，陳尚，等(16)

芎歸六君子湯對(duì)實(shí)驗(yàn)性大鼠冠心病的治療作用 鄭麗莉(23)

促紅細(xì)胞生成素在缺氧缺血性腦病大鼠模型中的神經(jīng)保護(hù)作用 段淼，曹云濤，王旭芹(28)

不同性別氟中毒大鼠模型的比較研究 劉洋，韓倫英，何川，等(33)

環(huán)磷酰胺誘導(dǎo)家兔卵巢早衰動(dòng)物模型的建立和評(píng)價(jià) 張娟，周月希，刁波，等(38)

苦參堿和氧化苦參堿體內(nèi)外模型的肝毒性比較研究 郭秋平，陳貴英，周泉，等(44)

大鼠尾部血管的解剖結(jié)構(gòu)與鼠尾的生理功能探討 王蕾，葉明霞(51)

大鼠壓瘡局部不同干預(yù)溫度對(duì)內(nèi)質(zhì)網(wǎng)應(yīng)激及細(xì)胞凋亡的影響 王晴，杜曉菲，邢鳳梅，等(56)

Tempol對(duì)心肌肥厚大鼠NF-κB信號(hào)通路的影響 劉撿娣，謝龍，肖坤，等(64)

CMAH基因在小鼠不同組織中的轉(zhuǎn)錄水平分析 李一帆，楊娜，王瑤，等(70)

大鼠門靜脈高壓對(duì)血清內(nèi)毒素及腸黏膜的影響分析 李曉娟，張巧云，馮帆，等(76)

復(fù)合麻醉對(duì)五指山小型豬長(zhǎng)達(dá)8小時(shí)實(shí)驗(yàn)的麻醉效果觀察 段天兵，張金霞，向定成，等(80)

技術(shù)方法

塞曼原子吸收汞分析儀測(cè)定尿汞的方法學(xué)評(píng)價(jià) 周穎，王瑩，黃海(86)

負(fù)壓吸引裝置抽取大鼠腦脊液方法的改良 王偉，李東斌，羅秀梅，等(91)

棕背鼠平性別的快速鑒定 馬芹，王元智，陸濤峰，等(96)

應(yīng)用植入遙測(cè)技術(shù)對(duì)恒河猴部分生理指標(biāo)的觀測(cè) 盧祺炯，陳敏華，徐聰，等(100)

經(jīng)驗(yàn)交流

針刺治療慢性心肌缺血小型豬模型系列方法的可行性探討 張金鈴，田毅，榮培晶，等(108)

研究進(jìn)展

腦內(nèi)表達(dá)的CYP450基因參與內(nèi)源性物質(zhì)代謝研究進(jìn)展 楊辛蘭，呂丹，張連峰(113)

人源性腫瘤組織原位異種移植模型的特征及研究策略 陳薛，張賀，師長(zhǎng)宏(118)

P301L突變tau蛋白轉(zhuǎn)基因動(dòng)物模型及其應(yīng)用 馬登磊，張如意，李林(123)

專家問答

BSA + SEB制作小鼠IgA腎病模型的注意事項(xiàng) (90)

小鼠尾靜脈注射技巧 (112)

第2期

研究報(bào)告

TRPV4受體對(duì)血管緊張素II誘導(dǎo)的小鼠腎損害的影響 閆鳳娜，劉素曉，崔琳，等(1)

血栓通膠囊對(duì)氧糖剝奪/復(fù)氧致 HUVEC 細(xì)胞緊密連接損傷的改善作用 楊愛玲，武汀，張?zhí)祛?，?7)

A型肉毒素重鏈干預(yù)對(duì)大鼠脊髓損傷后生長(zhǎng)相關(guān)蛋白表達(dá)的影響 王亞芳，蘭婧，劉福，等(12)

維生素D缺乏對(duì)自發(fā)性糖尿病大鼠發(fā)病的影響 李艷艷，王寧，劉妍妍，等(20)

白消安對(duì)小鼠造血干細(xì)胞功能的損傷作用 李程程，管博文，蘇路，等(26)

高血壓合并高脂血癥大鼠模型的實(shí)驗(yàn)研究 趙勝楠，何黎黎，李自強(qiáng)，等(33)

isthmin1對(duì)斑馬魚胚胎匯聚延伸運(yùn)動(dòng)的影響 王政，李金鵬，閆一芳，等(40)

全反式維甲酸誘導(dǎo)經(jīng)典型霍奇金淋巴瘤B細(xì)胞表型 杜靜，宮凱凱，楊麗娟，等(46)

髓芯減壓聯(lián)合富血小板血漿對(duì)兔激素性股骨頭壞死的療效及對(duì)金屬蛋白酶/基質(zhì)金屬蛋白酶組織抑制劑系統(tǒng)的影響 于鵬，紀(jì)志華，賈丙申，等(53)

全長(zhǎng)與成熟形式IL-37b的真核表達(dá)載體的構(gòu)建與研究 李夢(mèng)媛，韋榮飛，楊星九，等(59)

飛龍掌血提取物對(duì)高脂血癥心肌缺血大鼠炎癥因子的影響 劉明，劉楊，鄧穎，等(64)

大鼠Pig-a基因突變?cè)囼?yàn)中N-乙基-N-亞硝基脲和環(huán)磷酰胺量-效關(guān)系的優(yōu)化 劉香梅，李培寧，劉冬虹，等(69)

自體骨膜促進(jìn)兔肩袖腱骨愈合的療效研究 趙 楊，戴海峰，劉莎莎，等(74)

微衛(wèi)星DNA標(biāo)記對(duì)BABL/c突變卷毛小鼠遺傳特性的分析 李曉娟，孫兆增，馮帆，等(80)

食蟹猴飼養(yǎng)環(huán)境氨氣及飲水中重金屬含量的分析 陸彩玲，陸繼培，黃家平，等(85)

技術(shù)方法

樹鼩糞便中沙門氏菌LAMP檢測(cè)方法建立及應(yīng)用 王璇，袁園，張志成，等(90)

實(shí)驗(yàn)動(dòng)物專家咨詢系統(tǒng)的設(shè)計(jì)與實(shí)現(xiàn) 李會(huì)萍，王曉明，劉萬(wàn)策，等(98)

研究進(jìn)展

LncRNA在心力衰竭預(yù)后判斷和治療中的潛力研究進(jìn)展 貢時(shí)雨，范慧敏，張旭敏，等(102)

腫瘤發(fā)展過程中自噬與凋亡的相互作用 闞月一，王婭杰，李琦，等(106)

乳腺癌實(shí)驗(yàn)動(dòng)物模型的研究進(jìn)展 李日飛，袁娜，冶冬陽(yáng)，等(113)

調(diào)查與觀察

廣東省實(shí)驗(yàn)動(dòng)物資源現(xiàn)狀調(diào)查及分析 林丹榮，何堅(jiān)，李文德，等(119)

標(biāo)準(zhǔn)專欄

實(shí)驗(yàn)紅鯽C1HD系遺傳質(zhì)量控制地方標(biāo)準(zhǔn)的研究 吳端生，劉娟，張朝暉(124)

專家問答

動(dòng)物模型研究中骨組織形態(tài)觀察和計(jì)量的常用方法和適用范圍 (129)

腦部微量注射給藥濃度的選擇依據(jù) (129)

第3期

研究報(bào)告

動(dòng)物行為實(shí)驗(yàn)方法學(xué)研究的回顧與展望*孫秀萍，王瓊，石哲，等(1)

大鼠獎(jiǎng)勵(lì)性條件反射實(shí)驗(yàn)中的影響因素*楊玉潔，王克柱，董黎明，等(8)

高頻電磁輻射對(duì)小鼠情緒-認(rèn)知行為的損傷作用*孫立君，高艷，郭穎，等(15)

物體認(rèn)知——基于動(dòng)物自發(fā)行為的一種學(xué)習(xí)記憶評(píng)價(jià)方法的研究*呂靜薇，宋廣青，董黎明，等(21)

先天性白內(nèi)障Rncat小鼠行為學(xué)檢測(cè)與分析*張燕，王瑩，馬嵋，等(28)

孤養(yǎng)對(duì)單次延長(zhǎng)應(yīng)激建立的創(chuàng)傷后應(yīng)激障礙模型大鼠行為學(xué)的影響 方錦穎，陳光耀，李龍梅，等(32)

研究報(bào)告

聚羥基脂肪酸和聚乳酸膜在兔青光眼濾過手術(shù)和角膜層間移植手術(shù)中的探索應(yīng)用 周吉超，戴婉薇，張紹丹，等(36)

慢性胃腸黏膜損傷樹鼩模型建立的探索 葉尤松，高家紅，趙汝，等(43)

親和吸附材料特異性清除外源性內(nèi)毒素有效性的研究 向勇平，崔輝，劉理金，等(48)

瑞舒伐他汀對(duì)膠質(zhì)瘤U87細(xì)胞遷移、侵襲的抑制作用 劉明，劉熙鵬(52)

滅活仙臺(tái)病毒體內(nèi)外誘導(dǎo)順鉑耐藥性肺腺癌A549/DDP細(xì)胞凋亡 陳則東，沈曉鵬，穆洪云，等(57)

Brown-Norway大鼠咳嗽變異性哮喘模型的建立 楚慧倫，孔德明，丁子桐，等(63)

不同周齡、性別對(duì)SJ5-SPF雞主要臟器系數(shù)、腸道長(zhǎng)度和體尺的影響 趙麗麗，韓凌霞，于海波，等(67)

技術(shù)方法

樹鼩腺病毒TaqMan實(shí)時(shí)熒光定量PCR檢測(cè)方法的建立及初步應(yīng)用 宋慶凱，李曉飛，苗雨潤(rùn)，等(72)

B超引導(dǎo)下獼猴肝臟及腎臟組織的活體穿刺方法 李哲麗，葉尤松，張庶，等(78)

微量采血法較常規(guī)采血法的技術(shù)與優(yōu)勢(shì) 吳筱琴，鐘聲，孫鍇，等(84)

經(jīng)驗(yàn)交流

樹鼩尾靜脈注射單人操作方法與經(jīng)驗(yàn) 何永旺，李娟，黃儉，等(91)

逆神經(jīng)走行方向探尋并摘取大鼠背根神經(jīng)節(jié)的改進(jìn)方法 馬理元，姜?jiǎng)磐?，張倫廣，等(95)

研究進(jìn)展

近紅外熒光(NIRF)染料在腫瘤診斷中的應(yīng)用 趙勇，王浩，師長(zhǎng)宏(98)

抗DNA病毒信號(hào)通路cGAS-STING的研究進(jìn)展 歐陽(yáng)婷，劉曉慧，任林柱(103)

急性心肌梗死后血管新生相關(guān)分子機(jī)制的研究進(jìn)展 崔加敏，劉婷婷，孫芳玲，等(108)

輔助生殖技術(shù)對(duì)小鼠表型影響的研究進(jìn)展 胡永艷，孔申申(114)

專家問答

如何構(gòu)建小鼠肥胖相關(guān)性腎病模型 (27)

肥胖相關(guān)性腎病模型的評(píng)價(jià)指標(biāo)有哪些 (113)

*“動(dòng)物行為學(xué)實(shí)驗(yàn)方法”專題

第4期

研究報(bào)告

FKBP51參與高脂誘導(dǎo)的線粒體損傷 劉明，邱彬，王婷婷，等(1)

6種光學(xué)透明化方法在大鼠腦組織塊的透明效果比較 歐毅超，馮展鵬，武廣森，等(7)

心房鈉尿肽對(duì)基因敲除小鼠移植黑色素瘤生長(zhǎng)的抑制作用 亓翠玲，曹靜樺，何亞軍，等(15)

膠原誘導(dǎo)Wistar和Lewis大鼠類風(fēng)濕關(guān)節(jié)炎模型病理特點(diǎn)的比較 施佳君，陳方明，馬全鑫，等(19)

二烯丙基二硫?qū)π∈笊?xì)胞的輻射防護(hù)作用 許帥 ，李細(xì)霞，王敏，等(27)

BALB/c小鼠全子宮切除模型的建立及機(jī)制探討 常鵬環(huán)，楊澤妹，林鈴，等(33)

系統(tǒng)性紅斑狼瘡MRL/lpr小鼠的免疫作用機(jī)制 鄺少松，楊林，嚴(yán)家榮，等(38)

一種大小鼠明暗箱圖像分析處理系統(tǒng)的研制 張宏霞，呂靜薇，張北月，等(43)

阻斷巨噬細(xì)胞介導(dǎo)的PD1/PD-L1通路對(duì)小鼠結(jié)核復(fù)發(fā)的抑制作用 孫萌萌, 秦川，唐軍，等(50)

皮質(zhì)酮誘導(dǎo)小鼠抑郁伴發(fā)的學(xué)習(xí)記憶損傷 范琳犀，楊玉潔，姜寧，等(59)

不同年齡段雌性Wistar大鼠不同骨骼區(qū)域骨密度值的測(cè)定與比較 葉尤松，王陳蕓，李哲麗，等(65)

廣州地區(qū)藏雞血液生理和生化指標(biāo)測(cè)定分析 袁進(jìn)，吳清洪，徐名襯，等(69)

姜黃素在大鼠創(chuàng)傷性腦損傷模型中的抗氧化應(yīng)激作用 梁嵐，韋會(huì)平，孫妍，等(73)

巴馬小型豬胚胎-胎仔發(fā)育毒性試驗(yàn)基礎(chǔ)數(shù)據(jù)的建立 張?jiān)?，郝新彥，高?81)

干擾E2F3基因?qū)η傲邢侔┘?xì)胞侵襲、遷移的影響 蔣昱楓，張煒，李航，等(88)

miR-126對(duì)結(jié)腸癌SW480細(xì)胞增殖、凋亡、周期及SOX2表達(dá)的影響 孟瑋，宗治國(guó)，史曉宇，等(93)

三種小鼠RNA病毒樣品儲(chǔ)運(yùn)條件對(duì)核酸檢測(cè)的影響 李欣悅，佟巍，張麗芳，等(98)

六年實(shí)驗(yàn)動(dòng)物病原菌檢測(cè)能力驗(yàn)證結(jié)果分析 邢進(jìn)，馮育芳，王洪，等(103)

技術(shù)方法

體外染色體畸變?cè)囼?yàn)染色體標(biāo)本制備的質(zhì)量控制 賈慶文，英永，馬會(huì)，等(108)

SD 大鼠腦脊液采集方法的改進(jìn) 朱奕昕，葉冬青，李曉莉(113)

研究進(jìn)展

組蛋白去乙酰酶2的結(jié)構(gòu)及其在疾病中的作用 孫欣，趙德明，楊利峰，等(116)

小膠質(zhì)細(xì)胞在神經(jīng)發(fā)育和神經(jīng)退行性疾病中的吞噬作用與調(diào)節(jié)機(jī)制 李晶文，張麗，張連峰(120)

ciRS-7在心血管類疾病中的研究進(jìn)展 羅文浩，張培東(127)

專家問答

大小鼠常見采血方法 (58)

實(shí)驗(yàn)動(dòng)物組織電鏡取材注意事項(xiàng)及要求 (87)

第5期

專題研究

多參數(shù)高場(chǎng)強(qiáng)磁共振成像評(píng)估恒河猴急性腦梗死血栓-溶栓模型*張默，吳迪，何小奪，等(01)

杏仁核快速電點(diǎn)燃癲癇大鼠神經(jīng)元限制性沉默因子表達(dá)變化*呼奶英，于佳田，別會(huì)杰，等(06)

3D細(xì)胞培養(yǎng)在阿爾茨海默病研究中的應(yīng)用*康美美，王蓉(12)

血管內(nèi)介入方法制備非人靈長(zhǎng)類動(dòng)物局部腦缺血模型的研究進(jìn)展*吳迪，何小奪，陳健，等(16)

帕金森疾病動(dòng)物模型的研究進(jìn)展*張志成，袁圓，王璇，等(21)

研究報(bào)告

表皮生長(zhǎng)因子受體抑制劑致相關(guān)皮膚瘙癢的機(jī)制研究 彭艷梅，劉青，鄧博，等(28)

三種膠原纖維染色法評(píng)價(jià)宮腔粘連的比較 陳醒，毛樂樂，周應(yīng)芳，等(34)

β-tubulin在腎臟D5R與CCKBR相互調(diào)節(jié)中的重要作用 劉星，劉云鵬，付慧，等(39)

Sestrin2在吸煙誘導(dǎo)的肺泡Ⅱ型上皮細(xì)胞損傷中的作用機(jī)制 姜曉亮，劉雪，劉云鵬，等(46)

PSGL-1通過炎癥反應(yīng)在小鼠鹽敏感性高血壓中的作用機(jī)制研究 付慧，毛紅亞，姜曉亮，等(53)

小檗堿對(duì)H2O2損傷大鼠神經(jīng)干細(xì)胞增殖的影響 孫勝男，劉欣，佟苗苗，等(60)

氯硝柳胺乙醇胺鹽對(duì)大鼠冠狀動(dòng)脈的舒張作用及機(jī)制研究 宋奇穎，郭鵬美，董麗娜，等(65)

30只普通綿耳狨猴血液學(xué)和血清生化指標(biāo)的測(cè)定及分析 滕永康，叢日旭，劉云波(70)

SIV感染猴外周血CD14+單核細(xì)胞CD169分子表達(dá)的變化 李想，薛婧，陳霆，等(75)

何首烏致大鼠腎損傷及對(duì)腎細(xì)胞凋亡的調(diào)控作用 李賀芝，段思明，王茜，等(81)

正清風(fēng)痛寧對(duì)骨關(guān)節(jié)炎動(dòng)物模型ADAMTs-4、ADAMTs-5表達(dá)的影響 陳志軍，張大華(88)

小型豬頭頸部動(dòng)脈血管的解剖結(jié)構(gòu)與三維建模 蘇卓經(jīng)，黃海龍(95)

技術(shù)方法

樹鼩副粘病毒(TPMV)PCR方法的建立及初步應(yīng)用 王淑菁，付瑞，李曉波，等(100)

經(jīng)驗(yàn)交流

C57BL/6小鼠尾靜脈四種穿刺方法的比較 溫軍業(yè)，范曉燕，何東偉，等(105)

研究進(jìn)展

中國(guó)地鼠資源開發(fā)利用的研究進(jìn)展 常凱，高繼萍，劉茂林，等(109)

基于樹突狀細(xì)胞激活建立皮膚致敏的體外方法 陳健，柯逸暉，陳彧，等(114)

繼續(xù)教育

實(shí)驗(yàn)動(dòng)物從業(yè)人員培訓(xùn)系統(tǒng)的建立與應(yīng)用 林凱麗，劉梅軒，孫井江，等(119)

專家問答

單細(xì)胞測(cè)序技術(shù)在腫瘤醫(yī)學(xué)研究中的作用 (20)

基因治療在醫(yī)學(xué)中的應(yīng)用 (52)

*“神經(jīng)系統(tǒng)疾病模型和臨床應(yīng)用”專題

第6期

研究報(bào)告

心房鈉尿肽在基因敲除小鼠黑色素瘤肺轉(zhuǎn)移中的作用 亓翠玲,曹靜樺,何亞軍,等(1)

A型肉毒素重鏈干預(yù)神經(jīng)細(xì)胞組蛋白3乙?；降某醪窖芯?蘭婧,劉福,高揚(yáng),等(4)

單增李斯特菌感染TNF-α人源化小鼠模型的建立與應(yīng)用 唐軍,孫萌萌,徐艷峰,等(10)

實(shí)驗(yàn)用狨猴微衛(wèi)星引物篩選及遺傳多樣性分析 滕永康,劉先菊,張旭,等(15)

金線蓮醇提物在斑馬魚中降血糖效果的探究 許璟瑾,張文娟,陳志永,等(21)

左卡尼汀聯(lián)合EPO和鐵劑治療大鼠腎性貧血 張風(fēng)賓,趙飛,王英南,等(29)

烏梅噴霧劑與灌胃劑對(duì)大鼠放射性口干癥治療比較研究 葉景云,陳佩儀(34)

VEGF調(diào)控Wnt/β-catenin信號(hào)通路對(duì)少突膠質(zhì)前體細(xì)胞增殖遷移的影響 孟祥武,陳娟,黃淼,等(40)

消癌平注射液對(duì)原發(fā)性肝癌模型大鼠病理形態(tài)和肝癌細(xì)胞遷移的影響及其作用機(jī)制 溫麗娜,郭楊志,仝永娟,等(46)

甘草酸對(duì)癲癇大鼠海馬神經(jīng)元損傷的保護(hù)作用及其機(jī)制 魏強(qiáng),程潔,胡玉敬,等(53)

不同周齡雌雄SJ5-SPF雞生理常數(shù)及血液生化指標(biāo)的測(cè)定與分析 趙麗麗,文輝強(qiáng),韓凌霞,等(59)

Galectin家族成員對(duì)HIV-1感染巨噬細(xì)胞凋亡的影響 王永芳,彭卓穎,李想,等(65)

TGF-β1對(duì)M2型巨噬細(xì)胞誘導(dǎo)淋巴瘤細(xì)胞增殖的影響 謝瑜,黎承平,武坤,等(72)

注射用骨肽對(duì)去卵巢骨質(zhì)疏松大鼠骨微結(jié)構(gòu)、骨密度和骨生物力學(xué)性能的影響 韓龍,吳水培(79)

柏子仁甙對(duì)阿爾茨海默病模型大鼠的行為改善作用及其相關(guān)作用機(jī)制 索金紅,牟海軍,劉曉娟,等(84)

技術(shù)方法

不同麻醉方法在大鼠腦室置管術(shù)中的效果及其對(duì)存活率的影響 楊亞南,舒晴,陳麗,等(89)

鵪鶉不同采血方法對(duì)比與評(píng)價(jià) 李高璽,林志健,張冰,等(96)

兔抗狨猴IgG-HRP標(biāo)記抗體的制備及初步鑒定 叢日旭,劉先菊,滕永康,等(101)

背入式腹膜后雙腎蒂夾閉制作腎缺血再灌注損傷模型的技術(shù)方法 謝敏慧,谷翠芝,李鳳霞,等(106)

研究進(jìn)展

口腔癌動(dòng)物模型研究進(jìn)展 續(xù)國(guó)強(qiáng),衛(wèi)佳寧,宋國(guó)華(111)

樹鼩應(yīng)用于病毒感染性疾病動(dòng)物模型的研究進(jìn)展 周風(fēng)梅,李潤(rùn)峰,袁兵,等(115)

HIV潛伏庫(kù)治療策略研究 童玲,薛婧,魏強(qiáng)(121)

細(xì)胞與生物材料聯(lián)合治療脊髓損傷的研究現(xiàn)狀 唐璽和,范益民,藍(lán)勝勇(127)

專家問答

胚胎干細(xì)胞在培養(yǎng)過程中操作注意事項(xiàng) (9)

干細(xì)胞治療在醫(yī)學(xué)研究中的應(yīng)用及其優(yōu)點(diǎn) (14)

第7期

研究報(bào)告

經(jīng)導(dǎo)管局部灌注紫杉醇模擬藥物涂層球囊預(yù)防小型豬髂總靜脈狹窄的實(shí)驗(yàn)研究 魯景元，徐文健，施萬(wàn)印，等(1)

SIVmac239病毒感染CEMx174細(xì)胞過程分析 李想，童玲，叢喆，等(7)

慢性束縛應(yīng)激聯(lián)合特殊飲食制備腹瀉性腸易激綜合征(IBS-D)大鼠模型的研究 馬曉玲，夏提古麗·阿不利孜，石磊嶺，等(12)

藁本內(nèi)酯上調(diào)miR-181b減輕氧化低密度脂蛋白誘導(dǎo)人臍靜脈內(nèi)皮細(xì)胞炎癥損傷 黃志勇，田廣永，曹玲，等(18)

七氟醚對(duì)新生大鼠神經(jīng)干細(xì)胞的增殖作用 黃劍峰，冼海燕，侯小瓊(24)

局部腦缺血再灌注損傷對(duì)小鼠TMEM166基因和神經(jīng)細(xì)胞自噬的影響 王瑜，王天龍，趙磊，等(28)

妊娠小鼠子宮內(nèi)胎鼠腹腔注射人腫瘤HepG2細(xì)胞對(duì)胎鼠生長(zhǎng)發(fā)育的影響 李?yuàn)檴?，舒昀，陳?lái)，等(33)

尾靜脈注射HL60、HL60/ADR細(xì)胞建立SCID beige小鼠白血病動(dòng)物模型的研究 張坤，徐昊淼，程涓，等(43)

營(yíng)養(yǎng)元素和蛋白聯(lián)合干預(yù)氟中毒對(duì)雌鼠卵巢功能作用 王飛清，夏曙華，鄒文兵，等(52)

蘆根多糖對(duì)高脂血癥大鼠的調(diào)節(jié)作用 陳志盛，陳景楊，張鵬寅，等(58)

慢性鋁中毒小鼠學(xué)習(xí)記憶與大腦皮層ACh、β-EP、SOD及MDA關(guān)系的研究 莫頌軼，張麗鳳，黃彥峰，等(63)

澤瀉提取物對(duì)大鼠非酒精性脂肪肝的治療作用 龔杰，丁巖，干仲元，等(68)

聯(lián)合檢測(cè)結(jié)直腸癌中GLUT-1、HIF-1α表達(dá)的臨床意義 武雪亮，王立坤，周海豐，等(77)

技術(shù)方法

新生樹鼩多巴胺神經(jīng)元的體外培養(yǎng) 李娟，曾曉鋒，楊根夢(mèng)，等(82)

獼猴脊髓損傷研究長(zhǎng)時(shí)程麻醉方案的建立及評(píng)價(jià) 馬小翠，唐濤，劉少君(87)

研究進(jìn)展

酸性調(diào)寧蛋白的研究進(jìn)展 雷蕾，刀慶，牛成慧，等(92)

哺乳動(dòng)物雙極細(xì)胞生理構(gòu)造及功能比較研究進(jìn)展 張馳，胡敏，孫曉梅，等(97)

基于復(fù)合因素誘導(dǎo)功能性消化不良大鼠模型的研究評(píng)述 龍濤，郭保君，趙映，等(102)

狨猴人工輔助生殖技術(shù)及基因修飾模型研究進(jìn)展 滕永康，劉云波(107)

SREBPs在調(diào)節(jié)骨關(guān)節(jié)炎關(guān)節(jié)軟骨退變中的作用機(jī)制研究進(jìn)展 楊占東，于紅燕，高吉俊，等(113)

星空現(xiàn)象在腫瘤中的病理意義 趙文杰，秦川(118)

靈長(zhǎng)類巨細(xì)胞病毒慢性潛伏再激活誘導(dǎo)免疫衰老的研究進(jìn)展 王宇虹，曲光瑾，肖沖，等(124)

海外漫步

第65屆日本實(shí)驗(yàn)動(dòng)物學(xué)會(huì)年會(huì)參會(huì)及考察活動(dòng) (51)

聚焦基礎(chǔ)研究，關(guān)注科研前沿 (91)

專家問答

常用的基因修飾大小鼠有哪幾大類，構(gòu)建的方法如何 (123)

用BAC克隆技術(shù)構(gòu)建轉(zhuǎn)基因小鼠的注意要點(diǎn)有哪些 (128)

第8期

專題

實(shí)驗(yàn)動(dòng)物設(shè)施的職業(yè)健康管理體系的建立與實(shí)施初探*邵奇鳴，竇木林(1)

實(shí)驗(yàn)動(dòng)物從業(yè)人員環(huán)境健康安全管理體系中生物安全培訓(xùn)的重要性*宋志剛，劉芳，任曉楠，等(7)

化學(xué)消毒劑在實(shí)驗(yàn)動(dòng)物設(shè)施中的應(yīng)用及職業(yè)健康防護(hù)*李超，張惠，梁洋洋，等(11)

使用動(dòng)物墊料添加機(jī)或墊料傾倒機(jī)時(shí)人員呼吸防護(hù)用品的評(píng)估*王昌耀，錢丹萍，孔慶學(xué)，等(16)

一種實(shí)驗(yàn)動(dòng)物設(shè)施廢氣處理裝置的研制和初步應(yīng)用*劉毅，岳慧娟，劉佳，等(21)

研究報(bào)告

京尼平對(duì)ob/ob小鼠肝部分切除術(shù)后肝再生的影響 畢楊輝，崔曉萌，於海天，等(26)

聚吡咯/聚乳酸生物材料聯(lián)合骨髓基質(zhì)細(xì)胞移植治療脊髓損傷的基礎(chǔ)研究 Raynald，舒兵，黃華，等(32)

三種小鼠腸道病毒核酸檢測(cè)技術(shù)在小鼠健康監(jiān)測(cè)中的應(yīng)用 李欣悅，佟巍，叢日旭，等(38)

雪貂微衛(wèi)星DNA遺傳多樣性分析 劉先菊，滕永康，叢日旭，等(43)

辛伐他汀PLGA緩釋微球?qū)Υ笫笞甸g盤退變的影響 陳濤，奚菊群，劉忠軍，等(49)

金黃色葡萄球菌致急性與慢性輸卵管炎性不孕癥大鼠模型的建立 胡喜姣，林春盛，李碩熙，等(56)

CRISPR/Cas9介導(dǎo)的小鼠BRCA1/BRCA2/CDH1基因乳腺特異性修飾研究 陳茜，向熙，楊漫漫，等(62)

腎復(fù)康Ⅵ號(hào)方對(duì)阿霉素腎病大鼠模型腎小球電荷屏障的影響 曹歡，劉芳，白曉紅，等(70)

四種開竅藥對(duì)急性不完全性腦缺血再灌注損傷模型大鼠的腦保護(hù)作用 黃麗，朱彩霞，張芹欣，等(77)

小兒熱速清糖漿抗流感病毒和抗菌作用研究 王敏，陳榮昌，季宇彬，等(83)

瑰及乳膏對(duì)大鼠III期壓瘡模型纖維結(jié)合蛋白及堿性成纖維細(xì)胞生長(zhǎng)因子的影響 戢艷瓊，郭俐宏，李梓香，等(90)

miR-206過表達(dá)靶向VEGFA對(duì)人肝癌HepG2細(xì)胞侵襲和遷移的抑制作用 王小明，余珊，趙曉姬(95)

技術(shù)方法

一種快速獲得Vav1基因敲除穩(wěn)定細(xì)胞系的方法 郭果，李賽超，王麗，等(101)

改良新西蘭兔頸總動(dòng)脈置管固定方法 喬少林，齊曉林，王前進(jìn)，等(108)

ABSL-2實(shí)驗(yàn)室相對(duì)濕度波動(dòng)原因的分析與對(duì)策 谷鑫，呂陽(yáng)，盧選成，等(112)

研究進(jìn)展

延長(zhǎng)溶栓時(shí)間窗在缺血性腦卒中tPA治療的臨床前研究進(jìn)展 陶依然，劉婷婷，孫芳玲，等(118)

長(zhǎng)鏈非編碼RNA MIAT與腫瘤關(guān)系的研究進(jìn)展 孫程，黃立寧，李景林，等(124)

NLRP3炎癥小體在肝疾病中的作用 孔德龍，崔潔(129)

Pig-a基因突變?cè)囼?yàn)研究進(jìn)展 鄭丹丹，秦美蓉，王曉煒，等(135)

快訊

AnimalModelsandExperimentalMedicine被國(guó)際數(shù)據(jù)庫(kù)DOAJ收錄 (141)

第十四屆中國(guó)實(shí)驗(yàn)動(dòng)物科學(xué)年會(huì)通知 (141)

*“職業(yè)健康在實(shí)驗(yàn)動(dòng)物科學(xué)研究中的作用”專題

第9期

研究報(bào)告

咪喹莫特對(duì)BALB/c和C57BL/6小鼠銀屑病樣皮損誘導(dǎo)作用的比較 吳劍平，謝倩，陳林，等(01)

樹鼩大腸內(nèi)容物細(xì)菌的群落多樣性分析 郭玉倩，角建林，袁鑫，等(07)

長(zhǎng)爪沙鼠糖尿病近交系培育過程中血液生理生化指標(biāo)的動(dòng)態(tài)變化 王迎，李迎，王東平，等(14)

五指山小型豬PPARγ2基因啟動(dòng)子多態(tài)性分析 潘金春，閔凡貴，王希龍(21)

復(fù)方阿膠漿對(duì)小鼠子宮內(nèi)膜作用研究 丁桂清，魏華芳，王立群，等(27)

多囊卵巢綜合征大鼠卵巢顆粒細(xì)胞中DR5、DcR2的表達(dá)變化 張娟，王立群，周月希，等(33)

樹鼩膽石模型與消化道P物質(zhì)相關(guān)的研究 呂龍寶，陳麗雄，王俊斌，等(40)

建立高尿酸血癥性腎損害小鼠模型的實(shí)驗(yàn)研究 裴憶雪，劉永杰，張笛，等(46)

基于肝門靜脈注射腫瘤細(xì)胞的新型進(jìn)展期肝臟腫瘤動(dòng)物模型的建立 柴燕濤，姜棋予，馮帆，等(55)

沉默Blimp-1促進(jìn)IFN-γ表達(dá)抑制肝癌細(xì)胞的作用研究 鄧浩，彭啟旺，李偉(61)

周齡對(duì)非肥胖型糖尿病背景小鼠體外受精效果的影響 閻濤，胡萍，徐晨，等(66)

技術(shù)方法

“互聯(lián)網(wǎng)+”實(shí)驗(yàn)動(dòng)物資源共享服務(wù)平臺(tái)模式研究 李會(huì)萍，王曉明，楊錦淳，等(69)

經(jīng)驗(yàn)交流

四種常用實(shí)驗(yàn)動(dòng)物與人的肝組織形態(tài)特征比較 李靖，王艷麗，劉恩岐(74)

品管圈在降低動(dòng)物實(shí)驗(yàn)不規(guī)范行為發(fā)生率中的應(yīng)用 梁磊，尤金煒，胡文娟，等(78)

設(shè)施設(shè)備

動(dòng)物鼻式氣溶膠暴露裝置的運(yùn)行效果評(píng)價(jià) 郝新彥，向志光，高虹(83)

生物安全型禽負(fù)壓隔離器的研制 張宗興，祁建城，吳金輝，等(90)

研究進(jìn)展

環(huán)狀非編碼RNA在口腔鱗癌中的研究進(jìn)展 衛(wèi)佳寧，續(xù)國(guó)強(qiáng)，高繼萍，等(96)

情緒異常大鼠模型的曠場(chǎng)行為實(shí)驗(yàn)在中醫(yī)藥領(lǐng)域的研究進(jìn)展 張鵬橫，阮璐薇，卓澤偉，等(100)

樹鼩在人類代謝性疾病中的應(yīng)用與展望 夏巍，賴永靜，杜龍，等(104)

成纖維細(xì)胞向運(yùn)動(dòng)神經(jīng)元的分化研究進(jìn)展 施玉婷，李峰(110)

大鼠星狀神經(jīng)節(jié)阻滯方法的綜述 胡可，張炳東(115)

調(diào)查報(bào)告

抗菌藥物合理使用對(duì)臨床手術(shù)感染率影響的比較醫(yī)學(xué)分析 黃小燕，趙喜榮，曹瑞麗(120)

快訊

AnimalModelsandExperimentalMedicine被國(guó)際數(shù)據(jù)庫(kù)DOAJ收錄 (60)

第十四屆中國(guó)實(shí)驗(yàn)動(dòng)物科學(xué)年會(huì)通知 (109)

第10期

研究報(bào)告

RNA-Seq技術(shù)篩選APP/PS1阿爾茨海默病模型小鼠差異表達(dá)基因及功能分析 史長(zhǎng)華，張玲，陳巍，等(1)

斑馬魚mcm5基因的表達(dá)分析及在體節(jié)發(fā)生中的功能 張雨，吳永梅，劉敏，等(8)

腎結(jié)石兩種造模方式血、尿生化的動(dòng)態(tài)比對(duì)研究 郝志強(qiáng)，王勤章，倪釗，等(15)

生理性衰老小鼠的感染免疫模型建立 袁松華，傅衛(wèi)輝，何涌泉，等(20)

束縛和異氟烷麻醉對(duì)大鼠心率變異性及HPA軸影響的比較 王曉宇，何偉，馬富強(qiáng)，等(28)

正常巴馬小型豬與高血糖家系F 5代血液生理生化指標(biāo)比較研究 鄧俊成，蘇小華，呂明，等(36)

清熱化痰解毒方對(duì)卒中相關(guān)性肺炎大鼠Akt/JNK3/Caspase-3和NF-κB信號(hào)通路的影響 王濤，劉宏祥，王穎，等(42)

淫羊藿苷對(duì)SCID小鼠前列腺癌原位移植瘤雄激素受體信號(hào)通路的影響 陳德森，胡熙耀，陳少秀，等(49)

microRNA- 494通過TLR- 4通路抑制成骨細(xì)胞分化及基質(zhì)礦化的分子機(jī)制 匡嘉兵，徐昊，張克良，等(55)

兩品系大鼠經(jīng)皮電阻試驗(yàn)結(jié)果的比較*羅飛亞，馮克然，張露勇，等(61)

鐵皮石斛多糖對(duì)慢性萎縮性胃炎大鼠的作用及其分子機(jī)制研究 歐陽(yáng)一鳴，凌平，李臨海，等(67)

幼羊顱骨缺損模型中顱骨組織Dlx2基因的表達(dá)及意義分析 畢玉杰，周昊，崔陽(yáng)，等(73)

人類表皮細(xì)胞衰老相關(guān)的microRNA差異性表達(dá)與信號(hào)通路分析 韓銀淑(79)

技術(shù)方法

開設(shè)藥理學(xué)非成癮性鎮(zhèn)痛藥實(shí)驗(yàn)教學(xué)項(xiàng)目的探索 劉芬，關(guān)鳳英，張大威，等(85)

實(shí)驗(yàn)大鼠和小鼠多種細(xì)菌PCR檢測(cè)與分析 馮潔，謝建云，魏曉鋒，等(89)

教學(xué)管理

加強(qiáng)醫(yī)學(xué)研究生實(shí)驗(yàn)動(dòng)物福利教育的思考*鞠吉雨，徐玉梅，耿云峰，等(94)

設(shè)施設(shè)備

一種新型干養(yǎng)式兔籠架具的特點(diǎn)分析 鄒巖柏，梁春南，趙明海，等(98)

研究進(jìn)展

FKBP1B基因?qū)π哪X血管系統(tǒng)作用的研究進(jìn)展 高一，呂陽(yáng)，劉理想，等(106)

多重PCR技術(shù)在實(shí)驗(yàn)動(dòng)物病原檢測(cè)中的應(yīng)用 張飛燕，趙玲，金潔，等(111)

色氨酸2，3-雙加氧酶在中樞神經(jīng)系統(tǒng)疾病中的作用及其治療策略思考 傅曉鳳，洪璐威，王鈺婷，等(117)

體育科學(xué)研究中實(shí)驗(yàn)動(dòng)物“3R”原則的應(yīng)用及進(jìn)展*左群，于新凱(122)

實(shí)驗(yàn)動(dòng)物的安樂死及其實(shí)施方法的倫理分析*李楠，王天奇，何嘉玲，等(128)

實(shí)驗(yàn)動(dòng)物福利倫理審查的標(biāo)準(zhǔn)化與我國(guó)新國(guó)標(biāo)解讀*孫德明，李蔚鷗，王天奇，等(133)

會(huì)訊

《中國(guó)實(shí)驗(yàn)動(dòng)物學(xué)報(bào)》《中國(guó)比較醫(yī)學(xué)雜志》第四屆編委會(huì)換屆大會(huì)隆重召開 (35)

*“實(shí)驗(yàn)動(dòng)物福利和倫理審查”專題

第11期

研究報(bào)告

1,25(OH)2VD3對(duì)Zucker糖尿病肥胖大鼠肝線粒體損傷的保護(hù)作用 李艷艷，馮里茹，張紅敏，等(01)

大黃素對(duì)ApoE基因敲除小鼠脂肪棕色化的影響 程龍，董世芬，袁悅瑩，等(08)

miR-34c在口腔鱗狀細(xì)胞癌的表達(dá)及對(duì)Tca8113細(xì)胞生物學(xué)行為的影響 常凱，高繼萍，宋曉娜，等(15)

4T1炎性乳腺癌細(xì)胞接種聯(lián)合皮質(zhì)酮注射誘導(dǎo)乳腺癌并發(fā)抑郁癥小鼠模型的研究 楊蕙，孟盼，楊琴，等(21)

自發(fā)性2型糖尿病db/db小鼠肝病理?yè)p傷特點(diǎn) 康佳麗，梁偉時(shí)，孟徐兵，等(27)

膠原誘導(dǎo)與抗原誘導(dǎo)C57BL/6小鼠類風(fēng)濕關(guān)節(jié)炎造模的比較研究 范凱健，吳菁，王婷玉(31)

用于四種常用品系大鼠鑒定的單核苷酸多態(tài)性標(biāo)記篩查和應(yīng)用研究 曾玉琳，蒙裕歡，張鈺，等(36)

醒腦再造膠囊對(duì)甲醛致小鼠記憶損害的影響 盛志豪，陳穎，馬瑞，等(42)

姜黃素預(yù)處理對(duì)干熱環(huán)境下不同程度中暑大鼠病理?yè)p傷及氧化應(yīng)激的影響 李建瑛，肇寅輝，康燕，等(48)

肺腺瘤小鼠模型的建立及其血生化、血常規(guī)、尿常規(guī)、病理檢測(cè) 張修彥，高亞奇，陳偉盛，等(53)

廣州馴化藏雞與五黑雞蛋品質(zhì)及營(yíng)養(yǎng)成分比較分析 袁進(jìn)，吳清洪，陳傍柱，等(60)

GnRH-a反加雌激素對(duì)大鼠子宮內(nèi)膜異位癥模型的療效及復(fù)發(fā)的研究 張玲玉，劉穎蕾，喬海風(fēng)，等(67)

裸鼠原位肝癌動(dòng)態(tài)影像檢查與病理對(duì)照研究 沈智勇，陳瑜鳳，邵晶晶，等(74)

三個(gè)遠(yuǎn)交系豚鼠微衛(wèi)星遺傳結(jié)構(gòu)分析 劉迪文，譚海明，陳雁虹，等(81)

GFP/Luc雙標(biāo)食管癌細(xì)胞動(dòng)物模型建立及其活體成像觀察 柏文，彭曉清，王佩文，等(89)

梔子苷對(duì)乳腺炎動(dòng)物模型IL-6、TNF-α和IL-1β表達(dá)的影響 黃永周，李漪，叢竹軍(95)

技術(shù)方法

SD大鼠肢體缺血-再灌注損傷模型的建立 申震，朱付平，潘成熙，等(100)

應(yīng)用新型超聲診斷儀檢測(cè)大鼠心功能 陳婷婷，廖獻(xiàn)杉，曾蘭，等(106)

教學(xué)管理

“雙一流”模式下高校研究生實(shí)驗(yàn)動(dòng)物學(xué)課程教學(xué)模式探索 吳艷玲，張先，崔振宇，等(111)

醫(yī)學(xué)生實(shí)驗(yàn)動(dòng)物福利與倫理實(shí)踐教學(xué)的思考 高建峰，湯宏斌，楊四軍，等(115)

基于成果導(dǎo)向教育理念的實(shí)驗(yàn)動(dòng)物科研項(xiàng)目在大學(xué)生綜合素質(zhì)培養(yǎng)中的實(shí)踐 鞠吉雨，徐玉梅，劉琳琳，等(119)

中醫(yī)院校本科生階段開設(shè)“實(shí)驗(yàn)動(dòng)物學(xué)”選修課的探索 劉建衛(wèi)，章明星，潘建明，等(123)

會(huì)訊

《中國(guó)實(shí)驗(yàn)動(dòng)物學(xué)報(bào)》《中國(guó)比較醫(yī)學(xué)雜志》第四屆編委會(huì)換屆大會(huì)隆重召開 (66)

第12期

研究報(bào)告

炎癥因子風(fēng)暴對(duì)老年小鼠感染免疫應(yīng)答的影響 袁松華，何涌泉，徐建青，等(1)

氨基葡萄糖鹽酸鹽及其衍生物對(duì)斑馬魚骨骼損傷修復(fù)的比較研究 張文娟，許璟瑾，姚麗云，等(9)

姜黃素預(yù)處理對(duì)干熱環(huán)境熱射病大鼠心肌氧化應(yīng)激及細(xì)胞凋亡的影響 馬娜，李佳佳，宋來(lái)陽(yáng)，等(14)

薄型子宮內(nèi)膜小鼠模型的免疫組化鑒定與生育力評(píng)估 張汝月，李瑞嬌，張引紅，等(19)

小型豬腎臟血管的三維可視化建模及意義 鄧健全，黃海龍(27)

木犀草素對(duì)甲狀腺乳頭狀癌TPC-1細(xì)胞侵襲遷移的影響及其機(jī)制 鐘燁，王超，徐博，等(32)

Tlr4基因敲除小鼠生長(zhǎng)和繁殖的實(shí)驗(yàn)研究 鄭洋，王佳慧，劉露露，等(38)

氟西汀對(duì)卒中后抑郁模型大鼠的行為及海馬神經(jīng)元新生的影響 李愛平，田靜，周芝文，等(41)

探討干酪乳桿菌對(duì)胃癌大鼠的抗腫瘤作用及其免疫學(xué)機(jī)制研究 張丹，王允野(48)

用于實(shí)驗(yàn)用貓群體遺傳分析的微衛(wèi)星位點(diǎn)篩選 賈松華，王洪，魏杰，等(55)

低分子肝素鈣對(duì)小鼠胚胎著床的干預(yù)作用及機(jī)制研究 楊文，楊艷，吳曉燕，等(61)

人源性肝癌細(xì)胞小鼠原位移植瘤模型的建立及特點(diǎn)的比較研究 尹君，李景丁莎，左從林，等(68)

不同方法誘導(dǎo)大鼠非酒精性單純性脂肪肝模型的CYP酶活性比較研究 金毅，邢偉，呂愛貞，等(75)

基于超聲心動(dòng)圖技術(shù)評(píng)價(jià)食蟹猴急性心肌梗死模型左室結(jié)構(gòu)和功能的變化 王成舟，楊倩，張才喬(84)

技術(shù)方法

獼猴體況評(píng)價(jià)系統(tǒng)的建立和探討 張玉林，胡正飛，劉超，等(89)

大鼠陰道涂片兩種染色方法比較 張婷，王穎，王莉(98)

設(shè)施設(shè)備

實(shí)驗(yàn)動(dòng)物屏障設(shè)施系統(tǒng)自動(dòng)化控制技術(shù)體系應(yīng)用探索 李可欣，張鳳梅，楊根嶺，等(102)

研究進(jìn)展

鼻咽癌實(shí)驗(yàn)動(dòng)物模型的研究進(jìn)展 肖洋洋，卿吉琳，李寶絢，等(108)

斑馬魚:人類腎臟疾病治療藥物篩選的新工具 汪玲，陳朝紅(113)

I型遺傳性酪氨酸血癥動(dòng)物模型研究進(jìn)展 顧鵬，劉聞，袁進(jìn)，等(119)

化療相關(guān)性腹瀉動(dòng)物模型構(gòu)建的研究概述 吳夢(mèng)雨，鄧博，賈立群(124)

用于評(píng)價(jià)大小鼠學(xué)習(xí)記憶能力的迷宮實(shí)驗(yàn)方法比較 楊玉潔，李玉姣，李杉杉，等(129)

《中國(guó)比較醫(yī)學(xué)雜志》2018年總目次 (135)

《中國(guó)比較醫(yī)學(xué)雜志》稿約 (151)

CHINESEJOURNALOFCOMPARATIVEMEDICINE
INDEXOFCONTENTS
Vol.28No.1～12，2018

Issue1

Comparison of rat models of intrauterine growth retardation established by three different methodsGAOLinlin,WANGJun,LIZiying,etal.(1)

Mineral and bone metabolism disorder in an adenine-induced rat model of chronic kidney diseaseMENGYan,ZHANGHao,HENing,etal.(8)

Effects of histamine on the motor activity and spatial memory ability in depressive ratsHEYecheng,YAOJuan,CHENShang,etal.(16)

Ameliorating effect of Xionggui Liujunzi Decoction on coronary heart disease in ratsZHENGLili(23)

Neuroprotective effect of erythropoietin on rat model of hypoxic-ischemic encephalopathyDUANMiao,CAOYuntao,WANGXuqin(28)

Comparison of gender differences in the rat model of fluorosisLIUYang,HANLunying,HEChuan,etal.(33)

Establishment and evaluation of a rabbit model of premature ovarian failure induced by cyclophosphamideZHANGJuan,ZHOUYuexi,DIAOBo,etal.(38)

Comparison of hepatotoxicity and toxic mechanisms of matrine and oxymatrine usinginvivoandinvitromodelsGUOQiuping,CHENGuiying,ZHOUQuan,etal.(44)

Anatomy of caudal vessels of the rat and physiological functions of rat tailWANGLei,YEMingxia(51)

Effects of different local intervention temperatures on endoplasmic reticulum stress and cell apoptosis in pressure ulcer of ratsWANGQing,DUXiaofei,XINGFengmei,etal.(56)

Effect of tempol on NF-κB signaling pathway in the rat model of myocardial hypertrophyLIUJiandi,XIELong,XIAOKun,etal.(64)

Analysis of transcriptional levels ofCMAHin different organ tissues of miceLIYifan,YANGNa,WANGYao,etal.(70)

Effects of portal hypertension on endotoxin levels in serum and intestinal mucosa in ratsLIXiaojuan,ZHANGQiaoyun,FENGFan,etal.(76)

Effect of combined anesthesia on Wuzhishan miniature pigs in surgery lasting up to 8 hoursDUANTianbing,ZHANGJinxia,XIANGDingcheng,etal.(80)

Methodological evaluation of urinary mercury detection using Zeeman atomic absorption mercury analyzerZHOUYing,WANGYing,HUANGHai(86)

A modified suction device with negative pressure for cerebrospinal fluid collection in ratsWANGWei,LIDongbin,LUOXiumei,etal.(91)

A rapid and useful method for gender identification of grey red-backed volesMAQin,WANGYuanzhi,LUTaofeng,etal.(96)

Observation of several physiological indexes of rhesus monkeys by implantable telemetry technologyLUQijiong,CHENMinhua,XUCong,etal.(100)

Feasibility study of acupuncture treatment on the miniature pig model of chronic myocardial ischemiaZHANGJinling,TIANYi,RONGPeijing,etal.(108)

Research progress ofCYP450 genes expressed in brain involved in the metabolism of endogenous substancesYANGXinlan,LVDan,ZHANGLianfeng(113)

Characteristics and research strategies of patient-derived orthotopic xenograft modelsCHENXue,ZHANGHe,SHIChanghong(118)

P301L tau transgenic animal models and their applicationsMADenglei,ZHANGRuyi,LILin(123)

Issue 2

Effect of TRPV4 on angiotensin II-induced renal injury in miceYANFengna，LIUSuxiao，CUILin，etal.(1)

Xueshuantong capsule alleviates oxygen-glucose deprivation /reoxygenation-induced tight junction damage of HUVEC cellsYANGAiling，WUTing，ZhangTianrui，etal.(7)

Effect of botulinum neurotoxin type A heavy chain on the growth-related proteins after spinal cord injury in ratsWANGYafang，LANJing，LIUFu，etal.(12)

Effect of vitamin D deficiency on pathogenesis of Zucker diabetic fatty ratLIYanyan，WANGNing，LIUYanyan，etal.(20)

Hematopoietic stem cell injury in mice induced by busulfanLIChengcheng，GUANBowen，SULu，etal.(26)

Establishment and characterization of a rat model of hypertension with hyperlipidemiaZHAOShengnan，HELili，LIZiqiang，etal.(33)

ism1 regulates convergence and extension movements during zebrafish gastrulationWANGZheng，LIJinpeng，YANYifang，etal.(40)

Restoration of the lost B-cell phenotype in classical Hodgkin lymphoma cells by all trans-retinoic acid treatmentDUJing，GONGKaikai，YANGLijuan，etal.(46)

Effect of platelet rich plasma combined with core decompression on the repair of steroid-induced avascular necrosis of the femoral head and the MMP/TIMP in rabbitsYUPeng，JIZhihua，JIABingshen，etal.(53)

Construction and characterization of a eukaryotic expression vector of full-length and mature IL-37bLIMengyuan，WEIRongfei，YANGXingjiu，etal.(59)

Effects of Toddalia asiatica extract on inflammatory cytokines in rats with myocardial ischemia and hyperlipidemiaLIUMing，LIUYang，DENGYing，etal.(64)

Optimization of the dose-effect relationship of N-ethyl-N-nitrocarbamide and cyclophosphamide inPig-agene mutation detection in ratsLIUXiangmei，LIPeining，LIUDonghong，etal.(69)

Therapeutic effect of autologous periosteum on the healing of tendon-bone interface in rabbits rotator cuff tearZHAOYang，DAIHaifeng，LIUShasha，etal.(74)

Analysis of genetic characteristics of BABL/c mutant curly mice by microsatellite DNA markersLIXiaojuan，SUNZhaozeng，F(xiàn)ENGFan，etal.(80)

Analysis of the ammonia level in air and heavy metals in drinking water in a cynomolgus monkey feedlotLUCailing，LUJipei，HUANGJiaping，etal.(85)

Establishment and application of a loop-mediated isothermal amplification assay for the detection ofSalmonellain feces of tree shrewsWANGXuan，YUANYuan，ZHANGZhicheng，etal.(90)

Design and implementation of laboratory animal expert consultation systemLIHuiping，WANGXiaoming，LIUWance，etal.(98)

Research progress of LncRNA in prognosis and treatment of heart failureGONGShiyu，F(xiàn)ANHuimin，ZHANGXumin，etal.(102)

Interaction between autophagy and apoptosis during tumor developmentKANYueyi，WANGYajie，LIQi，etal.(106)

Research progress in experimental animal models of breast cancerLIRifei，YUANNa，YEDongyang，etal.(113)

An investigation of laboratory animal resources in Guangdong provinceLINDanrong,HEJian,LIWende，etal.(119)

Standards for genetic quality control for the laboratory red crucian Carp C1HD strainWUDuansheng，LIUJuan，ZHANGZhaohui(124)

Issue 3

Review and prospect of experiment methodology on animal behaviorSUNXiuping,WANGQiong,SHIZhe,etal.(1)

The impact factors in reward conditioned reflex test of ratsYANGYujie,WANGKezhu,DONGLiming,etal.(8)

Behavioral tests of mood-cognitive impairment of mice exposed to high-frequency electromagnetic radiationSUNLijun,GAOYan,GUOYing,etal.(15)

Object recognition test—a method to assess the learning and memory in mice based on their spontaneous behaviorLYUJingwei,SONGGuangqing,DONGLiming,etal.(21)

Measurement and analysis of the behavioral changes of Rncat congenital cataract miceZHANGYan,WANGYing,MAMei,etal.(28)

Effect of social isolation on the behavior of rat models of post-traumatic stress disorder established by single-prolonged stressFANGJinying,CHENGuangyao,LILongmei,etal.(32)

Exploration and application of polyhydroxyalkanoates and polylactic acid membranes during glaucoma filtering surgery and interlaminar transplantation in rabbitsZHOUJichao,DAIWanwei,ZHANGShaodan,etal.(36)

Exploration of establishing a tree shrew model of chronic gastrointestinal mucosal injuryYEYousong,GAOJiahong,ZHAORu,etal.(43)

Effectiveness of the specific removal of exogenous endotoxin by an affinity adsorption materialXIANGYongping,CUIHui,LIULijin,etal.(48)

Inhibitory effect of rosuvastatin on migration and invasion of U87 glioma cellsinvitroLIUMing,LIUXipeng(52)

Inactivated Sendai virus induces apoptosis in cisplatin-resistant human lung adenocarcinoma A549 cellsinvitroandinvivoCHENZedong,SHENXiaopeng,MUHongyun,etal.(57)

Establishment of a Brown-Norway rat model of cough variant asthmaCHUHuilun,KONGDeming,DINGZitong,etal.(63)

Effects of different weeks of age and sex on the main organ coefficients, intestinal length and body size of SJ5-SPF chickensZHAOLili,HANLingxia,YUHaibo,etal.(67)

Establishment and application of a TaqMan real-time fluorescence quantitative PCR for detection of tree shrew adenovirus (TAV)SONGQingkai,LIXiaofei,MIAOYurun,etal.(72)

Biopsy of liver and kidney tissues in rhesus monkeys under B-mode ultrasound guidanceLIZheli,YEYousong,ZHANGShu,etal.(78)

Technique and advantages of a blood micro-sampling method compared with regular sampling method in miceWUXiaoqin,ZHONGSheng,SUNKai,etal.(84)

A single person operation procedure and experience of tail vein injection in conscious tree shrewsHEYongwang,LIJuan,HUANGJian,etal.(91)

An improved method of exploring and extracting dorsal root ganglions in rats by reversely along the nerve traveling pathwayMALiyuan,JIANGJingting,ZHANGLunguang,etal.(95)

Application of near-infrared fluorescent dyes in tumor diagnosisZHAOYong,WANGHao,SHIChanghong(98)

Research progress of cGAS-STING signaling pathway in anti-DNA virus immunityOUYANGTing,LIUXiaohui,RENLinzhu(103)

Research progress on molecular mechanisms of angiogenesis after acute myocardial infarctionCUIJiamin,LIUTingting,SUNFangling,etal.(108)

Research progress on the effects of assisted reproductive technology on phenotypes of miceHUYongyan,KONGShenshen(114)

Issue 4

Involvement ofFKBP51 in mitochondrial damage induced by high fat diet feedingLIUMing,QIUBin,WANGTingting，etal.(1)

Comparison of transparent effects of six different optical clearing methods on rat brain tissuesOUYichao，F(xiàn)ENGZhanpeng，WUGuangsen，etal.(7)

Inhibitory effect of atrial natriuretic peptide (ANP) on the tumor growth of ANP knockout mouse and C57BL/6J mouse models of subcutaneous xenotransplanted melanomaQICuiling,CAOJinghua,HEYajun，etal.(15)

Comparison of pathological characteristics of Wistar and Lewis rat models of collagen-induced rheumatoid arthritisSHIJiajun,CHENFangming,MAQuanxin，etal.(19)

Protective effect of diallyl disulfide against the radiation damage in germ cells of male miceXUShuai，LIXixia，WANGMin，etal.(27)

Establishment and mechanism of a BALB/c mouse model of total hysterectomyCHANGPenghuan，YANGZemei，LINLing，etal.(33)

Exploration of the immune mechanism in systemic lupus erythematosus MRL/lpr miceKUANGShaosong，YANGLin，YANJiarong，etal.(38)

Development of a computer-aided-controlling and image analysis system for light/dark box test in mice and ratsZHANGHongxia，LYUJingwei，ZHANGBeiyue，etal.(43)

Blockage of macrophage-mediated PD1/PD-L1 pathways inhibits tuberculosis relapse in miceSUNMengmeng，QINChuan，TANGJun，etal.(50)

Chronic injection of corticosterone induces depression and impairment of learning and memory in miceFANLinxi,YANGYujie,JIANGNing，etal.(59)

Determination and comparison of the bone mineral density of different skeletal regions of female Wistar rats at different agesYEYousong，WANGChenyun，LIZheli，etal.(65)

Analysis and measurement of blood physiological and biochemical parameters in Tibetan chickens bred in GuangzhouYUANJin,WUQinghong,XUMingchen，etal.(69)

Anti-oxidative stress effects of curcumin on rat models of traumatic brain injuryLIANGLan，WEIHuiping，SUNYan，etal.(73)

Establishment of basic data of Bama minipigs for embryo-fetal development toxicity studyZHANGYuanhui，HAOXinyan，GAOHong(81)

Effect of E2F3 gene interfering on the invasion and migration of prostate cancer cellsJIANGYufeng，ZHANGWei，LIHang，etal.(88)

Effect of miR-126 on proliferation and apoptosis in colon cancer cells via targeting regulation of SOX2 expressionMENGWei，ZONGZhiguo，SHIXiaoyu，etal.(93)

Effects of transport and storage conditions on the nucleic acid detection for three kinds of mouse RNA viral samplesLIXinyue,TONGWei,ZHANGLifang，etal.(98)

Analysis of proficiency testing results for pathogenic bacteria in laboratory animal in six yearsXINGJin，F(xiàn)ENGYufang，WangHong，etal.(103)

Quality control of chromosome preparation in the chromosome aberration test in vitroJIAQingwen,YINGYong,MAHui，etal.(108)

An improved method of collecting cerebrospinal fluid in SD ratsZHUYixin,YEDongqing,LIXiaoli(113)

The structure of histone deacetylase 2 and its role in diseasesSUNXin,ZHAODeming,YANGLifeng，etal.(116)

Phagocytic function of microglia and underlying regulatory mechanism in neurodevelopment and neurodegenerative diseasesLIJingwen,ZHANGLi,ZHANGLianfeng(120)

Research progress of ciRS-7 in cardiovascular diseasesLUOWenhao,ZHANGPeidong(127)

Issue 5

High-field magnetic resonance imaging with multiple parameters to evaluate the thrombus-thrombolysis model in rhesus monkeys with acute cerebral infarctionZHANGMo,WUDi,HEXiaoduo,etal.(01)

Changes in expression of repressor element silencing transcription factor in rapid amygdala kindling epilepsy ratsHUNaiying,YUJiatian,BIEHuijie,etal.(06)

Application of three-dimensional cell culture in the study of Alzheimer’s diseaseKANGMeimei,WANGRong(12)

Research progress of focal ischemic stroke in nonhuman primates using endovascular methodsWUDi,HEXiaoduo,CHENJian,etal.(16)

Research progress on animal models of Parkinson’s diseaseZHANGZhicheng,YUANYuan,WANGXuan,etal.(21)

Mechanistic study of epidermal growth factor receptor inhibitor-related pruritusPENGYanmei,LIUQing,DENGBo,etal.(28)

Comparison of three special staining methods for collagen fibers in evaluation of intrauterine adhesionCHENXing,MAOLele,ZHOUYingfang,etal.(34)

Mechanistic study of β-tubulin and its interaction with the dopamine D5 receptor, cholecystokinin B receptor, and water-sodium metabolismLIUXing,LIUYunpeng,FUHui,etal.(39)

Protective effect and mechanism of Sestrin2 in the development of pulmonary alveolar type II epithelial cell injury induced by cigarette smokingJIANGXiaoliang,LIUXue,LIUYunpeng,etal.(46)

Study on the mechanism of PSGL-1 in salt-sensitive hypertension via inflammation in miceFUHui,MAOHongya,JIANGXiaoliang,etal.(53)

Proliferation effects of berberine on rat neural stem cells induced by hydrogen peroxideSUNShengnan,LIUXin,TONGMiaomiao,etal.(60)

Vasorelaxant effect and mechanism of niclosamide ethanolamine on rat coronary arterySONGQiying,GUOPengmei,DONGLina,etal.(65)

Detection and analysis of hematological and serum biochemical indices of thirty common marmosetsTENGYongkang,CONGRixu,LIUYunbo(70)

Changes in the expression of CD169 on peripheral blood CD14+monocytes of rhesus monkeys after SIV infectionLIXiang,XUEJing,CHENTing,etal.(75)

Effects ofPolygonummultiflorumon kidney injury and renal cell apoptosis in SD ratsLIHezhi,DUANSiming,WANGXi,etal.(81)

Effect of Zhengqingfengtongning on the expression of aggrecanase-1 (ADAMTs-4) and aggrecanase-2 (ADAMTs-5) in the cartilage tissue of knee joint in rabbit models of osteoarthritisCHENZhijun，ZHANGDahua(88)

CT-imaging-based anatomical and three-dimensional modeling of the head and neck arterial vessels of the miniature pigSUZhuojing,HUANGHailong(95)

Establishment and application of a PCR detection method forTupaia(tree shrew) paramyxovirus (TPMV)WANGShujing,FURui,LIXiaobo,etal.(100)

Comparison of different puncture methods in C57BL/6 mouse tail veinsWENJunye,FANXiaoyan,HEDongwei,etal.(105)

Advances in development and application of Chinese hamster resourceCHANGKai,GAOJiping,LIUMaolin,etal.(109)

Invitromethod for skin sensitization based on dendritic cell activationCHENJian,KEYihui,CHENYu,etal.(114)

Establishment and application of the training system for laboratory animal employeesLINKaili,LIUMeixuan,SUNJingjiang,etal.(119)

Issue 6

Effect of atrial natriuretic peptide (ANP) on pulmonary melanoma metastasis in ANP knockout mice and C57BL/6J miceQICuiling,CAOJinghua,HEYajun,etal.(1)

Botulinum neurotoxin serotype A heavy chain intervenes in the H3 acetylation: A preliminary studyLANJing,LIUFu,GAOYang,etal.(4)

Establishment and application of a TNF-α humanized mouse model ofListeriamonocytogenesinfectionTANGJun,SUNMengmeng,XUYanfeng,etal.(10)

Microsatellite marker design and genetic analysis for the common marmosetTENGYongkang,LIUXianju,ZHANGXu,etal.(15)

Exploration of the hypoglycemic effect of Anoectochilus roxburghii alcohol extracts on diabetic zebrafish modelsXUJingjin,ZHANGWenjuan,CHENZhiyong,etal.(21)

Therapeutic effect of L-carnitine combined with erythropoietin and iron on renal anemia in ratsZHANGFengbin,ZHAOFei,WANGYingnan,etal.(29)

Comparison of the therapeutic effects of dark plum mixture given by gastric gavage and oral spray on rats with radiation-induced xerostomiaYEJingyun,CHENPeiyi(34)

Effect of VEGF-regulated Wnt/β-catenin signaling pathway on the proliferation and migration of oligodendrocyte precursor cellsMENGXiangwu,CHENJuan,HUANGMiao,etal.(40)

Effect of a Chinese medicine Xiao Aiping injection on the primary liver cancer pathology and the cancer cell migration ability in rat models, and their mechanism of actionWENLina,GUOYangzhi,TONGYongjuan,etal.(46)

Protective effect and mechanism of glycyrrhizic acid on the hippocampal neuron injury in epileptic rat modelsWEIQiang,CHENGJie,HUYujing,etal.(53)

Determination and analysis of physiological constants and blood biochemical indexes of male and female SJ5-SPF chickens at the age of different weeksZHAOLili,WENHuiqiang,HANLingxia,etal.(59)

Effects of galectins on the apoptosis in HIV-1-infected macrophagesWANGYongfang,PENGZhuoying,LIXiang,etal.(65)

Effect of TGF-β1 on the proliferation of lymphoma cells induced by M2 macrophagesXIEYu,LIChengping,WUKun,etal.(72)

Effects of ossotide injection on bone mineral density (BMD), bone microstructure and biomechanical properties in ovariectomized ratsHANLong,WUShuipei(79)

Improving effect and mechanism of Chinese arborvitae glycosides on the behavior of rat model of Alzheimer’s diseaseSUOJinhong,MOUHaijun,LIUXiaojuan,etal.(84)

Effectiveness of three different anesthetic techniques in intraventricular catheterization and its effect on survival rate of the ratsYANGYanan,SHUQing,CHENLi,etal.(89)

Comparison and evaluation of three different blood sampling methods in quailsLIGaoxi,LINZhijian,ZHANGBing(96)

Preparation and identification of rabbit anti-marmoset IgG-HRP conjugate antibodyCONGRixu,LIUXianju,TENGYongkang,etal.(101)

Establishment method of a rat model of renal ischemia-reperfusion injury by clamping the bilateral renal pedicles through backside and retroperitoneal incisionXIEMinhui,GUCuizhi,LIFengxia,etal.(106)

Advances in research on animal models of oral cancerXUGuoqiang,WEIJianing,SONGGuohua(111)

Research advances of application of tree shrew as an animal model of viral infectious diseasesZHOUFengmei,LIRunfeng,YUANBing,etal.(115)

Research on the strategy of eradication of HIV latent reservoirsTONGLing,XUEJing,WEIQiang(121)

A review on the treatment of spinal cord injury based on combining cell transplantation and biomaterial therapyTANGXihe,FANYimin,LANShengyong(127)

Issue 7

Experimental study on prevention of common iliac vein stenosis in miniature pigs by regional perfusion of paclitaxel to simulate drug-coated balloonsLUJingyuan,XUWenjian,SHIWanyin,etal.(1)

The process of CEMx174 cell infection by SIVmac239LIXiang,TONGLing,CONGZhe,etal.(7)

Establishment of diarrhea-predominant of irritable bowel syndrome (IBS-D) model rats by chronic restraint stress and a specialized dietMAXiaoling,XIATIGULIAbulizi,SHILeiling,etal.(12)

Ligustilide alleviates inflammatory reactions induced by ox-LDL in HUVECs through upregulation of miR-181bHUANGZhiyong,TIANGuangyong,CAOLing,etal.(18)

Effect of sevoflurane on proliferation of neural stem cells in neonatal ratsHUANGJianfeng,XIANHaiyan,HOUXiaoqiong(24)

Effect of focal cerebral ischemia/reperfusion injury onTMEM166 and neuron autophagyWANGYu,WANGTianlong,ZHAOLei,etal.(28)

Effect ofinuterointraperitoneal injection of human tumor HepG2 cells on the growth and development of fetal miceLIShanshan,SHUYun,CHENLai,etal.(33)

Establishment of a human acute leukemia pathological model in SCID beige mice using HL60 and HL60/ADR cell linesZHANGKun,XUHaomiao,CHENGJuan,etal.(43)

Effect of nutritional elements and protein on ovarian functions in female ratsWANGFeiqing,XIAShuhua,ZOUWenbing,etal.(52)

Effect of reed rhizome polysaccharides on hyperlipidemia in ratsCHENZhisheng,CHENJingyang,ZHANGPengyin,etal.(58)

Relationships between learning and memory abilities and levels of ACh, β-EP, SOD, and MDA in the cerebral cortex of mice with chronic aluminum toxicitiesMOSongyi,ZHANGLifeng,HUANGYanfeng,etal.(63)

Therapeutic effects ofAlismaorientaleextract on nonalcoholic fatty liver disease in rats and its mechanismGONGJie,DINGYan,GANZhongyuan,etal.(68)

Expression of HIF-1α and GLUT-1 in colorectal carcinoma tissues and its clinical significanceWUXueliang,WANGLikun,ZHOUHaifeng,etal.(77)

Invitroculture of dopamine neurons from newborn tree shrewLIJuan,ZENGXiaofeng,YANGGenmeng,etal.(82)

Establishment and evaluation of a long-term anesthesia protocol for studies of spinal cord injury in macaquesMAXiaocui,TANGTao,LIUShaojun(87)

Research progress of acid calponinLEILei,DAOQing,NIUChenghui,etal.(92)

Progress in the comparison of physiological structures and functions of mammalian bipolar cellsZHANGChi,HUMin,SUNXiaomei,etal.(97)

Research and commentary on the rat model of functional dyspepsia induced by compound factorsLONGTao,GUOBaojun,ZHAOYing,etal.(102)

Review of marmoset assisted reproductive technology and gene-modified modelsTENGYongkang,LIUYunbo(107)

Research progress on the mechanism ofSREBPsin regulation of articular cartilage degeneration in osteoarthritisYANGZhandong,YUHongyan,GAOJijun,etal.(113)

Pathological significance of the starry sky pattern in tumorsZHAOWenjie,QINChuan(118)

Research progress on chronic latent reactivation of primate cytomegalovirus-induced immune senescenceWANGYuhong,QUGuangjin,XIAOChong,etal.(124)

Issue 8

The establishment and implementation of an occupational health management system for laboratory animal facilitiesSHAOQiming，DOUMulin(1)

Importance of biosafety training in EHS management system for laboratory animal practitionersSONGZhigang，LIUFang，RENXiaonan，etal(7)

The application of disinfectants and the protection of occupational health in laboratory animal facilitiesLIChao，ZHANGHui，LIANGYangyang，etal(11)

Assessment of human respiratory protective equipment when using animal bedding filling or dumping machineWANGChangyao，QIANDanping，KONGQingxue，etal(16)

The design and analysis of exhaust treatment equipment for laboratory animal facilitiesLIUYi，YUEHuijuan，LIUJia，etal(21)

Effects of genipin on liver regeneration after partial hepatectomy in ob/ob miceBIYanghui，CUIXiaomeng，YUHaitian，etal(26)

Experimental research on PPy/PLA/BMSCs to treat spinal cord injuryRaynald，SHUBing，HUANGHua，etal(32)

Application of nucleic acid detection techniques for three mouse enteroviruses in mouse health monitoringLIXinyue，TONGWei，CONGRixu，etal(38)

Genetic diversity analysis of laboratory domestic ferret microsatellite DNALIUXianju，TENGYongkang，CONGRixu，etal(43)

Intradiscal injection of simvastatin-loaded PLGA microspheres retards progression of intervertebral disc degeneration in a rat modelCHENTao，XIJuqun，LIUZhongjun，etal(49)

Establishment of a rat model of acute and chronic fallopian tube inflammatory infertility caused byStaphylococcusaureusHUXijiao，LINChunsheng，LIShuoxi，etal(56)

Mammary tissue-specific modification of mouse BRCA1/BRCA2/CDH1 genes using CRISPR/Cas9CHENXi，XIANGXi，YANGManman，etal(62)

Experimental research on Shenfukang VI decoction and glomerulus electrostatic barrier in adriamycin nephropathy rats modelCAOHuan，LIUFang，BAIXiaohong，etal(70)

Protective effects of resuscitation-inducing herbs on acute incomplete cerebral ischemia in ratsHUANGLi，ZHUCaixia，ZHANGQinxin，etal(77)

Anti-influenza virus and antibacterial effects of Xiaoer Resuqing syrupWANGMin，CHENRongchang，JIYubin，etal(83)

Effects of rose and cream on fibronectin and basic fibroblast growth factor in rat models with stage III pressure ulcerJIYanqiong，GUOLihong，LIZixiang，etal(90)

miR-206 overexpression inhibits the invasion and migration of liver cancer cell line HepG2 by targeting VEGFAWANGXiaoming，YUShan，ZHAOXiaoji(95)

A rapid method for obtainingVav1 gene knockout stable cell linesGUOGuo，LISaichao，WANGLi，etal(101)

Revised fixation method for common carotid artery intubation in New Zealand rabbitsQIAOShaolin，QIXiaolin，WANGQianjin，etal(108)

Analysis and discussion of relative humidity fluctuation in ABSL-2 laboratoryGUXin，LVYang，LUXuancheng，etal(112)

Preclinical research progress of enlarging thrombolysis time window of ischemic stroke with tissue type plasminogen activator treatmentTAOYiran，LIUTingting，SUNFangling，etal(118)

Research progress on long noncoding RNA MIAT in human carcinomasSUNCheng，HUANGLining，LIJinglin，etal(124)

Progress in research on the NLRP3 inflammasome in hepatic diseaseKONGDelong，CUIJie(129)

Research advances for Pig-a gene mutation assayZHENGDandan，QINMeirong，WANGXiaowei，etal(135)

Issue 9

Comparison of imiquimod-induced psoriatic lesions in BALB/c and C57BL/6 miceWUJianping,XIEQian,CHENLin,etal.(01)

Diversity analysis of the tree shrew hindgut microbiota by Illumina PE250 sequencing technologyGUOYuqian,JIAOJianlin,YUANXin,etal.(07)

Dynamic changes of biochemical and physiological indexes in breeding a diabetic inbred Mongolian gerbil lineWANGYing,LIYing,WANGDongping,etal.(14)

Analysis of polymorphisms in the promoter region of thePPARγ2 gene in Wuzhishan minipigsPANJinchun,MINFangui,WANGXilong(21)

Effect of compound Ejiao slurry on the mouse endometriumDINGGuiqing,WEIHuafang,WANGLiqun,etal.(27)

DR5 and DcR2 protein expression in granulosa cells of ovaries of polycystic ovary syndrome ratsZHANGJuan,WANGLiqun,ZHOUYuexi,etal.(33)

Substance P in the digestive tract of a tree shrew cholesterol-induced gallstone modelLYULongbao,CHENLixiong,WANGJunbin,etal.(40)

Establishment of a hyperuricemia mouse model with renal damagePEIYixue,LIUYongjie,ZHANGDi,etal.(46)

Constructing an intrahepatic model of advanced liver cancer by injecting cancer cells through the hepatic portal veinCHAIYantao,JIANGQiyu,FENGFan,etal.(55)

Silencing Blimp-1 inhibits hepatoma cells by promoting IFN-γ expressionDENGHao,PENGQiwang,LIWei(61)

Effects of age on efficacy ofinvitrofertilization in non-obese diabetic miceYANTao,HUPing,XUChen,etal.(66)

Research on sharing service patterns of “Internet+” laboratory animal resourcesLIHuiping,WANGXiaoming,YANGJinchun,etal.(69)

Tissue morphological characteristics of liver from four commonly used laboratory animals compared with those of humanLIJing,WANGYanli,LIUEnqi(74)

Application of a quality control circle for reducing the rate of non-standardized behaviors in animal experimentsLIANGLei,YOUJinwei,HUWenjuan,etal.(78)

Evaluation of the operational effect of the animal nose-only inhalation exposure deviceHAOXinyan,XIANGZhiguang,GAOHong(83)

Development of a biosafety negative-pressure poultry isolatorZHANGZongxing,QIJiancheng,WUJinhui,etal.(90)

Research progress on cyclic noncoding RNA in oral squamous cell carcinomaWEIJianing,XUGuoqiang,GAOJiping,etal.(96)

A review of experimental studies on the behavior of rat models with abnormal emotion in Traditional Chinese MedicineZHANGPengheng,RUANLuwei,ZHUOZewei,etal.(100)

Application of tree shrews in human metabolic diseases and prospectsXIAWei,LAIYongjing,DULong,etal.(104)

Research progress on conversion of fibroblasts into motor neuronsSHIYuting,LIFeng(110)

A review of rat stellate ganglion blockHUKe,ZHANGBingdong(115)

Comparative medical analysis of the effect of rational use of antibacterial drugs on clinical surgical infection rateHUANGXiaoyan,ZHAOXirong,CAORuili(120)

Issue 10

Analysis of differential gene expression and function of APP/PS1 in prefrontal cortex of AD mice by RNA-seqSHIChanghua，ZHANGLing，CHENWei,etal.(1)

Expression pattern of zebrafishmcm5 and its role in somitogenesisZHANGYu，WUYongmei，LIUMin,etal.(8)

Dynamic comparison of blood and urine biochemistry in two models of renal calculiHAOZhiqiang,WANGQinzhang,NIZhao,etal.(15)

Establishment of an immune model of infection in aged miceYUANSonghua,FUWeihui,HEYongquan,etal.(20)

Comparison of heart rate variability and HPA axis activation effect in rats with bundling or isoflurane anesthesiaWANGXiaoyu,HEWei,MAFuqiang,etal.(28)

Comparison of blood physiological and biochemical indexes between normal Bama minipigs and an F5 generation with hyperglycemiaDENGJuncheng,SUXiaohua,LYUMing,etal.(36)

Influence of Qingre Huatan Jiedu prescription on Akt/JNK3/Caspase-3 and NF-κB signaling pathway in apoplexy-associated pneumonia ratsWANGTao,LIUHongxiang,WANGYing,etal.(42)

Effects of Icariin on signaling pathway of androgen receptor in orthotopic transplanted tumor of SCID mice with prostate cancerCHENDesen,HUXiyao,CHENShaoxiu,etal.(49)

MicroRNA-494 inhibits osteoblast differentiation and matrix mineralization through the TLR-4 pathwayKUANGJiabing,XUHao,ZHANGKeliang,etal.(55)

Comparison of two strains of rats used in transcutaneous electrical resistance testLUOFeiya,FENGKeran,ZHANGLuyong,etal.(61)

The effect and molecular mechanism ofDendrobiumcandidumpolysaccharides on chronic atrophic gastritis in ratsOUYANGYiming，LINGPing，LILinhai,etal.(67)

Expression and significance ofDlx2 gene in skull defect model of young sheepBIYujie，ZHOUHao，CUIYang,etal.(73)

Differential expression and signal transduction analysis of microRNA related to aging of human epidermal cellsHANYinshu(79)

The practice and exploration of non addictive analgesic teaching experiment in pharmacologyLIUFen,GUANFengying,ZHANGDawei,etal.(85)

Investigation of various bacteria in laboratory rats and mice by PCR assayFENGJie,XIEJianyun,WEIXiaofeng,etal.(89)

Improving education on the welfare of experimental animals among medical graduate studentsJUJiyu,XUYumei,GENGYunfeng,etal.(94)

Analysis of a new style of dry cage for rabbit rearingZOUYanbai,LIANGChunnan,ZHAOMinghai,etal.(98)

Progress of research on FKBP1B gene in cardiovascular and cerebrovascular systemsGAOYi,LYUYang,LIULixiang,etal.(106)

Application of multiplex PCR to detecting experimental animal pathogensZHANGFeiyan,ZHAOLing,JINJie,etal.(111)

Role of tryptophan-2,3-dioxygenase in central nervous system diseases and potential for associated therapeutic strategiesFUXiaofeng,HONGLuwei,WANGYuting,etal.(117)

Application and progress of the 3Rs’ principle for laboratory animals in sports science researchZUOQun,YUXinkai(122)

Ethical analysis of euthanasia methods for experimental animalsLINan,WANGTianqi,HEJialing,etal.(128)

Standardization of ethical review for laboratory animal welfare and interpretation of the new national standards in ChinaSUNDeming,LIWeiou,WANGTianqi,etal.(133)

Issue 11

Protective effect of 1,25(OH)2VD3on liver mitochondrial injury in ZDF ratsLIYanyan,FENGLiru,ZHANGHongmin,etal.(01)

Effect of emodin on adipose browning in ApoE knockout miceCHENGLong,DONGShifen,YUANYueying,etal.(08)

Expression of miR-34c in oral squamous cell carcinoma and its influence on biological behaviors of Tca8113 cellsCHANGKai,GAOJiping,SONGXiaona,etal.(15)

4T1 inflammatory breast cancer cell inoculation combined with corticosterone injection to establish a mouse model of breast cancer complicated with depressionYANGHui,MENGPan,YANGQin,etal.(21)

Pathological characteristics of liver injury in spontaneous type 2 diabetic db/db miceKANGJiali,LIANGWeishi,MENGXubing,etal.(27)

Comparison of collagen-induced and antigen-induced C57BL/6 mouse models of rheumatoid arthritisFANKaijian,WUJing,WANGTingyu(31)

Screening of single nucleotide polymorphism markers and their application to identification of four common strains of ratsZENGYulin,MENGYuhuan,ZHANGYu,etal.(36)

Ameliorating effect of Xingnaozaizao capsule on formaldehyde-induced memory impairment in miceSHENGZhihao,CHENYing,MARui,etal.(42)

Effect of curcumin pretreatment on renal pathological changes and the level of oxidative stress in rats with various degrees of heat stroke in a dry heat environmentLIJianying,ZHAOYinhui,KANGYan,etal.(48)

Establishment of a mouse model of pulmonary adenoma and its routine examination of blood and urine, blood biochemistry and pathologyZHANGXiuyan,GAOYaqi,CHENWeisheng,etal.(53)

Comparative analysis of egg quality and nutritional components between domesticated Tibetan chicken in Guangzhou and Wuhei chickenYUANJin,WUQinghong,CHENBangzhu,etal.(60)

Effect of GnRH-a combined with estrogen on endometriosis in a rat model and its recurrenceZHANGLingyu,LIUYinglei,QIAOHaifeng,etal.(67)

Scheduled imaging and pathological analysis of an orthotopic hepatic carcinoma model in nude miceSHENZhiyong,CHENYufeng,SHAOJingjing,etal.(74)

Analysis of microsatellite genetic structures of three outbred strains of guinea pigLIUDiwen,TANHaiming,CHENYanhong,etal.(81)

Establishment of luciferase and green fluorescent protein-labeled esophageal cancer cells for application in a mouse model andinvivoimagingBAIWen,PENGXiaoqing,WANGPeiwen,etal.(89)

Effect of geniposide on expression of IL-6, TNF-α, and IL-1β in an animal model of mastitisHUANGYongzhou,LIYi,CONGZhujun(95)

Establishment of a Sprague-Dawley rat model of limb ischemia-reperfusion injurySHENZhen,ZHUFuping,PANChengxi,etal.(100)

Detection of cardiac functions in rats using a new ultrasonic diagnostic apparatusCHENTingting,LIAOXianshan,ZENGLan,etal.(106)

Exploration of a teaching model of laboratory animal science for postgraduates under the “Double First Class”WUYanling,ZHANGXian,CUIZhenyu,etal.(111)

Reflections on the practical teaching of animal welfare and ethics to medical studentsGAOJianfeng,TANGHongbin,YANGSijun,etal.(115)

The practice of experimental animal research projects for comprehensive quality cultivation of college students under the concept of outcome-based educationJUJiyu,XUYumei,LIULinlin,etal.(119)

Exploration of offering an elective course of laboratory animal science for undergraduate students in traditional Chinese medical universities and collegesLIUJianwei,ZHANGMingxing,PANJianming,etal.(123)

Issue 12

Effect of a cytokine storm on immune responses against viral infection in aged miceYUANSonghua,HEYongquan,XUJianqing,etal.(1)

Comparison of the effect of glucosamine hydrochloride and its derivatives on the skeletal repair in zebrafishZHANGWenjuan,XUJingjin,YAOLiyun,etal.(9)

Effects of curcumin pretreatment on the oxidative stress and apoptosis of cardiomyocytes in heatstroke rats in a dry heat environmentMANa,LIJiaji,SONGLaiyang,etal.(14)

Immunohistochemical identification and fertility assessment of a mouse model of thin endometriumZHANGRuyue,LIRuijiao,ZHANGYinhong,etal.(19)

To establish a three dimensional visualization model of miniature pig renal vasculature and its significanceDENGJianquan,HuangHailong(27)

Effect of luteolin on the invasion and migration of papillary thyroid carcinoma TPC-1 cells and its mechanismZHONGYe，WANGChao，XUBo,etal.(32)

Experimental study on grouth and reproduction ofTlr4 knockout miceZHENGYang，WANGJiahui，LIULulu,etal.(38)

Effects of fluoxetine on behavior and hippocampal neurogenesis in rat model of post-stroke depressionLIAiping,TIANJing,ZHOUZhiwen,etal.(41)

Anti-tumor effect and immunological mechanism oflactobacilluscaseiin a rat model of gastric cancerZHANGDan,WANGYunye(48)

Selection of microsatellite loci for genetic analysis of experimental cat populationsJIASonghua,WANGHong,WEIJie,etal.(55)

Effect and mechanism of low molecular weight heparin calcium on mouse embryo implantationYANGWen,YANGYan,WUXiaoyan,etal.(61)

Establishment of mouse orthotopic transplantation tumor models of human hepatoma and comparison of their characteristicsYINJun，LIJINGDingsha，ZUOConglin,etal.(68)

Comparison of CYP enzyme activities in rat models of nonalcoholic fatty liver established by different methodsJINYi,XINGWei,LYUAizhen,etal.(75)

Evaluation of the left ventricular structure and function in cynomolgus monkeys with acute myocardial infarction based on echocardiographyWANGChengzhou,YANGQian,ZHANGCaiqiao(84)

Establishment and discussion of a physical evaluation system in the rhesus macaqueZHANGYulin,HUZhengfei,LIUChao,etal.(89)

Comparison of two staining methods for rat vaginal smearsZHANGTing,WANGYing,WANGLi(98)

Application of an automated control system to specific pathogen-free barrier facilities for laboratory animalsLIKexin,ZHANGFengmei,YANGGenling,etal.(102)

Research progress in experimental animal models of nasopharyngeal carcinomaXIAOYangyang,QINGJilin,LIBaoxuan,etal.(108)

Zebrafish: A new tool for novel nephrology drug discoveryWANGLing，CHENZhaohong(113)

Research progress of animal models of hereditary tyrosinemia type 1GUPeng,LIUWen,YUANJin,etal.(119)

Research review of the development of animal models of chemotherapy-induced diarrheaWUMengyu,DENGBo,JIALiqun(124)

Comparison of experimental maze tests used to assess the learning and memory abilities in rats and miceYANGYujie,LIYujiao,LIShanshan,etal.(129)