李水珠 莫基斌
[摘要] 目的 通過比較運(yùn)動(dòng)平板試驗(yàn)與冠脈造影結(jié)果,分析其臨床應(yīng)用價(jià)值。 方法 方便收集2018年4—12月入住該院心內(nèi)科75例疑似冠心病患者,所有患者均行運(yùn)動(dòng)平板試驗(yàn)與冠狀動(dòng)脈造影檢查。結(jié)果 運(yùn)動(dòng)平板試驗(yàn)中陽(yáng)性率72.0%,而冠狀動(dòng)脈造影術(shù)為53.3%,兩者比較差異有統(tǒng)計(jì)學(xué)意義(χ2=4.688,P<0.05)。運(yùn)動(dòng)平板試驗(yàn)的靈敏度為82.5%。將結(jié)果按性別分別分析,男性患者和女性患者運(yùn)動(dòng)平板試驗(yàn)陽(yáng)性率分別為72.7%、70.0%,而冠狀動(dòng)脈造影術(shù)分別為56.4%、45.0%,其中女性患者比較差異有統(tǒng)計(jì)學(xué)意義(χ2=7.013,P<0.05)。按受累血管數(shù)目分組為0支,單支,多支,運(yùn)動(dòng)平板試驗(yàn)陽(yáng)性率分別為50.0%,75.0%,83.9%,3組間比較差異有統(tǒng)計(jì)學(xué)意義(χ2=7.076,P<0.05)。結(jié)論 運(yùn)動(dòng)平板試驗(yàn)對(duì)診斷冠心病的敏感性較好,且受累血管數(shù)目越多陽(yáng)性率越高,可作為初篩冠心病的方法,但有假陽(yáng)性現(xiàn)象,以女性患者影響更明顯。因此在冠心病篩查時(shí)應(yīng)多方面綜合分析以提高診斷準(zhǔn)確性。
[關(guān)鍵詞] 運(yùn)動(dòng)平板試驗(yàn);冠狀動(dòng)脈造影;假陽(yáng)性;臨床應(yīng)用價(jià)值
[中圖分類號(hào)] R541? ? ? ? ? [文獻(xiàn)標(biāo)識(shí)碼] A? ? ? ? ? [文章編號(hào)] 1674-0742(2019)08(b)-0032-03
[Abstract] Objective To compare the clinical application value of exercise plate test and coronary angiography. Methods Convenient a total of 75 patients with suspected coronary heart disease who were admitted to our Department of Cardiology from April 2018 to December 2018 were enrolled. All patients underwent exercise plate and coronary angiography. Results The positive rate was 72.0% in the exercise plate test and 53.3% in the coronary angiography. The difference was statistically significant (χ2=4.688, P<0.05). The sensitivity of the exercise plate test was 82.5%. The results were analyzed by gender. The positive rate of exercise plate test in male patients and female patients was 72.7% and 70.0%, respectively, while coronary angiography was 56.4% and 45.0%, respectively. Among them, the difference was statistically significant (χ2=7.013, P<0.05). According to the number of affected vessels, the scores were 0, single, and multiple. The positive rate of exercise plate test was 50.0%, 75.0%, and 83.9%, respectively. The difference between the three groups was statistically significant (χ2=7.076, P<0.05). Conclusion The exercise plate test is more sensitive to the diagnosis of coronary heart disease, and the higher the number of affected blood vessels, the higher the positive rate. It can be used as a method for screening coronary heart disease, but there is a false positive phenomenon, which is more obvious in female patients. Therefore, in the screening of coronary heart disease should be comprehensive analysis in many aspects to improve the diagnostic accuracy.
[Key words] Exercise plate test; Coronary angiography; False positive; Clinical application value
隨著物質(zhì)生活改善及社會(huì)壓力對(duì)人體影響,近年冠狀動(dòng)脈粥樣硬化性心臟?。ü谛牟。┑陌l(fā)生率有所提高,且偏年輕化。目前雖然冠狀動(dòng)脈造影檢查仍然是確診冠心病的“金標(biāo)準(zhǔn)”,但運(yùn)動(dòng)平板試驗(yàn)較之相對(duì)安全、無(wú)創(chuàng)、簡(jiǎn)單、廉價(jià)且無(wú)需住院,更容易為患者接受,故常作為疑似冠心病患者的初步篩查手段。為此,該研就對(duì)2018年4—12月入住該院心內(nèi)科75例疑似冠心病患者進(jìn)行了運(yùn)動(dòng)平板試驗(yàn),并對(duì)其展開分析討論?,F(xiàn)報(bào)道如下。
運(yùn)動(dòng)平板試驗(yàn)操作簡(jiǎn)單易于普及,且診斷冠心病的敏感性較好,可以作為冠心病初篩的常規(guī)檢查方法。然而與冠脈造影檢查對(duì)比,存在假陽(yáng)性,因此臨床中因結(jié)合患者性別、年齡、臨床癥狀、既往病史等進(jìn)行綜合分析,必要時(shí)配合其他檢查手段,如碘劑注射后對(duì)冠狀動(dòng)脈進(jìn)行CT檢查(CTA),甚至直接進(jìn)行冠狀動(dòng)脈造影以明確。
[參考文獻(xiàn)]
[1]? 王慧,陳瑤,郭勇娟,等.浙江省心電圖平板運(yùn)動(dòng)試驗(yàn)操作與診斷規(guī)范(試用版)[C]//浙江省醫(yī)學(xué)心電與起搏學(xué)術(shù)分會(huì).2016年浙江省醫(yī)學(xué)會(huì)心電生理與起搏學(xué)術(shù)年會(huì)論文匯編.中國(guó)浙江湖州:2016.
[2]? 巢為農(nóng),吳晶晶,王炳銀,等.運(yùn)動(dòng)平板試驗(yàn)假陽(yáng)性相關(guān)因素的分析[J].臨床心電學(xué)雜志.2015,24(1):27-30.
[3]? 張虹.運(yùn)動(dòng)平板試驗(yàn)假陽(yáng)性結(jié)果與冠狀動(dòng)脈造影結(jié)果對(duì)比分析[J].河北醫(yī)藥.2013,35(11):1639-1641.
[4]? 張曉紅,和平,王科程,等.運(yùn)動(dòng)平板試驗(yàn)診斷冠心病診斷價(jià)值研究[J].臨床軍醫(yī)雜志.2018,46(5):588-589.
[5]? 張俊芳,張利峰,王獻(xiàn)忠.運(yùn)動(dòng)平板試驗(yàn)診斷無(wú)癥狀糖尿病冠心病的臨床意義[J].中西醫(yī)結(jié)合心腦血管病雜志,2013, 11(1):108-109.
[6]? Peteiro J,Bouzas-Mosquera A,Broulion FJ,et al.Prognostic value of peak and post-exercise treadmill exercise echocardiography in patients with known or suspected coronary artery disease,Eur Heart J,2010,31(2):187-195.
[7]? 梁子光.84例疑似冠心病患者心電圖平板試驗(yàn)的臨床應(yīng)用分析[J].臨床醫(yī)藥實(shí)踐.2016,5(1):75-77.
[8]? 黃素華, 黃繼煥, 林小秀. 運(yùn)動(dòng)平板試驗(yàn)與動(dòng)態(tài)心電圖在中老年冠心病診斷中的應(yīng)用價(jià)值分析[J]. 基層醫(yī)學(xué)論壇, 2017, 21(13):1678-1679.
[9]? Yang H , Huang Z , Lou Y , et al. Limited value of recovery phase-limitedST segment depression of treadmill exercise test[J]. Chinese Medical Journal,2014, 127(4):742-746.
[10]? 丁盛梅. 12導(dǎo)聯(lián)動(dòng)態(tài)心電圖聯(lián)合平板運(yùn)動(dòng)試驗(yàn)對(duì)冠狀動(dòng)脈粥樣硬化性心臟病患者診斷敏感性及特異性的影響[J].中國(guó)藥物經(jīng)濟(jì)學(xué), 2017,12(9):130-132.
[11]? Carreira M A M Q , Nogueira André B, Pena F M , et al. Detection of Autonomic Dysfunction in Hemodialysis Patients Using the Exercise Treadmill Test: The Role of the Chronotropic Index, Heart Rate Recovery, and R-R Variability[J]. PLOS ONE,2015,10(6):123-128.
[12]? 胡玉萍,屈莉,心電圖平板運(yùn)動(dòng)試驗(yàn)對(duì)比動(dòng)態(tài)心電圖在冠心病的診斷中的應(yīng)用價(jià)值[J].臨床醫(yī)學(xué)研究與實(shí)踐, 2017,2(23):138-139.
(收稿日期:2019-05-19)